anti-Human Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) Antikörper für Flow Cytometry

Recommended Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) (COCH) Antikörper
  • AW122937
  • Coch-5B2
  • D12H14S564E
  • COCH-5B2
  • COCH5B2
  • DFNA9
  • cochlin
  • coagulation factor C homolog (Limulus polyphemus)
  • coagulation factor C homolog, cochlin (Limulus polyphemus)
  • Coch
  • COCH
Epitop
AA 398-428, Middle Region
17
10
9
9
8
8
7
4
3
1
1
Reaktivität
Human
58
11
8
4
4
4
4
3
2
2
1
1
Wirt
Kaninchen
55
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
4
4
4
4
4
Applikation
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
52
32
17
16
3
2
1
1
Hersteller
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Bilder

Produktnummer ABIN951612
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN656833 FACS IHC (p) WB Rabbit Ig AA 399-428, Center Anmelden zum Anzeigen Polyclonal
1 ABIN5536740 FACS IHC (p) WB Rabbit Ig Fraction AA 399-428 Anmelden zum Anzeigen Polyclonal
1 ABIN2595750 ELISA FACS IHC WB Rabbit IgG AA 398-428 Anmelden zum Anzeigen Polyclonal
1 ABIN2235881 FACS IHC ELISA WB FITC Rabbit IgG AA 398-428, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN2235875 FACS IHC ELISA WB PE Rabbit IgG AA 398-428, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN2235879 FACS IHC ELISA WB APC Rabbit IgG AA 398-428, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN2235886 FACS IHC ELISA WB Rabbit IgG AA 398-428, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN1975541 FACS IHC ELISA WB PE Rabbit IgG AA 399-428 Anmelden zum Anzeigen Polyclonal
1 ABIN1964529 FACS IHC ELISA WB APC Rabbit IgG AA 399-428 Anmelden zum Anzeigen Polyclonal
1 ABIN1962150 FACS IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 399-428 Anmelden zum Anzeigen Polyclonal
1 ABIN1970963 FACS IHC ELISA WB FITC Rabbit IgG AA 399-428 Anmelden zum Anzeigen Polyclonal
1 ABIN1968664 FACS IHC ELISA WB Biotin Rabbit IgG AA 399-428 Anmelden zum Anzeigen Polyclonal
1 ABIN1972815 FACS IHC ELISA WB HRP Rabbit IgG AA 399-428 Anmelden zum Anzeigen Polyclonal
1 ABIN2235880 FACS IHC ELISA WB Biotin Rabbit IgG AA 398-428, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN2235878 FACS IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 398-428, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN1813225 FACS IHC (p) WB Rabbit AA 399-428 Anmelden zum Anzeigen Polyclonal

General

Antigen Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) (COCH) Antikörper
Epitop AA 398-428, Middle Region
(17), (10), (9), (9), (8), (8), (7), (4), (3), (1), (1)
Reaktivität Human
(58), (11), (8), (4), (4), (4), (4), (3), (2), (2), (1), (1)
Wirt Kaninchen
(55), (3)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(4), (4), (4), (4), (4), (4)
Applikation Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(52), (32), (17), (16), (3), (2), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Spezifität This antibody reacts to COCH.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 398-428 amino acids from the Central region of human COCH
Isotyp Ig

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung Cochlin (COCH Antibody Abstract)
Hintergrund The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94 % and 79 % amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq].Synonyms: COCH, COCH-5B2, COCH5B2
Molekulargewicht 59483 Da
Gen-ID 1690
NCBI Accession NP_001128530
Pathways Sensory Perception of Sound

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Ikezono, Sugizaki, Shindo, Sekiguchi, Pawankar, Baba, Yagi: "CTP (Cochlin-tomoprotein) detection in the profuse fluid leakage (gusher) from cochleostomy." in: Acta oto-laryngologica, Vol. 130, Issue 8, pp. 881-7, 2010

Yao, Py, Zhu, Bao, Yuan: "Role of protein misfolding in DFNA9 hearing loss." in: The Journal of biological chemistry, Vol. 285, Issue 20, pp. 14909-19, 2010

Baek, Cho, Choi, Kim, Zhao, Sagong, Kim, Jeong: "The Trp117Arg mutation of the COCH gene causes deafness in Koreans." in: Clinical genetics, Vol. 77, Issue 4, pp. 399-403, 2010

Lee, Gabelt, Faralli, Peters, Brandt, Kaufman, Bhattacharya: "COCH transgene expression in cultured human trabecular meshwork cells and its effect on outflow facility in monkey organ cultured anterior segments." in: Investigative ophthalmology & visual science, Vol. 51, Issue 4, pp. 2060-6, 2010

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010

Bilder

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Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) (COCH) (AA 398-428), (Middle Region) antibody (ABIN951612) COCH Antibody (Center) flow cytometric analysis of Hela cells (right histogram)...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) (COCH) (AA 398-428), (Middle Region) antibody (ABIN951612) COCH Antibody (Center) immunohistochemistry analysis in formalin fixed and para...
Western Blotting (WB) image for anti-Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) (COCH) (AA 398-428), (Middle Region) antibody (ABIN951612) Western blot analysis of COCH (arrow) using rabbit polyclonal COCH Antibody (Ce...