anti-PDGFRA (PDGFRA) Antikörper

Bezeichnung:
anti-Platelet-Derived Growth Factor Receptor, alpha Polypeptide Antikörper (PDGFRA)
Auf www.antikoerper-online.de finden Sie aktuell 558 Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antikörper von 31 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PDGFRA Kits (58) und PDGFRA Proteine (38) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 683 PDGFRA Produkte verfügbar.
Synonyme:
AI115593, APDGFR, CD140A, PDGFACE, PDGFR, PDGFR-2, PDGFR-A, PDGFR2, RHEPDGFRA

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Am meisten referenzierte anti-PDGFRA Antikörper

  1. Human Polyclonal PDGFRA Primary Antibody für IHC (p), WB - ABIN392024 : Wilczynski, Chen, Chen, Howell, Shively, Alberts: Expression and mutational analysis of tyrosine kinase receptors c-kit, PDGFRalpha, and PDGFRbeta in ovarian cancers. in Human pathology 2005 (PubMed)
    Zeige alle 5 Referenzen für 392024

  2. Human Polyclonal PDGFRA Primary Antibody für IHC (p), WB - ABIN392029 : Hiwatari, Taki, Tsuchida, Hanada, Hongo, Sako, Hayashi: Novel missense mutations in the tyrosine kinase domain of the platelet-derived growth factor receptor alpha(PDGFRA) gene in childhood acute myeloid leukemia with t(8;21)(q22;q22) or inv(16)(p13q22). in Leukemia 2005 (PubMed)
    Zeige alle 5 Referenzen für 392029

  3. Human Polyclonal PDGFRA Primary Antibody für EIA, IHC (p) - ABIN359912 : Chen, Wang, Huang, Liu: [Experimental study on effects of shengmai injection: enhancing 5-FU anti-tumor efficacy and reducing its toxicity]. in Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 2005 (PubMed)
    Zeige alle 5 Referenzen für 359912

  4. Human Polyclonal PDGFRA Primary Antibody für IHC (p), WB - ABIN392025 : Subramanian, West, Corless, Ou, Rubin, Chu, Leung, Yuen, Zhu, Hernandez-Boussard, Montgomery, Nielsen, Patel, Goldblum, Heinrich, Fletcher, van de Rijn: Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles. in Oncogene 2004 (PubMed)
    Zeige alle 5 Referenzen für 392025

  5. Human Polyclonal PDGFRA Primary Antibody für EIA, IF - ABIN359914 : Debiec-Rychter, Cools, Dumez, Sciot, Stul, Mentens, Vranckx, Wasag, Prenen, Roesel, Hagemeijer, Van Oosterom, Marynen: Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants. in Gastroenterology 2005 (PubMed)
    Zeige alle 5 Referenzen für 359914

  6. Human Polyclonal PDGFRA Primary Antibody für EIA, IHC (p) - ABIN359906 : Cools, DeAngelo, Gotlib, Stover, Legare, Cortes, Kutok, Clark, Galinsky, Griffin, Cross, Tefferi, Malone, Alam, Schrier, Schmid, Rose, Vandenberghe, Verhoef, Boogaerts, Wlodarska, Kantarjian, Marynen et al.: A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. ... in The New England journal of medicine 2003 (PubMed)
    Zeige alle 5 Referenzen für 359906

  7. Human Polyclonal PDGFRA Primary Antibody für IHC (p), WB - ABIN392027 : Sakurai, Hasegawa, Sakuma, Takazawa, Motegi, Nakajima, Saito, Fukayama, Shimoda: Myxoid epithelioid gastrointestinal stromal tumor (GIST) with mast cell infiltrations: a subtype of GIST with mutations of platelet-derived growth factor receptor alpha gene. in Human pathology 2004 (PubMed)
    Zeige alle 5 Referenzen für 392027

  8. Human Polyclonal PDGFRA Primary Antibody für FACS, IHC (p) - ABIN392022 : Andrae, Molander, Smits, Funa, Nistér: Platelet-derived growth factor-B and -C and active alpha-receptors in medulloblastoma cells. in Biochemical and biophysical research communications 2002 (PubMed)

Weitere Antikörper gegen PDGFRA Interaktionspartner

Mouse (Murine) Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Interaktionspartner

  1. FOXA3 (zeige FOXA3 Antikörper) is a marker of the Sertoli cell lineage and of the adult Leydig cell population, and is a regulator of Pdgfra transcription in Leydig cells.

  2. PDGFRalpha and PDGFRbeta are coexpressed in the craniofacial mesenchyme of mid-gestation mouse embryos and that ablation of Pdgfrb (zeige PDGFRB Antikörper) in the neural crest lineage results in increased nasal septum width, delayed palatal shelf development, and subepidermal blebbing.

  3. The results from this study indicate that PDGF (zeige PDGFA Antikörper) signaling is required for fiber hypertrophy, extracellular matrix production, and angiogenesis that occur during muscle growth.

  4. transient middle cerebral-arterial occlusion (MCAO) was introduced into the mice with conditional Pdgfrb (zeige PDGFRB Antikörper)-gene inactivation, including N-PRbeta-KO mice where the Pdgfrb (zeige PDGFRB Antikörper)-gene was mostly inactivated in the brain except that in vascular pericytes

  5. PDGFR alpha has an important role in cranial neural crest cell mitosis within the mandibular processes

  6. PDGF (zeige PDGFA Antikörper) signalling in the dermis and in dermal condensates is dispensable for hair follicle induction and formation.

  7. PDGFRalpha has a role in demarcating the cardiogenic clonogenic Sca1 (zeige ATXN1 Antikörper)+ stem/progenitor cell in adult murine myocardium

  8. In KIT-mutant GIST, inhibition of PDGFRA disrupts a KIT-ERK (zeige EPHB2 Antikörper)-ETV1 (zeige ETV1 Antikörper)-KIT signaling loop by inhibiting ERK (zeige EPHB2 Antikörper) activation.

  9. Ganglioside GD3 enhances invasiveness of gliomas by forming a complex with PDGFRalpha and Yes Kinase (zeige YES1 Antikörper).

  10. Primary high invasive Glioma initiating cells SU3 contribute to transformation of adjacent normal host glial cells in local tumor microenvironment possibly via PDGF (zeige PDGFA Antikörper)/PDGFR (zeige PDGFRB Antikörper) signaling activation.

Human Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Interaktionspartner

  1. Data indicate that co-inhibition of FGFR1 (zeige FGFR1 Antikörper) and HER2 (zeige ERBB2 Antikörper) or PDGFRalpha led to enhanced drug responses.

  2. High PDGFRA expression is associated with pathogenesis of malignant peripheral nerve sheath tumor.

  3. The interaction between CSR1 (zeige SCARA3 Antikörper) and SF3A3 (zeige SF3A3 Antikörper) led to migration of SF3A3 (zeige SF3A3 Antikörper) from nucleus to cytoplasm. The cytoplasmic redistribution of SF3A3 (zeige SF3A3 Antikörper) significantly reduced the splicing efficiency of epidermal growth factor receptor (zeige EGFR Antikörper) and platelet-derived growth factor receptor (zeige PDGFRL Antikörper).

  4. PDGFRa amplification in multiple skin lesions of undifferentiated pleomorphic sarcoma

  5. PDGFRA mutations were associated with gastrointestinal stromal tumors.

  6. The PDGFRA kinase domain structure we report in this study has potential to facilitate development of new agents which can inhibit this kinase, including both its activating and drug-resistant mutations.

  7. BRAF (zeige BRAF Antikörper) mutations are rare events in KIT/PDGFRA wild-type gastrointestinal stromal tumors.

  8. There are two platelet-derived growth factor receptor (PDGFR (zeige PDGFRB Antikörper)) genes (PDGFRA and PDGFRB (zeige PDGFRB Antikörper)), and they reside on chromosome 4 and 5.

  9. Data did not detect any significant association with SNPs of APRIL, SPATA8, PDGFRA, and POLB with Systemic Lupus Erythematosus in Chinese Han Population.

  10. Synchronous T lymphoblastic lymphoma and myeloid neoplasm with PDGFRA rearrangement.

PDGFRA Antigen-Profil

Beschreibung des Gens

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Alternative names and synonyms associated with PDGFRA

  • platelet-derived growth factor receptor, alpha polypeptide (PDGFRA) Antikörper
  • platelet-derived growth factor receptor, alpha polypeptide (LOC100218386) Antikörper
  • platelet derived growth factor receptor, alpha polypeptide (Pdgfra) Antikörper
  • platelet derived growth factor receptor, alpha polypeptide (pdgfra) Antikörper
  • platelet-derived growth factor receptor alpha (LOC100343006) Antikörper
  • AI115593 Antikörper
  • APDGFR Antikörper
  • CD140A Antikörper
  • PDGFACE Antikörper
  • PDGFR Antikörper
  • PDGFR-2 Antikörper
  • PDGFR-A Antikörper
  • PDGFR2 Antikörper
  • RHEPDGFRA Antikörper

Bezeichner auf Proteinebene für PDGFRA

platelet-derived growth factor receptor, alpha polypeptide , alpha-type platelet-derived growth factor receptor-like , Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha) , CD140 antigen-like family member A , PDGF alpha chain , PDGF-R-alpha , PDGFR-alpha , alpha-type platelet-derived growth factor receptor , platelet-derived growth factor alpha receptor , platelet-derived growth factor receptor alpha , alpha platelet-derived growth factor receptor , CD140a antigen , PDGFRA/BCR fusion , platelet-derived growth factor receptor 2 , rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein , tyrosine kinase PDGFR

GENE ID SPEZIES
100059815 Equus caballus
100218386 Taeniopygia guttata
100412331 Callithrix jacchus
100431735 Pongo abelii
100464991 Ailuropoda melanoleuca
18595 Mus musculus
25267 Rattus norvegicus
380245 Xenopus laevis
100343006 Oryctolagus cuniculus
5156 Homo sapiens
442860 Canis lupus familiaris
407607 Sus scrofa
282301 Bos taurus
395509 Gallus gallus
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