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Rat (Rattus) IGF1 ELISA Kit für Sandwich ELISA - ABIN416242
Al-Massadi, Trujillo, Señaris, Pardo, Castelao, Casanueva, Seoane: The vagus nerve as a regulator of growth hormone secretion. in Regulatory peptides 2010
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Human IGF1 ELISA Kit für Sandwich ELISA - ABIN625003
Aucouturier, Thivel, Isacco, Fellmann, Chardigny, Duclos, Duché: Combined food intake and exercise unmask different hormonal responses in lean and obese children. in Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme 2013
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Rat (Rattus) IGF1 ELISA Kit für Sandwich ELISA - ABIN411285
Ozdemir, Baykara, Aksu, Kiray, Sisman, Cetin, Dayi, Gurpinar, Uysal, Arda: Relationship between circulating IGF-1 levels and traumatic brain injury-induced hippocampal damage and cognitive dysfunction in immature rats. in Neuroscience letters 2012
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Human IGF1 ELISA Kit für Sandwich ELISA - ABIN365302
A Hamid, Mohamed Ali, Yusof, George: Platelet-rich plasma (PRP): an adjuvant to hasten hamstring muscle recovery. A randomized controlled trial protocol (ISCRTN66528592). in BMC musculoskeletal disorders 2012
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Human IGF1 ELISA Kit für Sandwich ELISA - ABIN414866
Serafín, Agüí, Yáñez-Sedeño, Pingarrón: Electrochemical immunosensor for the determination of insulin-like growth factor-1 using electrodes modified with carbon nanotubes-poly(pyrrole propionic acid) hybrids. in Biosensors & bioelectronics 2013
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Mouse (Murine) IGF1 ELISA Kit für Sandwich ELISA - ABIN415497
Señarís, Trujillo, Navia, Comes, Ferrer, Giralt, Hidalgo: Interleukin-6 regulates the expression of hypothalamic neuropeptides involved in body weight in a gender-dependent way. in Journal of neuroendocrinology 2011
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Dog (Canine) IGF1 ELISA Kit für Sandwich ELISA - ABIN414190
Ciftci, Yarim: Evaluation of IGF-I levels and serum protein profiles of diabetic cats and dogs. in Journal of veterinary science 2011
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Cow (Bovine) IGF1 ELISA Kit für Competition ELISA - ABIN364595
Varughese, Brar, Honparkhe, Ghuman: Correlation of blood flow of the preovulatory follicle to its diameter and endocrine profile in dairy buffalo. in Reproduction in domestic animals = Zuchthygiene 2014
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Rat (Rattus) IGF1 ELISA Kit für Sandwich ELISA - ABIN365381
Tseng, Sung, Chen, Lai, Chang, Sung, Wang: Comparison of chemical compositions and osteoprotective effects of different sections of velvet antler. in Journal of ethnopharmacology 2013
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Mouse (Murine) IGF1 ELISA Kit für Sandwich ELISA - ABIN612799
Sandberg-Nordqvist, Ståhlbom, Reinecke, Collins, von Holst, Sara: Characterization of insulin-like growth factor 1 in human primary brain tumors. in Cancer research 1993
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Enhancing IGF-1 expression by astrocytes provided hippocampal neuroprotection and improved memory and motor function after traumatic brain injury. Delivering IGF-1 through reactive astrocytes targeted IGF-1 overexpression to the damaged hippocampus, producing a progressive increase in IGF-1 over 72 h which led to activation of the Akt (zeige AKT1 ELISA Kits) pro-survival pathway and reduced hippocampal neuron loss in multiple regions.
IGF-1 signaling is essential for sustaining cancer cell viability by stimulating both mitochondrial biogenesis and turnover through BNIP3 (zeige BNIP3 ELISA Kits) induction. This core mitochondrial protective signal is likely to strongly influence responses to therapy and the phenotypic evolution of cancer.
Enhanced study of the role of IIS pathway and epigenetic mechanisms that regulate aging may facilitate progressive prevention and treatment of human age-related diseases.
Insulin (zeige INS ELISA Kits)-Like Growth Factor System in Articular Cartilage
This study explores the prognostic effect of MET, MET gene copy number, polysomy of chromosome 7, IGF1R (zeige IGF1R ELISA Kits) gene copy number and IGF-1 expression in tumor epithelial cells of primary non-small-cell lung cancer in 326 patients.
Low IGF1 expression is associated with low bone mineral density in patients with type 1 diabetes.
Data show that supplementation with selenium and coenzyme Q10 (zeige EIF2C2 ELISA Kits) over four years resulted in increased levels of IGF-1 and the postprandial IGFBP-1 (zeige IGFBPI ELISA Kits).
Results provide evidence that cathepsin G (zeige CTSG ELISA Kits) (GC) activates IGF-1R (zeige IGF1R ELISA Kits) by stimulating IGF-1 release from MCF-7 cells, and that IGF-1R (zeige IGF1R ELISA Kits) activation is required for CG-induced cell aggregation.
We found that the thyroid hormone receptor (zeige THRA ELISA Kits) (TRalpha (zeige THRA ELISA Kits) 3) has a differential expression profile. Thyroid hormone (zeige PTH ELISA Kits) is critical for normal brain development. Our results showed that there is a possible link between IGF1/IGF1R (zeige IGF1R ELISA Kits) and the TRalpha (zeige THRA ELISA Kits) 3 and that over expression of IGF1R (zeige IGF1R ELISA Kits) in RTT cells may be the cause of neurites improvement in neural RTT-derived neurons.
Increased IGF1 level as associated with decreased risk of frailty in men.
The specific aim of the present work was to study whether the partial IGF-1 deficiency influences heart and/or coronary circulation, comparing vasoactive factors before and after of ischemia-reperfusion (I/R).
Data (including data from studies using heterozygous transgenic mice) suggest that gene expression in liver is altered in a model of inflammation of liver due to partial deficiency of Igf1; this leads to over-expression of Igf1 receptor, inflammation mediators, and acute-phase proteins, but under-expression of cytoskeletal proteins, extracellular matrix proteins, and tight junction proteins.
Findings indicate that the energy-sensing LKB1 (zeige STK11 ELISA Kits)-AMPK (zeige PRKAA1 ELISA Kits) pathway regulates IGF1 secretion in mouse primary hepatocytes, which in turn regulates activation of the IGF1R (zeige IGF1R ELISA Kits)-PKB (zeige AKT2 ELISA Kits) pathway.
These results demonstrate that a greater than additive effect is observed on the growth of skeletal muscle and in the reduction of body fat when myostatin (zeige MSTN ELISA Kits) is absent and IGF1 is in excess, and that myostatin (zeige MSTN ELISA Kits) and IGF1 regulate skeletal muscle size, myofibre type and gonadal fat through distinct mechanisms.
Confirmation of the impairment of GH-IGF-1 release in hyperphagic MC4R (zeige MC4R ELISA Kits) KO mice suggests a role for insulin (zeige INS ELISA Kits) in regulating both the release of GH, but also in mediating growth during periods of physiologically suppressed GH-IGF-1 levels
These results indicate that IGF-1 plays a critical role in spermatogenesis from SSCs.
Exercise negatively regulates IGF-1 pathway in skin epidermis.
A role for IGF-1 in axon elongation that appears to be cell selective and participates in the complex cellular mechanisms that link underfeeding during the early postnatal period with programming of the growth trajectory.
These findings demonstrate that the AMPK (zeige PRKAA1 ELISA Kits)-TBC1D1 (zeige TBC1D1 ELISA Kits) signaling nexus interacts with the PKB (zeige AKT2 ELISA Kits)-mTOR (zeige FRAP1 ELISA Kits) pathway via IGF1 secretion, which consequently controls expression of lipogenic genes in the adipose tissue
The immunoprecipitation results also showed that high AA concentrations significantly increased the interaction of mTOR (zeige FRAP1 ELISA Kits) and PPARg (zeige PPARG ELISA Kits). In summary, PPARg (zeige PPARG ELISA Kits) plays an important role in the regulation of IGF-1 secretion and gene expression in response to dietary protein.
Data suggest that both ovarian follicular dominance in cows and cooperation of ovarian follicles in pigs can be mediated by either down- or up-regulation of the insulin-like growth factor 1/oxytocin system.
This study demonstrated that Up-regulation of IGF-1 in the frontal cortex of piglets exposed to an environmentally enriched arena.
Combined administration of mesenchymal stem cells overexpressing IGF-1 and HGF (zeige HGF ELISA Kits) enhances neovascularization but moderately improves cardiac regeneration in a porcine model.
Results show that expression changes of IGF1 genes were associated with C/EBP (zeige CEBPA ELISA Kits) b expression during embryonic and postnatal development in porcine liver.
genetic association study suggests that the TC genotype of IGF-1 represents the selection genotype for smaller in size.
IGF-I coordinately regulates multiple cell signaling pathways that are critical to proliferation, migration and survival of trophectoderm cells during early pregnancy in pigs.
IGF-1 splice variant (mechano growth factor) is expressed within the growth plate, but the addition of its peptides was not associated with growth plate chondrocytes proliferation.
alpha-linolenic acid increased IGF-I secretion from hepatocytes.
Copper can stimulate chondrocyte proliferation by promoting the expression of IGF-1.
Data suggest caloric restriction modifies response of ovarian granulosa cells to leptin (zeige LEP ELISA Kits) on cell proliferation/apoptosis, MAP kinase (zeige MAPK1 ELISA Kits) signaling, and release of hormones (estradiol and IGFI). The caloric restriction studies were conducted in rabbits; then, isolated rabbit granulosa cells were exposed to recombinant human leptin (zeige LEP ELISA Kits). (IGF1 = insulin-like growth factor I)
Intraplacental gene therapy with Ad-IGF-1 corrects naturally occurring rabbit model of intrauterine growth restriction.
Our studies demonstrate that the active SVCT2 (zeige SLC23A2 ELISA Kits) is expressed in IVD (zeige IVD ELISA Kits) cells and that the expression of this transporter is regulated by growth factors IGF-1 and dexamethasone.
increased endogenous IGF1 and IGF2 expression by the blastocyst compensates for the loss of systemic insulin (zeige INS ELISA Kits) and IGF.
IGF1 showed a significantly higher capacity to form the posterior mesoderm and primitive streak (stage 2 and 3) than blastocysts cultured without growth factors
Overall, IGF-1 promoted atherosclerosis by affecting endothelial function and aging.
Findings show similar regulatory growth hormone (GH (zeige GH1 ELISA Kits)) and insulin-like growth factor 1 (IGF-1) responses in both Atlantic salmon and rainbow trout.
the present study assessed the combined impacts of estrogens and bacterial infection on the insulin (zeige INS ELISA Kits)-like growth factors (IGF) and tumor-necrosis factor (TNF)-alpha (zeige TNF ELISA Kits).
Nutrient availability, IGF-I, and genetic variation affect weight loss, in part through alterations of proteolytic pathways in rainbow trout.
Study demonstrated that IGF-I can stimulate egfr (zeige EGFR ELISA Kits) expression in both follicles cell culture and intact follicles promoting oocyte maturation.
IGF-I-induced kitlga expression is inhibited by epidermal growth factor (zeige EGF ELISA Kits), an oocyte-derived paracrine factor in the zebrafish follicle.
hypoxia causes PGC (zeige PGC ELISA Kits) migration defect by inhibiting IGF signaling through the induction of IGFBP-1 (zeige IGFBPI ELISA Kits)
Whereas hypoxia repressed the Igf1 receptor and its downstream Erk1/2 (zeige MAPK1/3 ELISA Kits) and Akt (zeige AKT1 ELISA Kits) signaling activities, re-oxygenation restored their activities
IGF signalling influences expression of BMP2b (zeige BMP4 ELISA Kits), a gene that plays an important role in zebrafish pattern formation
The insulin-like growth factor 1 gene can be differentially transcribed to yield two distinct IGF-1 mRNA transcripts
zebrafish XBP-1 (zeige XBP1 ELISA Kits) spliced form not only activates genes responsible for protein folding, transporting, glycosylation and Endoplasmic Reticulum associated degradation but also activates anti-apoptosis signal via IGF1/Akt (zeige AKT1 ELISA Kits) pathway in unfolded protein
Thus CR suppresses the hypertrophic PGC1alpha-4/IGF-1/AKT1 pathway while promoting activation of the calpain system.
IGF1 single nucleotide polymorphisms associated with milk fatty acids in a Chinese Holstein cattle.
It has been shown that several specific genes which are differentially regulated, including IGF-1, might impact dairy fertility.
There was no association between the genotypes of GH and IGF-IS and fertility of Holstein cows raised in semiextensive or intensive regimes, while the STAT5 (zeige STAT5A ELISA Kits) ABstEII polymorphism was associated with calving-first heat interval in Holstein cows raised in the intensive system.
Associations between genetic variants in the promoter region of the insulin-like growth factor-1 (IGF1) gene and blood serum IGF1 concentration in Hanwoo cattle.
The association of IGF1, GH, and PIT1 (zeige POU1F1 ELISA Kits) markers with growth and reproductive traits were assessed.
These findings strongly support the concept that IGF-1 upregulates LHR (zeige LHCGR ELISA Kits) expression in granulosa cells and that IGF-1 is required for determining which follicle becomes dominant and acquires ovulatory capacity.
Insulin (zeige INS ELISA Kits)-induced glucose uptake in lactating bovine mammary epithelial cells may involve the phosphatidylinositide 3-kinase- but not mitogen-activated protein kinase (zeige MAPK1 ELISA Kits)-mediated signaling pathways.
Data show that individuals with insulin-like growth factor I (IGF-1) allele C had a significantly higher performance in production traits.
Data suggest that metabolism of IGF1, IGF2, and IGFBP3 (insulin-like growth factor binding protein-3 (zeige IGFBP3 ELISA Kits)) can be altered by dietary modifications (here, long-term caloric restriction in Welsh Pony mares).
The laminar cell types expressing insulin receptor (zeige INSR ELISA Kits) and/or insulin-like growth factor-1 receptor (zeige IGF1R ELISA Kits) and the effect of dietary carbohydrates on their expression are reported.
Increased expression of IGF-1 in female equine embryos. Sex-related influences on expression of the IGF system are probably related to a gradual X chromosome inactivation.
Somatomedin (IGF-I) is localized in equine spermatogenic and Leydig cells, and IGF-I receptor (zeige IGF1R ELISA Kits) is present in spermatogonia, spermatocytes and Leydig cells.
Hsp90 (zeige HSP90AB1 ELISA Kits) inhibitor geldanamycin is used to assess age-related responses with IGF1 stimulation of chondrocytes.
Local IGF-1 might play a role in the lesion- and deafness-induced plasticity in FC and at AN/FC synapse following chronic kanamycin-induced deafness.
These results suggest the significant influence of the IGF1 gene on prolificacy in goats and identified SNPs would benefit the selection of prolific animals in future breeding programs.
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
, insulin-like growth factor 1
, insulin-like growth factor I
, insulin-like growth factor IA
, insulin-like growth factor IB
, mechano growth factor
, somatomedin C
, insulin-like growth factor-1
, Insulin-like growth factor I
, class 1 insulin-like growth factor I preproprotein
, insulin growth factor-1
, insulin like growth factor 1
, insulin-like growth factor I (somatomedin C)
, insulin-like growth factor I variant 1
, insulin like growth factor-1
, insulin-like growth factor-I