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anti-Human PDGFB Antikörper:
anti-Mouse (Murine) PDGFB Antikörper:
anti-Rat (Rattus) PDGFB Antikörper:
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Human Polyclonal PDGFB Primary Antibody für IF (p), IHC (p) - ABIN725990
Morita, Furube, Mannari, Okuda, Tatsumi, Wanaka, Miyata: Vascular endothelial growth factor-dependent angiogenesis and dynamic vascular plasticity in the sensory circumventricular organs of adult mouse brain. in Cell and tissue research 2015
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Human Polyclonal PDGFB Primary Antibody für WB - ABIN3043599
Hong, Hong, Chen, Wang, Hong: Investigation of the protective effect of erythropoietin on spinal cord injury in rats. in Experimental and therapeutic medicine 2012
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Human Polyclonal PDGFB Primary Antibody für IHC (fro), IHC (p) - ABIN115467
Harrison, Kharbanda, Cunningham, McLellan, Hayes: Distribution of glutathione S-transferase isoenzymes in human kidney: basis for possible markers of renal injury. in Journal of clinical pathology 1989
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Human Polyclonal PDGFB Primary Antibody für IHC (fro), IHC (p) - ABIN115468
van Steensel, Paridaens, van Meurs, van Hagen, van den Bosch, Kuijpers, Drexhage, Hooijkaas, Dik: Orbit-infiltrating mast cells, monocytes, and macrophages produce PDGF isoforms that orchestrate orbital fibroblast activation in Graves' ophthalmopathy. in The Journal of clinical endocrinology and metabolism 2012
Human Monoclonal PDGFB Primary Antibody für CyTOF, FACS - ABIN258832
Schito, Rey, Tafani, Zhang, Wong, Russo, Russo, Semenza: Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells. in Proceedings of the National Academy of Sciences of the United States of America 2012
Human Polyclonal PDGFB Primary Antibody für IHC, IHC (p) - ABIN4344540
Hartleben, Widmeier, Suhm, Worthmann, Schell, Helmstädter, Wiech, Walz, Leitges, Schiffer, Huber: aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation. in Journal of the American Society of Nephrology : JASN 2013
Human Polyclonal PDGFB Primary Antibody für IHC, ELISA - ABIN1585009
Lim, Moon, Shin, Kim, Cho, Kim, Park, Choi, Ko, Chung, Lee, Jang, Kim, Park: Effect of S-adenosylmethionine on neointimal formation after balloon injury in obese diabetic rats. in Cardiovascular research 2011
PDAP-1 (zeige PDAP1 Antikörper) as an effecter of PDGF (zeige PDGFA Antikörper) signaling in glioma cells
High PDGFB expression is associated with gastric cancer.
We observed that regenerating and necrotic muscle fibers in muscle biopsy samples from Duchenne muscular dystrophy (zeige DMD Antikörper) patients expressed PDGF (zeige PDGFA Antikörper)-BB.
Elevated PDGFB expression was noted in 29% of patients with papillary renal cell carcinoma (zeige MOK Antikörper).
Insulin (zeige INS Antikörper) treatment caused sustained Akt (zeige AKT1 Antikörper) activity, whereas EGF (zeige EGF Antikörper) or PDGF (zeige PDGFA Antikörper)-AA promoted transient signaling; PDGF (zeige PDGFA Antikörper)-BB produced sustained responses at higher concentrations.Transient responses to EGF (zeige EGF Antikörper) were caused by negative feedback at the receptor level, as a second treatment yielded minimal responses, whereas parallel exposure to IGF-I (zeige IGF1 Antikörper) caused full Akt (zeige AKT1 Antikörper) activation
high-throughput affinity plasma proteomic profiling is a valuable research strategy to identify potential candidate biomarkers for thrombosis-related disorders, and our study suggests a novel association of PDGFB plasma levels with venous thromboembolism.
High PDGFB expression is associated with glioma.
A cell-autonomous positive-signaling circuit is associated with the PDGF (zeige PDGFA Antikörper)-NO-ID4 (zeige ID4 Antikörper)-regulatory axis in glioblastoma cells.
SphK1 (zeige SPHK1 Antikörper) is regulated by PDGF (zeige PDGFA Antikörper)-BB in pulmonary artery smooth muscle cells via the transcription factor Egr-1 (zeige EGR1 Antikörper), promoting cell proliferation.
PDGF (zeige PDGFA Antikörper)-BB regulates the proliferation and differentiation of human melanocytes in a differentiation-stage-specific manner.
intrinsic PDGF-B expressed in the spinal cord may play an essential role in neuroregulation in primates following cord hemisection
hypoxia increased the expression of platelet-derived growth factor (PDGF (zeige PDGFA Antikörper)) and transforming growth factor-beta1 (TGF-beta1 (zeige TGFB1 Antikörper)) and decreased the expression of neprilysin (NEP (zeige MME Antikörper)), which contributed to the hypoxia-induced Endothelial-to-mesenchymal transition of pulmonary artery endothelial cells.
Study suggest that PDGF-B is induced by hypoxia and protects against apoptosis via the PI3K/Akt (zeige AKT1 Antikörper)/Stat3 (zeige STAT3 Antikörper) signaling pathway.
PDGF-B transcription is increased by Nuclear Factor Kappa B
up-regulated by Angiotensin II in retinal pericytes; results suggest that Ang II (zeige AGT Antikörper)-type 1 receptor interaction could stimulate PDGF-B gene expression in cultured retinal pericytes through intracellular reactive oxygen species generation
PEDF promotes growth of pericytes through autocrine production of PDGFB.
Hypoxia enhances PDGF-B paracrine interactions between glomerular endothelial and mesangial cells.
These results demonstrate the requirement of lymphatic endothelial cells-autonomous PDGFB expression and retention for smooth muscle cell recruitment to lymphatic vessels.
Mechanical strain stimulates vasculogenesis of embryonic stem cells by the intracellular messengers ROS (zeige ROS1 Antikörper), NO and calcium as well as by upregulation of angiogenesis guidance molecules and the angiogenic growth factors VEGF (zeige VEGFA Antikörper), FGF-2 (zeige FGF2 Antikörper) and PDGF (zeige PDGFA Antikörper)-BB.
PDGF-B-PDGFRbeta signaling plays a significant role in the development of adipose tissue neovascularization.
data suggest that the stronger fibrotic effect generated by Pdgfa (zeige PDGFA Antikörper) overexpression was mediated by Pdgfralpha in cardiac interstitial mesenchymal cells
loss-of-function mutations in PDGFB or PDGFRB (zeige PDGFRB Antikörper) cause Primary Familial Brain Calcification.
Results suggest that regional Pax3 (zeige PAX3 Antikörper) expression not only marks a novel subset of High-grade Brainstem Glioma but also contributes to PDGF-B-induced brainstem gliomagenesis
High PDGFB expression is associated with liver fibrosis.
Increased expression of STAT5b (zeige STAT5B Antikörper) + PDGFB led to increased expression of downstream STAT5b (zeige STAT5B Antikörper) targets.
Platelets produce PDGFB to activate stellate cells and promote fibrosis in MDR2 (zeige ABCB4 Antikörper)-null mice.
The endogenous levels of PDGF (zeige PDGFA Antikörper)-BB, increases CD31 (zeige PECAM1 Antikörper)(hi)endomucin (zeige EMCN Antikörper)(hi) vessel number and stimulates bone formation in ovariectomy mice.
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
PDGF subunit B
, PDGF, B chain
, platelet-derived growth factor 2
, platelet-derived growth factor B chain
, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
, platelet-derived growth factor subunit B
, platelet-derived growth factor, beta polypeptide (oncogene SIS)
, proto-oncogene c-Sis
, platelet-derived growth factor B
, v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog)
, platelet-derived growth factor beta polypeptide
, Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis)
, pdgf protein
, platelet derived growth factor, B polypeptide
, platelet-derived growth factor B subunit