Son of Sevenless Homolog 1 (Drosophila) ELISA Kits (SOS1)
Auf finden Sie aktuell 0 Son of Sevenless Homolog 1 (Drosophila) (SOS1) ELISA Kits von unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SOS1 Antikörper (61) und SOS1 Proteine (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 78 SOS1 Produkte verfügbar.
4430401P03Rik, 9630010N06, AI449023, GF1, GGF1, GINGF, HGF, NS4
list all ELISA KIts Gen GeneID UniProt
Human SOS1 SOS1 6654 Q07889
Maus SOS1 SOS1 20662 Q62245
Ratte SOS1 SOS1 313845  

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Weitere ELISA Kits für SOS1 Interaktionspartner

Human Son of Sevenless Homolog 1 (Drosophila) (SOS1) Interaktionspartner

  1. Grb2-independent interactions are sufficient to retain human SOS on the membrane for many minutes, during which a single SOS molecule could processively activate thousands of Ras molecules.

  2. a computational methodology that overlays any variant database onto the somatic mutations in all cancer exomes identified activating SOS1 mutations associated with Noonan syndrome as significantly altered in melanoma

  3. Data show that a heterozygous son of sevenless homolog 1 (SOS1) gene frameshift mutation (c.3266dup or c.3248dup) was identified in each patient.

  4. The present study provides a first evidence of allelic imbalance of SOS1 and pinpoints this condition as a possible mechanism underlying a different penetrance of some SOS1-mutated alleles in unrelated carriers

  5. In non-apoptotic cells, nuclear EGFR (zeige EGFR ELISA Kits) induced SOS1 expression by directly binding to the SOS1 promoter.

  6. findings suggest that targeting the Src (zeige SRC ELISA Kits)/Abl (zeige ABL1 ELISA Kits)/Sos1/Rac (zeige AKT1 ELISA Kits) pathway may represent a double-edged sword to control both cancer-invasive capacities and cancer-related inflammation.

  7. These data demonstrated the negative regulation between miR (zeige MLXIP ELISA Kits)-146a and SOS1 and between miR (zeige MLXIP ELISA Kits)-370 and GADD45beta (zeige GADD45B ELISA Kits) and that these regulations are influenced by enterovirus 71 to induce apoptosis.

  8. Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzyme.

  9. SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1.

  10. HGF (zeige HGF ELISA Kits)-related mutation g.126,142-126,143insC in exon 21 was not found in any of the 6 affected individuals from three families.

Mouse (Murine) Son of Sevenless Homolog 1 (Drosophila) (SOS1) Interaktionspartner

  1. a direct mechanistic link between Sos1 and control of intracellular oxidative stress, and demonstrate functional prevalence of Sos1 over Sos2 with regards to cellular proliferation and viability.

  2. findings suggest that targeting the Src (zeige SRC ELISA Kits)/Abl (zeige ABL1 ELISA Kits)/Sos1/Rac (zeige AKT1 ELISA Kits) pathway may represent a double-edged sword to control both cancer-invasive capacities and cancer-related inflammation.

  3. The increased activity of the PI3K/AKT (zeige AKT1 ELISA Kits) pathway led to downregulation of the surface receptor CD62L (zeige SELL ELISA Kits) in Sos-1/2dKO T cells and a subsequent impairment in T-cell migration.

  4. SUMOylation of Grb2 (zeige GRB2 ELISA Kits) enhances the ERK (zeige EPHB2 ELISA Kits) activity by increasing its binding with Sos1.

  5. Data suggest that interactions between Sos1 (Son of Sevenless homolog 1) and Crk (zeige CRK ELISA Kits) (proto-oncogene (zeige RAB1A ELISA Kits) proteins c-crk (zeige CRK ELISA Kits)) involve electrostatic interactions at binding sites.

  6. ROS1 (zeige ROS1 ELISA Kits) kinase activity and MEK1 (zeige MAP2K1 ELISA Kits)/2-ERK1/2 (zeige MAPK1/3 ELISA Kits) signaling regulates epithelial differentiation in the epididymis.

  7. Sos1 has distinct roles in acting as a scaffold to oligomerize the adaptor protein LAT (zeige LAT ELISA Kits), and in guanine nucleotide exchange activity

  8. ezrin also is important for the activity of SOS itself. Ezrin interacts with GDP-Ras and with the Dbl homology (DH)/pleckstrin homology (PH) domains of SOS, bringing GDP-Ras to the proximity of the allosteric site of SOS.

  9. Absolute counts of mature B and T cells in spleen and peripheral blood were unchanged in single-knockout mutants, while significantly reduced in Sos1/2 double-knockout mice.

  10. Study shows that the ability of Sos1/Grb2 to appropriately regulate pluripotency and differentiation factors and to initiate primitive endoderm development requires collective binding of multiple Sos1/Grb2 domains to their protein and phospholipid ligands.

SOS1 Antigen-Profil

Beschreibung des Gens

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.

Alternative names and synonyms associated with SOS1

  • son of sevenless homolog 1 (Drosophila) (SOS1) Elisa Kit
  • son of sevenless homolog 1 (Drosophila) (Sos1) Elisa Kit
  • Son of sevenless homolog 1 (Drosophila) (Sos1) Elisa Kit
  • 4430401P03Rik Elisa Kit
  • 9630010N06 Elisa Kit
  • AI449023 Elisa Kit
  • GF1 Elisa Kit
  • GGF1 Elisa Kit
  • GINGF Elisa Kit
  • HGF Elisa Kit
  • NS4 Elisa Kit

Bezeichner auf Proteinebene für SOS1

SOS-1 , gingival fibromatosis, hereditary, 1 , guanine nucleotide exchange factor , son of sevenless homolog 1 , guanine nucleotide releasing factor , ras guanine exchange factor , son-of-sevenless 1 , Son of sevenless homolog 1

6654 Homo sapiens
20662 Mus musculus
313845 Rattus norvegicus
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