anti-Meerschweinchen Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) Antikörper für Western Blotting

Recommended Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) Antikörper
  • EFNL3
  • nAChRB2
  • NACHRB2
  • Acrb-2
  • Acrb2
  • C030030P04Rik
  • [b]2-nAchR
  • cholinergic receptor nicotinic beta 2 subunit
  • cholinergic receptor nicotinic beta 2 subunit S homeolog
  • cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
  • CHRNB2
  • chrnb2.S
  • Chrnb2
Epitop
Middle Region
6
4
3
3
3
2
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Schwein, Ratte (Rattus), Yeast
55
16
13
10
6
6
4
3
3
3
3
3
2
Wirt
Kaninchen
33
19
4
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
Applikation
Western Blotting (WB)
54
31
9
8
3
3
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2780201
$ 229.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2125654 ABIN2776104 IHC WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
1 ABIN202670 WB Rabbit IgG AA 21-70 Anmelden zum Anzeigen Polyclonal
1 ABIN214742 IHC (p) WB Rabbit AA 21-70 Anmelden zum Anzeigen Polyclonal

General

Antigen Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) Antikörper
Epitop Middle Region
(6), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Schwein, Ratte (Rattus), Yeast
(55), (16), (13), (10), (6), (6), (4), (3), (3), (3), (3), (3), (2)
Wirt Kaninchen
(33), (19), (4)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(54), (31), (9), (8), (3), (3), (2), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Sequenz KIEVKHFPFD QQNCTMKFRS WTYDRTEIDL VLKSEVASLD DFTPSGEWDI
Homologie Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%, Yeast: 77%
Produktmerkmale This is a rabbit polyclonal antibody against CHRNB2. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Protein A purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CHRNB2

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung CHRNB2 (CHRNB2 Antibody Abstract)
Hintergrund Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy . Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3), outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M, which occurred de novo in twins, markedly increases the receptor's sensitivity to acetylcholine. Phenotypically, the mutation is associated not only with typical ADNFLE, but also with distinct deficits in memory. The cognitive problems are most obvious in tasks requiring the organization and storage of verbal information.
Alias Symbols: EFNL3, nAChRB2
Protein Interaction Partner: CRELD2, CHRNA4, CHRNA2,
Protein Size: 502
Molekulargewicht 57 kDa
Gen-ID 1141
NCBI Accession NM_000748, NP_000739
UniProt P17787
Pathways Sensory Perception of Sound, Feeding Behaviour

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 502 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Feng, Niu, Xing, Xu, Chen, Peng, Wang, Laird, Xu: "A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men." in: American journal of human genetics, Vol. 75, Issue 1, pp. 112-21, 2004

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (Middle Region) antibody (ABIN2780201) WB Suggested Anti-CHRNB2 Antibody Titration: 5.0ug/ml
ELISA Titer: 1...