anti-RYK (RYK) Antikörper

Bezeichnung:
anti-RYK Receptor-Like Tyrosine Kinase Antikörper (RYK)
Auf www.antikoerper-online.de finden Sie aktuell 107 RYK Receptor-Like Tyrosine Kinase (RYK) Antikörper von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RYK Proteine (11) und RYK Kits (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 128 RYK Produkte verfügbar.
Synonyme:
AW536699, D3S3195, ERK-3, JTK5, JTK5A, MGC114645, RYK, RYK1, Vik, wu:fb37b12, wu:fi05b06, zgc:158381

Meistgesuchte Reaktivitäten zu anti-RYK (RYK) Antikörper

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anti-Human RYK Antikörper:

anti-Mouse (Murine) RYK Antikörper:

anti-Rat (Rattus) RYK Antikörper:

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Am meisten referenzierte anti-RYK Antikörper

  1. Human Polyclonal RYK Primary Antibody für EIA, IHC (p) - ABIN359937 : Trivier, Ganesan: RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6. in The Journal of biological chemistry 2002 (PubMed)
    Zeige alle 5 Referenzen für 359937

  2. Human Polyclonal RYK Primary Antibody für EIA, WB - ABIN453358 : Wang, Katso, Butler, Hanby, Poulsom, Jones, Sheer, Ganesan: H-RYK, an unusual receptor kinase: isolation and analysis of expression in ovarian cancer. in Molecular medicine (Cambridge, Mass.) 1996 (PubMed)
    Zeige alle 3 Referenzen für 453358

  3. Human Polyclonal RYK Primary Antibody für IHC (p), WB - ABIN392050 : Miyashita, Koda, Kitajo, Yamazaki, Takahashi, Kikuchi, Yamashita: Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury. in Journal of neurotrauma 2009 (PubMed)
    Zeige alle 2 Referenzen für 392050

  4. Human Polyclonal RYK Primary Antibody für IHC (p), WB - ABIN392051 : Keeble, Halford, Seaman, Kee, Macheda, Anderson, Stacker, Cooper: The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)

  5. Human Monoclonal RYK Primary Antibody für WB - ABIN264516 : Graham, Dawson, Mullaney, Snodgrass, Earp: Cloning and mRNA expression analysis of a novel human protooncogene, c-mer. in Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994 (PubMed)

Weitere Antikörper gegen RYK Interaktionspartner

Zebrafish RYK Receptor-Like Tyrosine Kinase (RYK) Interaktionspartner

  1. RYK and VANGL2 (zeige VANGL2 Antikörper) proteins form a complex, whereas RYK also activated RhoA (zeige RHOA Antikörper), a downstream effector of PCP (zeige PRCP Antikörper) signaling.

  2. Data suggest that full-length Ryk conveys Wnt5b (zeige WNT5B Antikörper) signals in a directional manner during gastrulation.

Human RYK Receptor-Like Tyrosine Kinase (RYK) Interaktionspartner

  1. our findings demonstrate that Ryk promotes stem cell-like and tumorigenic features to glioma cells its essential for the maintenance of glioblastoma stem cells

  2. Wnt5A (zeige WNT5A Antikörper)/Ryk signaling might provide novel therapeutic strategies to prevent capillary leakage in systemic inflammation and septic shock.

  3. results corroborated previous findings of Ryk-mediated Wnt5a (zeige WNT5A Antikörper) effect, and suggested a role for Ror2 (zeige ROR2 Antikörper) in the Wnt5a (zeige WNT5A Antikörper) machinery in glioblastoma

  4. Early treatment with HGF (zeige HGF Antikörper)/IgG complexes after myocardial ischaemia with reperfusion may rescue tissue through vasoprotection conferred by c-Met and RYK signalling

  5. Ryk-intracellular domain pathway may impair FOXO (zeige FOXO3 Antikörper) protective activity in mutant polyglutamine neurons, suggesting neurons unable to efficiently maintain function and resist disease from the earliest phases of the pathogenic process in Huntington disease (zeige HTT Antikörper)

  6. is a candidate wnt5a (zeige WNT5A Antikörper) receptor.

  7. The Ryk is important for the Wnt-5a (zeige WNT5A Antikörper)-dependent induction of MMP-2 (zeige MMP2 Antikörper) and invasive activity in glioma-derived cells and that Ryk might have a novel patho-physiological function in adult cancer invasion.

  8. RYK and VANGL2 (zeige VANGL2 Antikörper) proteins form a complex, whereas RYK also activated RhoA (zeige RHOA Antikörper), a downstream effector of PCP (zeige PRCP Antikörper) signaling.

  9. RYK interacts both physically and functionally with the E3 ubiquitin MIB1. MIB1 is sufficient to activate Wnt (zeige WNT2 Antikörper)/CTNNB1 (zeige CTNNB1 Antikörper) signaling and this activity depends on endogenous RYK.

  10. RYK, a catalytically inactive receptor tyrosine kinase (zeige RET Antikörper), associates with EphB2 (zeige EPHB2 Antikörper) and EphB3 (zeige EPHB3 Antikörper) but does not interact with AF-6 (zeige MLLT4 Antikörper).

Mouse (Murine) RYK Receptor-Like Tyrosine Kinase (RYK) Interaktionspartner

  1. reveal a novel function of Ryk signaling in controlling motor cortex remapping after spinal cord injury in adulthood.

  2. Ryk deficiency in hematopoietic stem cells from fetal liver reduces their quiescence, leading to proliferation-induced apoptosis and decreased self-renewal.

  3. Ryk-intracellular domain pathway may impair FOXO (zeige FOXO3 Antikörper) protective activity in mutant polyglutamine neurons, suggesting neurons unable to efficiently maintain function and resist disease from the earliest phases of the pathogenic process in Huntington disease (zeige HTT Antikörper)

  4. Wnt5a (zeige WNT5A Antikörper) regulates HSC (zeige FUT1 Antikörper) quiescence and hematopoietic repopulation through the Ryk receptor and that this process is mediated by suppression of reactive oxygen species.

  5. Ryk inhibits axonal growth in response to Wnt5a (zeige WNT5A Antikörper).

  6. Ryk is an important mediator of ventral midbrain dopaminergic neuron development.

  7. Ryk regulates Wnt5a (zeige WNT5A Antikörper) signaling and planar cell polarity by modulating the degradation of Vangl2 (zeige VANGL2 Antikörper).

  8. RYK and VANGL2 (zeige VANGL2 Antikörper) proteins form a complex, whereas RYK also activated RhoA (zeige RHOA Antikörper), a downstream effector of PCP (zeige BMP1 Antikörper) signaling.

  9. Results identify Ryk as a multi-functional receptor that is able to transduce extrinsic cues into progenitor cells, promote GABAergic neuron formation, and inhibit oligodendrogenesis during ventral embryonic brain development.

  10. Mammalian Ryk, unlike the Drosophila Ryk homolog Derailed, functions as a coreceptor along with Frizzled for Wnt (zeige WNT2 Antikörper) ligands.

RYK Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with RYK

  • RYK receptor-like tyrosine kinase (RYK) Antikörper
  • ryk receptor-like tyrosine kinase (ryk) Antikörper
  • receptor-like tyrosine kinase (ryk) Antikörper
  • receptor-like tyrosine kinase (RYK) Antikörper
  • RYK receptor-like tyrosine kinase (ryk) Antikörper
  • receptor-like tyrosine kinase (Ryk) Antikörper
  • AW536699 Antikörper
  • D3S3195 Antikörper
  • ERK-3 Antikörper
  • JTK5 Antikörper
  • JTK5A Antikörper
  • MGC114645 Antikörper
  • RYK Antikörper
  • RYK1 Antikörper
  • Vik Antikörper
  • wu:fb37b12 Antikörper
  • wu:fi05b06 Antikörper
  • zgc:158381 Antikörper

Bezeichner auf Proteinebene für RYK

RYK receptor-like tyrosine kinase , tyrosine kinase RYK , ryk receptor-like tyrosine kinase , receptor-like tyrosine kinase , tyrosine-protein kinase RYK , tyrosine kinase-related protein , tyrosine-protein kinase RYK-like , JTK5A protein tyrosine kinase , hydroxyaryl-protein kinase , NYK-R , growth factor receptor , kinase VIK , met-related kinase

GENE ID SPEZIES
395409 Gallus gallus
470931 Pan troglodytes
477074 Canis lupus familiaris
550026 Xenopus (Silurana) tropicalis
558502 Danio rerio
718950 Macaca mulatta
734495 Xenopus laevis
781353 Bos taurus
100008628 Oryctolagus cuniculus
100466026 Ailuropoda melanoleuca
100541106 Meleagris gallopavo
100555132 Anolis carolinensis
100591428 Nomascus leucogenys
6259 Homo sapiens
20187 Mus musculus
140585 Rattus norvegicus
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