anti-MCK10 (DDR1) Antikörper

Bezeichnung:
anti-Discoidin Domain Receptor Family, Member 1 Antikörper (DDR1)
Auf www.antikoerper-online.de finden Sie aktuell 19 Discoidin Domain Receptor Family, Member 1 (DDR1) Antikörper von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MCK10 Proteine (5) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 29 MCK10 Produkte verfügbar.
Synonyme:
6030432F18, AI323681, CAK, CD167, CD167a, DDR, DDR1, Drd1, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, PTK3D, RTK6, TRKE
Alle Antikörper anzeigen Gen GeneID UniProt
DDR1 12305 Q03146
DDR1 780 Q08345
DDR1 25678  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-MCK10 (DDR1) Antikörper

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anti-Mouse (Murine) MCK10 Antikörper:

anti-Human MCK10 Antikörper:

anti-Rat (Rattus) MCK10 Antikörper:

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Am meisten referenzierte anti-MCK10 Antikörper

  1. Human Polyclonal MCK10 Primary Antibody für EIA, IHC (p) - ABIN359899 : Vogel, Gish, Alves, Pawson: The discoidin domain receptor tyrosine kinases are activated by collagen. in Molecular cell 1998 (PubMed)
    Zeige alle 5 Referenzen für 359899

  2. Human Monoclonal MCK10 Primary Antibody für FACS - ABIN2663088 : Di Marco, Cutuli, Guerra, Cancedda, De Luca: Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues. in The Journal of biological chemistry 1993 (PubMed)
    Zeige alle 5 Referenzen für 2663088

  3. Human Monoclonal MCK10 Primary Antibody für FACS - ABIN2664284 : Hou, Vogel, Bendeck: The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair. in The Journal of clinical investigation 2001 (PubMed)
    Zeige alle 4 Referenzen für 2664284

  4. Human Monoclonal MCK10 Primary Antibody für WB - ABIN1105935 : Foehr, Tatavos, Tanabe, Raffioni, Goetz, Dimarco, De Luca, Bradshaw: Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000 (PubMed)
    Zeige alle 3 Referenzen für 1105935

Weitere Antikörper gegen MCK10 Interaktionspartner

Mouse (Murine) Discoidin Domain Receptor Family, Member 1 (DDR1) Interaktionspartner

  1. DDR-1 interacts with the TGF-beta (zeige TGFB1 Antikörper) pathway to restrict calcifying extracellular vesicle-mediated mineralization and fibrosis by smooth muscle cells.

  2. alpha5(IV), but not alpha1(IV), promotes lung cancer cell proliferation and tumor angiogenesis through non-integrin collagen receptor (zeige ITGA2 Antikörper) DDR1-mediated ERK (zeige EPHB2 Antikörper) activation.

  3. DDR1 malfunction causes outer hair cells deformation and the separation of the lateral wall, the location of the cellular motor responsible for the electromotile property, explicitly in those regions showing DDR1 and NM-IIA co-localization.

  4. the collagen receptors DDR1 and integrin a2b1 contribute to regulate GBM-maturation and to control matrix accumulation.

  5. Extensive co-localization and relationship of Jag1 (zeige JAG1 Antikörper) and Ddr1 in bile ducts and blood vessels in postnatal liver.

  6. Genetic inhibition of discoidin domain receptor 1 protects mice against crescentic glomerulonephritis.

  7. Data identifyies Syk (zeige SYK Antikörper) as a potent inhibitor of epithelial migration and describes a first functional consequence of the interaction with the collagen receptor (zeige ITGA2 Antikörper) DDR1.

  8. Results show that DDR1 promotes cell-cell adhesion and differentiation through stabilization of E-cadherin (zeige CDH1 Antikörper), which is mediated by Cdc42 (zeige CDC42 Antikörper) inactivation.

  9. Collagen I stimulates the self-renewal of embryonic stem cells mediated by Bmi-1 (zeige BMI1 Antikörper) through alpha2beta1 integrin-dependent ILK (zeige ILK Antikörper), Notch (zeige NOTCH1 Antikörper), Gli-1 (zeige GLI1 Antikörper), and DDR1-dependent Ras, PI3K/Akt (zeige AKT1 Antikörper), and ERK (zeige EPHB2 Antikörper).

  10. Loss of Discoidin domain receptor 1 is associated with inflammation and fibrosis in obstructive nephropathy

Human Discoidin Domain Receptor Family, Member 1 (DDR1) Interaktionspartner

  1. This study suggested that DDR1 and DDR2 (zeige DDR2 Antikörper) knockdown alters brain immunity and significantly reduces the level of triggering receptor expressed on myeloid cells (TREM)-2 (zeige TREM2 Antikörper) and microglia.

  2. Isoform b of DDR1 is responsible for collagen I-induced up-regulation of N-cadherin (zeige CDH2 Antikörper) and tyrosine 513 of DDR1b is necessary.

  3. Reduced DDR1 expression may be implicated in impaired melanocyte adhesion process involved in vitiligo (zeige MITF Antikörper) pathogenesis

  4. data demonstrate that TGF-beta1 (zeige TGFB1 Antikörper) favors linear invadosome formation through the expressions of both the inducers, such as collagen and LOXL2 (zeige LOXL2 Antikörper), and the components such as DDR1 and MT1-MMP (zeige MMP14 Antikörper) of linear invadosomes in cancer cells. Meanwhile, our data uncover a new TGF-beta1 (zeige TGFB1 Antikörper)-dependent regulation of DDR1 expression.

  5. DDR1 overexpression promoted GC cell proliferation (p < 0.05), migration (p < 0.01), and invasion (p < 0.01), and accelerated the growth (p < 0.05) as well as the microvessel formation (p < 0.01) of transplantation tumor in nude mice.

  6. Our results suggest that DDR1 is both a prognostic marker for renal clear cell carcinoma and a potential functional target for therapy

  7. Study concludes that non-canonical DDR1 signaling enables breast cancer cells to exploit the ubiquitous interstitial matrix component collagen I to undergo metastatic reactivation in multiple target organs.

  8. Upregulation of DDR1 collagen receptor (zeige ITGA2 Antikörper) is associated with breast cancer.

  9. Knockdown DDR1 reversed the effects of Galpha13 (zeige GNA13 Antikörper) knockdown on cell-cell adhesion and proteolytic invasion in three-dimensional collagen.

  10. Data suggest SCl2 (Streptococcus pyogenes) binds to DDR (DDR1, DDR2 (zeige DDR2 Antikörper)) ectodomain w/o stimulating receptor signaling; here, protein engineering was used to construct SCl (zeige KRT7 Antikörper)-like proteins that inhibit collagen-DDR interactions and macrophage migration.

MCK10 (DDR1) Antigen-Profil

Beschreibung des Gens

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with MCK10 (DDR1)

  • discoidin domain receptor tyrosine kinase 1 (DDR1) Antikörper
  • discoidin domain receptor family, member 1 (ddr1) Antikörper
  • discoidin domain receptor family, member 1 (Ddr1) Antikörper
  • discoidin domain receptor tyrosine kinase 1 (Ddr1) Antikörper
  • 6030432F18 Antikörper
  • AI323681 Antikörper
  • CAK Antikörper
  • CD167 Antikörper
  • CD167a Antikörper
  • DDR Antikörper
  • DDR1 Antikörper
  • Drd1 Antikörper
  • EDDR1 Antikörper
  • HGK2 Antikörper
  • MCK10 Antikörper
  • NEP Antikörper
  • NTRK4 Antikörper
  • PTK3 Antikörper
  • PTK3A Antikörper
  • PTK3D Antikörper
  • RTK6 Antikörper
  • TRKE Antikörper

Bezeichner auf Proteinebene für DDR1

discoidin domain receptor family, member 1 , discoidin domain receptor tyrosine kinase 1 , epithelial discoidin domain-containing receptor 1 , CD167 antigen-like family member A , cell adhesion kinase , discoidin receptor tyrosine kinase , epithelial discoidin domain receptor 1 , protein-tyrosine kinase MPK-6 , tyrosine kinase DDR , tyrosine-protein kinase CAK , PTK3A protein tyrosine kinase 3A , mammary carcinoma kinase 10 , neuroepithelial tyrosine kinase , neurotrophic tyrosine kinase, receptor, type 4 , protein-tyrosine kinase RTK-6 , neurotrophic tyrosine kinase receptor type 4 , protein-tyrosine kinase 3 , protein-tyrosine kinase PTK-3

GENE ID SPEZIES
474832 Canis lupus familiaris
534092 Bos taurus
714233 Macaca mulatta
100007346 Danio rerio
100144462 Sus scrofa
12305 Mus musculus
780 Homo sapiens
25678 Rattus norvegicus
Ausgewählte Anbieter für anti-MCK10 (DDR1) Antikörper
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