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the missense mutation p.Arg682His, the g.77784972T>C variant at KIT and the g.20147039C>T variant at MITF (zeige MITF ELISA Kits) are the main influence on the extent of white facial markings
Accumulating mutations in series of haplotypes at the KIT and MITF (zeige MITF ELISA Kits) loci are major determinants of white markings in Franches-Montagnes horses.
FGF7 (zeige FGF7 ELISA Kits) may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG (zeige KITLG ELISA Kits) signaling pathway.
c-kit is primarily expressed in the spermatogonia and spermatocytes of goat testes.
mRNA expression of c-kit and SCF was decreased in gallbladder tissues in the HCD group. Consistent with the findings of RT-PCR, a lower expression level of c-kit and SCF protein was also observed in HCD animals.
Delayed enrichment for c-kit and inducing cardiac differentiation attenuated protective effects of BMSCs' transplantation in pig model of acute myocardial infarction.
Pravastatin improves function in hibernating myocardium by mobilizing CD133+ and cKit+ bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle.
Long-term follow-up of patients with metastatic GIST treated with regorafenib suggests particular benefit among patients with primary KIT exon 11 mutations and those with SDH (zeige SARDH ELISA Kits)-deficient GIST. Dose modifications are frequently required to manage treatment-related toxicities
c-kit-positive cells derived from right atrium tissue were associated with serum BNP
For hot spots in KIT and PDGFRA (zeige PDGFRA ELISA Kits) genes, 23 out of 146 KIT/PDGFRA (zeige PDGFRA ELISA Kits) wild-type cases carried mutations according to next-generation sequencing (NGS).
KIT and DNMT1 (zeige DNMT1 ELISA Kits) co-expression promotes, whereas dual inactivation of them suppresses, lung cancer cell proliferation and metastatic growth in vitro and in vivo, in a synergistic manner.
Data indicate that BRAF (zeige BRAF ELISA Kits), NRAS (zeige NRAS ELISA Kits) and C-KIT melanomas constitute distinct clinico-pathological entities.
our data established CD117 as a direct target of miR (zeige MLXIP ELISA Kits)-34-5p and demonstrated that this regulation interferes with several CD117-mediated effects on osteosarcoma cells
Results indicate anthraquinone derivative AQ1 as a promising compound for the target therapy of c-KIT-dependent tumors.
Data show that afatinib resistant clones were selectively killed by knock down of ERBB3 (zeige ERBB3 ELISA Kits) + c-MET + c-KIT, but not by the individual or doublet knock down combinations, and the combination of afatinib with the SRC (zeige SRC ELISA Kits) family inhibitor dasatinib killed afatinib resistant H1975 cells in a greater than additive fashion.
Podocalyxin-like protein 1 (zeige PODXL ELISA Kits) is a relevant marker for human c-kit(pos) cardiac stem cells.(
High fertilization (56.06%) and pregnancy (41.7%) rates accomplished in this study following ICSI-AOA (zeige APTX ELISA Kits) indicated that expression profiles of PLCzeta (zeige PLCz1 ELISA Kits), PAWP (zeige WBP2NL ELISA Kits), and TR-KIT were low in globozoospermic individuals
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
c-kit receptor tyrosine kinase
, mast/stem cell growth factor receptor
, protein kinase
, tyrosine kinase receptor homolog
, c-kit-related protein
, kit-related kinase 1
, mast/stem cell growth factor receptor-related protein Kit
, proto-oncogene tyrosine-protein kinase Kit-related protein
, tyrosine-protein kinase Kit
, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
, Mast/stem cell growth factor receptor
, mast/stem cell growth factor receptor Kit
, transmembrane tyrosine kinase receptor
, proto-oncogene c-Kit
, c-kit receptor
, mast cell growth factor receptor
, proto-oncogene tyrosine-protein kinase Kit
, receptor tyrosine kinase c-kit
, c-KIT gene1
, Proto-oncogene c-Kit
, Tyrosine-protein kinase Kit
, caprine c-kit protein
, p145 c-kit
, piebald trait protein
, soluble KIT variant 1
, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein