anti-Human Caspase 3 Antikörper für Flow Cytometry

Recommended Caspase 3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Antikörper
  • CC3
  • CG14902
  • Cas3
  • Casp 3
  • Casp3
  • Caspase-3
  • DECAY
  • Decay
  • Dmel\\CG14902
  • Drosophila executioner caspase related to Apopain/Yama
  • caspase 3
  • caspase-3
  • CG7788
  • DRICE
  • Dmel\\CG7788
  • DrICE
  • DrIce
  • Drice
  • ICE
  • crice
  • drICE
  • drIce
  • drice
  • ice
  • A830040C14Rik
  • AC-3
  • Apopain
  • CPP32
  • Lice
  • Yama
  • mldy
  • CPP32B
  • SCA-1
  • xcpp32
  • caspase 3, apoptosis-related cysteine peptidase
  • death executioner caspase related to Apopain/Yama
  • CG7788 gene product from transcript CG7788-RA
  • caspase 3
  • CASP3
  • decay
  • Ice
  • Casp3
  • casp3
Epitop
AA 219-248, C-Term
43
33
27
24
22
21
19
19
16
15
12
12
12
11
10
10
9
7
6
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
574
307
254
47
46
37
29
27
24
20
18
17
17
12
9
8
7
4
2
2
Wirt
Kaninchen
465
162
19
4
2
Klonalität
Polyklonal
Konjugat
Dieser Caspase 3 Antikörper ist unkonjugiert
27
24
19
14
9
9
9
6
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
489
241
219
144
94
76
55
52
45
29
28
13
9
9
7
5
4
3
2
2
2
2
2
2
2
1
1
1
1
Optionen
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Bilder

Produktnummer ABIN655271
335,24 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
14.326701 ABIN391813 FACS IHC (p) WB Rabbit Ig AA 60-90, Center Anmelden zum Anzeigen Polyclonal 3
14.326701 ABIN4897861 FACS Alexa Fluor 488 Rabbit IgG Anmelden zum Anzeigen 269518
14.326701 ABIN3030305 FACS IHC ELISA WB Rabbit Ig Fraction AA 219-248 Anmelden zum Anzeigen Polyclonal
14.326701 ABIN3030306 FACS IHC ELISA WB Rabbit Ig Fraction AA 60-90 Anmelden zum Anzeigen Polyclonal
14.326701 ABIN3030296 FACS IHC ELISA WB Rabbit Ig Fraction AA 149-179 Anmelden zum Anzeigen Polyclonal
14.326701 ABIN5542610 ELISA FACS ICC IHC WB Mouse IgG1 AA 29-175 Anmelden zum Anzeigen 3D4D7
1 ABIN252651 CyTOF EM FACS ICC IF IHC IHC (fro) IHC (p) SimWes WB Mouse IgG1 kappa Anmelden zum Anzeigen 31A1067 107
1 ABIN651176 FACS IHC (p) WB Rabbit Ig AA 149-179, Asp175 Anmelden zum Anzeigen Polyclonal 1
1 ABIN5556200 EIA FACS IHC (p) WB Rabbit Ig Fraction AA 226-256, C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN4288095 FACS IHC IHC (p) IP WB Rabbit Anmelden zum Anzeigen Polyclonal 15
1 ABIN4288106 FACS ICC IF IHC (fro) IHC (p) WB DyLight 488 Mouse IgG1 kappa Anmelden zum Anzeigen 31A1067 1
1 ABIN2665464 FACS Rabbit Anmelden zum Anzeigen Polyclonal 4
1 ABIN5027753 FACS IHC WB Mouse IgG1 Anmelden zum Anzeigen ABM11D3
1 ABIN4880596 ELISA FACS WB Mouse IgG1 AA 29-175 Anmelden zum Anzeigen 3D4D7
1 ABIN4288121 CyTOF ELISA FACS ICC IHC WB Mouse Anmelden zum Anzeigen 3D4D10
1 ABIN4288122 CyTOF ELISA FACS ICC IHC WB Mouse Anmelden zum Anzeigen 3D4D7
1 ABIN470500 ICC FACS IF ELISA Alexa Fluor 488 Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2219054 IC FACS IF ELISA Alexa Fluor 488 Rabbit IgG cleaved Anmelden zum Anzeigen Polyclonal
1 ABIN219229 FACS IHC (fro) IF IHC (p) IP WB Rabbit IgG N-Term Anmelden zum Anzeigen
1 ABIN2690044 FACS PE Rabbit IgG AA 60-100 Anmelden zum Anzeigen Polyclonal

General

Antigen Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Antikörper
Epitop AA 219-248, C-Term
(43), (33), (27), (24), (22), (21), (19), (19), (16), (15), (12), (12), (12), (11), (10), (10), (9), (7), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(574), (307), (254), (47), (46), (37), (29), (27), (24), (20), (18), (17), (17), (12), (9), (8), (7), (4), (2), (2)
Wirt Kaninchen
(465), (162), (19), (4), (2)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Dieser Caspase 3 Antikörper ist unkonjugiert
(27), (24), (19), (14), (9), (9), (9), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(489), (241), (219), (144), (94), (76), (55), (52), (45), (29), (28), (13), (9), (9), (7), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 Publikationen vorhanden
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Produktdetails anti-Caspase 3 Antikörper

Target Details Caspase 3 Anwendungsinformationen Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN655271) Bilder
Spezifität This CASP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-256 amino acids from the C-terminal region of human CASP3.
Homologie Mouse (Murine),Monkey,Rat (Rattus),Rabbit
Reinigung This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This CASP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-248 AA from the C-terminal region of human CASP3.
Klon RB14883
Isotyp Ig

Target Details Caspase 3

Produktdetails anti-Caspase 3 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN655271) Bilder zurück nach oben
Antigen
Andere Bezeichnung CASP3 (CASP3 Antibody Abstract)
Hintergrund This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq].
Synonyms: Caspase-3,CASP3,CPP32
Molekulargewicht 31608 DA
Gen-ID 836
NCBI Accession NP_004337, NP_116786
UniProt P42574
Forschungsgebiet Apoptosis/Necrosis, Signaling, Phospho-specific antibodies, Protein Modifications, Metabolism, Cell Structure
Pathways Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation

Anwendungsinformationen

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN655271) Bilder zurück nach oben
Applikationshinweise WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Anwendungsinformationen ProductDetails: References for anti-Caspase 3 antibody (ABIN655271) Bilder zurück nach oben
Format Liquid
Konzentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months

ProductDetails: References for anti-Caspase 3 antibody (ABIN655271)

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Würstle, Laussmann, Rehm: "The caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8, -3, -6 signaling." in: The Journal of biological chemistry, Vol. 285, Issue 43, pp. 33209-18, 2010

Srikanth, Wall, Maldonado-Contreras, Shi, Zhou, Demma, Mumy, McCormick: "Salmonella pathogenesis and processing of secreted effectors by caspase-3." in: Science (New York, N.Y.), Vol. 330, Issue 6002, pp. 390-3, 2010

Burke, Smith, Smith: "cIAP1 cooperatively inhibits procaspase-3 activation by the caspase-9 apoptosome." in: The Journal of biological chemistry, Vol. 285, Issue 39, pp. 30061-8, 2010

Bilder

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Anwendungsinformationen Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN655271) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) (AA 219-248), (C-Term) antibody (ABIN655271) CASP3 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/l...
Immunohistochemistry (IHC) image for anti-Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) (AA 219-248), (C-Term) antibody (ABIN655271) CASP3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin ...
Flow Cytometry (FACS) image for anti-Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) (AA 219-248), (C-Term) antibody (ABIN655271) CASP3 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram...