anti-TUB (TUB) Antikörper

Bezeichnung:
anti-Tubby Homolog (Mouse) Antikörper (TUB)
Auf www.antikoerper-online.de finden Sie aktuell 10 Tubby Homolog (Mouse) (TUB) Antikörper von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TUB Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 15 TUB Produkte verfügbar.
Synonyme:
MGC78808, MGC79522, MGC80126, MGC84061, rd5, tub, tubby

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anti-Human TUB Antikörper:

anti-Mouse (Murine) TUB Antikörper:

anti-Rat (Rattus) TUB Antikörper:

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Am meisten referenzierte anti-TUB Antikörper

  1. Dog (Canine) Polyclonal TUB Primary Antibody für WB - ABIN2787451 : Snieder, Wang, Shiri-Sverdlov, van Vliet-Ostaptchouk, Hofker, Perks, Spector, ODell: TUB is a candidate gene for late-onset obesity in women. in Diabetologia 2007 (PubMed)

Weitere Antikörper gegen TUB Interaktionspartner

Human Tubby Homolog (Mouse) (TUB) Interaktionspartner

  1. Tubby and Tulp1 mediated phagocytosis through MerTK-dependent signaling with non-muscle myosin II redistribution leading to colocalization of phagocytosed vesicles with rearranged NMMIIA.

  2. Tubby and Tulp1 (zeige TULP1 Antikörper) are bridging molecules with their N-terminal region as MERTK (zeige MERTK Antikörper)-binding domain and C-terminal region as phagocytosis prey-binding domain.

  3. Tubby and Tulp1 (zeige TULP1 Antikörper) function as phagocytosis sigmals (eat-me) for retinal pigment epithelium cells and other phagocytes.

  4. TUB could be an important factor in controlling the central regulation of body weight in humans.

  5. TUB is a candidate gene for late-onset obesity in humans

  6. Genetic variation of the TUB gene was associated with both body composition and macronutrient intake, suggesting that TUB might influence eating behavior

  7. Mouse Tubby protein may function as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, providing a direct link between G-protein signaling and the regulation of gene expression.

Mouse (Murine) Tubby Homolog (Mouse) (TUB) Interaktionspartner

  1. We found that the mutant Tub proteins were mostly localized to puncta found in the perinuclear region and that the C-terminus was important for its solubility. our results suggest that the malfunctions of the Tub mutant are caused by its misfolding and subsequent localization to aggresomes.

  2. These results suggest that tubby is a ligand to facilitate microglial phagocytosis through MerTK (zeige MERTK Antikörper) for the maintenance of CNS homeostasis.

  3. Mtap1a (zeige MAP1A Antikörper), which modifies hearing loss in Tub(tub/tub) mice, also modifies retinal degeneration in Tub and Tulp1 (zeige TULP1 Antikörper) mice; functionally nonredundant members of the TULP family (TUB and TULP1 (zeige TULP1 Antikörper)) share a common functional interaction with MTAP1A (zeige MAP1A Antikörper)

  4. Tubby and Tulp1 (zeige TULP1 Antikörper) function as phagocytosis sigmals (eat-me) for retinal pigment epithelium cells and other phagocytes.

  5. TUB plays a role in insulin (zeige INS Antikörper) signalling and fuel homeostasis in adipocytes.

  6. Data show that agouti-related protein (zeige AGRP Antikörper) mRNA levels are significantly lower in obese tub/tub mice as compared to tub/+ mice.

  7. Tubby secretion is partially dependent on its PI(4,5)P(2)-binding activity with an essential secretory signal in the N-terminus.

TUB Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with TUB

  • tubby homolog (mouse) (TUB) Antikörper
  • tubby homolog (tub) Antikörper
  • tubby homolog (mouse) (tub) Antikörper
  • tubby protein homolog (LOC100563100) Antikörper
  • tubby protein homolog (LOC100566184) Antikörper
  • tubby bipartite transcription factor (TUB) Antikörper
  • tubby candidate gene (Tub) Antikörper
  • tubby homolog (mouse) (Tub) Antikörper
  • MGC78808 Antikörper
  • MGC79522 Antikörper
  • MGC80126 Antikörper
  • MGC84061 Antikörper
  • rd5 Antikörper
  • tub Antikörper
  • tubby Antikörper

Bezeichner auf Proteinebene für TUB

tubby homolog (mouse) , tubby (mouse homolog) , tubby homolog , tubby protein homolog , tubby homologue , retinal degeneration 5 , tubby protein

GENE ID SPEZIES
280949 Bos taurus
423061 Gallus gallus
444597 Xenopus laevis
466436 Pan troglodytes
485377 Canis lupus familiaris
493219 Xenopus (Silurana) tropicalis
539051 Bos taurus
706054 Macaca mulatta
100070898 Equus caballus
100342264 Oryctolagus cuniculus
446449 Xenopus laevis
100456166 Pongo abelii
100520318 Sus scrofa
100546143 Meleagris gallopavo
100563100 Anolis carolinensis
100566184 Anolis carolinensis
100582760 Nomascus leucogenys
7275 Homo sapiens
22141 Mus musculus
25609 Rattus norvegicus
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