TYRO3 Proteine (TYRO3)

Bezeichnung:
TYRO3 Protein Tyrosine Kinase Proteine (TYRO3)
Auf www.antikoerper-online.de finden Sie aktuell 22 TYRO3 Protein Tyrosine Kinase (TYRO3) Proteine von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TYRO3 Antikörper (190) und TYRO3 Kits (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 233 TYRO3 Produkte verfügbar.
Synonyme:
AI323366, Brt, BYK, DKFZp469I0432, Dtk, Etk-2, ksy, LOC100231598, MGC145734, REK, Rse, Sky, Tif, TYRO3, xksy
alle Proteine anzeigen Gen GeneID UniProt
TYRO3 7301 Q06418
TYRO3 25232 P55146
TYRO3 22174 P55144

Weitere Synonyme anzeigen

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Am meisten referenzierte TYRO3 Proteine

  1. Human TYRO3 Protein expressed in HEK-293 Cells - ABIN2181883 : Shimojima, Takada, Ebihara, Neumann, Fujioka, Irimura, Jones, Feldmann, Kawaoka: Tyro3 family-mediated cell entry of Ebola and Marburg viruses. in Journal of virology 2006 (PubMed)
    Zeige alle 3 Referenzen für 2181883

Weitere Proteine zu TYRO3 Interaktionspartnern

Human TYRO3 Protein Tyrosine Kinase (TYRO3) Interaktionspartner

  1. Patients with macroalbuminuria diabetes had higher circulating levels of sMer and more urinary soluble Tyro3 and sMer than normoalbuminuric diabetics. Increased clearance of sTyro3 and sMer was associated with loss of tubular Tyro3 and Mer (zeige MERTK Proteine) expression in diabetic nephropathy tissue. During in vitro diabetes, human kidney cells had down-regulation of Tyro3 and Mer (zeige MERTK Proteine) mRNA and increased shedding of sTyro3 and sMer.

  2. TYRO3 is overexpressed in the early stage of colon cancer development and aberrant expression of TYRO3 promotes tumorigenesis and induces EMT (zeige ITK Proteine) through the regulation of SNAI1 (zeige SNAI1 Proteine).

  3. In this paper, we review the biology of the Gas6 (zeige GAS6 Proteine)/Tyro3, Axl (zeige AXL Proteine), and MerTK (zeige MERTK Proteine)(collectively named TAM (zeige CCNA1 Proteine) system)and the current evidence supporting its potential role in the pathogenesis of multiple sclerosis .

  4. these data suggest that Tyro3 contributes significantly to tumor growth, aggressiveness and liver dysfunction

  5. Tyro3 gene dosage modulates Mertk (zeige MERTK Proteine)-associated retinal degeneration, provide strong evidence for a direct role for TYRO3 in RPE (zeige RPE Proteine) phagocytosis, and suggest that an eQTL (zeige EQTN Proteine) can modify a recessive Inherited photoreceptor degenerations.

  6. The mRNA expression levels of Tyro-3, Axl (zeige AXL Proteine) were decreased in pSS (zeige CDSN Proteine) patients. When considering the plasma level, increased levels of soluble Mer (zeige MERTK Proteine) was observed with statistically significant difference.

  7. genetic ablation of a receptor tyrosine kinase (zeige RET Proteine) encoded byTyro3in mice or the functional neutralization of its ortholog in human dendritic cells resulted in enhanced type 2 immunity.

  8. the results of the present study demonstrated that the acquired taxol resistance of ovarian cancer cells was associated with ROS (zeige ROS1 Proteine)-dependent upregulation in the expression of Tyro3 RTK and the subsequent activation of Akt (zeige AKT1 Proteine).

  9. Tetherin (zeige BST2 Proteine) phosphorylation induces the recruitment of Syk (zeige SYK Proteine) which is required for downstream NF-kappaB (zeige NFKB1 Proteine) activation.

  10. These studies demonstrate that, despite their similarity, TYRO3, AXL, and MER are likely to perform distinct functions in both immunoregulation and the recognition and removal of ACs.

Mouse (Murine) TYRO3 Protein Tyrosine Kinase (TYRO3) Interaktionspartner

  1. This study mapped the autophosphorylation sites of murine Tyro3 to tyrosine 723 and 756, with K540 being required for its kinase activity.

  2. Axl (zeige AXL Proteine), Mertk (zeige MERTK Proteine) and Tyro3 receptors are not required for Zika virus entry and infection.

  3. Tyro3 gene dosage modulates Mertk (zeige MERTK Proteine)-associated retinal degeneration, provide strong evidence for a direct role for TYRO3 in RPE (zeige RPE Proteine) phagocytosis, and suggest that an eQTL (zeige EQTN Proteine) can modify a recessive Inherited photoreceptor degenerations.

  4. genetic ablation of a receptor tyrosine kinase (zeige ERBB3 Proteine) encoded byTyro3in mice or the functional neutralization of its ortholog in human dendritic cells resulted in enhanced type 2 immunity.

  5. These results suggest that TAM (zeige CCNA1 Proteine) receptors support NSCs survival, proliferation and differentiation by regulating expression of neurotrophins, especially the nerve growth factor.

  6. Optimal TAM (zeige CCNA1 Proteine) signaling requires coincident TAM (zeige CCNA1 Proteine) ligand engagement of both its receptor and the phospholipid phosphatidylserine regulating TAM (zeige CCNA1 Proteine) receptor tyrosine kinases Tyro3, Axl (zeige AXL Proteine), and Mer (zeige ERH Proteine) and their ligands Gas6 (zeige GAS6 Proteine) and Protein S.

  7. These findings indicate that Tyro3 is a critical signal for synovial hyperplasia, osteoclast differentiation and bone erosion during arthritis.

  8. Axl (zeige AXL Proteine) and Mer (zeige ERH Proteine) (TAM (zeige CCNA1 Proteine)) receptor tyrosine kinases (RTKs) developed persistent inflammatory liver damage resembling AIH. Tyro3(-/-)Axl (zeige AXL Proteine)(-/-)Mer (zeige ERH Proteine)(-/-) triple mutant (TAM (zeige CCNA1 Proteine)(-/-)) mice exhibited chronic hepatitis

  9. Adult brain neurogenesis is reduced in the hippocampus of the Tyro3-/-Axl (zeige AXL Proteine)-/-Mertk (zeige MERTK Proteine)-/- triple-knockout but not in single Tyro3-/- knockouts.

  10. Chronic systemic inflammation and autoimmune disorders in the Tyro3, Axl (zeige AXL Proteine) and Mertk (zeige MERTK Proteine) knockout mice cause neuronal damage and death.

TYRO3 Protein Überblick

Protein Überblick

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.

Alternative names and synonyms associated with TYRO3

  • TYRO3 protein tyrosine kinase (TYRO3)
  • TYRO3 protein tyrosine kinase (tyro3)
  • TYRO3 protein tyrosine kinase (LOC100231598)
  • TYRO3 protein tyrosine kinase (Tyro3)
  • TYRO3 protein tyrosine kinase 3 (Tyro3)
  • AI323366 Protein
  • Brt Protein
  • BYK Protein
  • DKFZp469I0432 Protein
  • Dtk Protein
  • Etk-2 Protein
  • ksy Protein
  • LOC100231598 Protein
  • MGC145734 Protein
  • REK Protein
  • Rse Protein
  • Sky Protein
  • Tif Protein
  • TYRO3 Protein
  • xksy Protein

Bezeichner auf Proteinebene für TYRO3

TYRO3 protein tyrosine kinase , Tyrosine-protein kinase receptor TYRO3 , tyrosine-protein kinase receptor TYRO3 , developmental receptor tyrosine kinase , tyrosine-protein kinase DTK , tyrosine-protein kinase receptor TYRO3-like , tyrosine-protein kinase RSE , tyrosine-protein kinase SKY , tyrosine-protein kinase TIF , tyrosine-protein kinase byk , Bruton agammaglobulinemia tyrosine kinase , TYRO3 protein tyrosine kinase 3 , Axl-related receptor tyrosine kinase , protein-tyrosine kinase , retina-expressed kinase , Xenopus kinase of Sky family , tyrosine kinase , TK19-2 , etk2/tyro3

GENE ID SPEZIES
487509 Canis lupus familiaris
710902 Macaca mulatta
780188 Xenopus (Silurana) tropicalis
788224 Bos taurus
100171516 Pongo abelii
100231598 Taeniopygia guttata
30709 Danio rerio
100403101 Callithrix jacchus
100471250 Ailuropoda melanoleuca
100515870 Sus scrofa
7301 Homo sapiens
25232 Rattus norvegicus
395336 Gallus gallus
398301 Xenopus laevis
22174 Mus musculus
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