HGF Proteine (HGF)

Auf www.antikoerper-online.de finden Sie aktuell 82 Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Proteine von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen HGF Antikörper (261) und HGF Kits (121) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 481 HGF Produkte verfügbar.
Synonyme:
AI838057, c-Met, C230052L06Rik, DFNB39, F-TCF, HGF, HGF/SF, HGFB, HGFR, HPTA, NK1, NK2, Par4, SF, SF/HGF
alle Proteine anzeigen Gen GeneID UniProt
HGF 15234 Q08048
HGF 24446 P17945
HGF 3082 P14210

HGF Proteine (HGF) nach Spezies

Weitere Proteine zu HGF Interaktionspartnern

Mouse (Murine) Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Interaktionspartner

  1. a c-Met/ETS-1 (zeige ETS1 Proteine)/matrix metalloproteinase-14 (MMP-14 (zeige MMP14 Proteine)) axis that controls VE-cadherin (zeige CDH5 Proteine) degradation, endothelial mesenchymal transition, and vascular abnormality.

  2. Our results show that BMF (zeige BMF Proteine)-derived IL-6/HGF and cancer cell-derived TGF-b1 mediate the interactions between bone marrow-derived myofibroblasts and gastric cancer cells, which regulate cancer stemness and promote tumorigenesis.

  3. We found the roles of hepatocyte growth factor (HGF) signaling in stria vascularis development for the first time and that lack of HGF signaling in the inner ear leads to profound hearing loss in the mouse. Our findings reveal a novel mechanism that may underlie human deafness DFNB39 and DFNB97. Our findings reveal an additional example of context-dependent c-MET signaling diversity, required here for proper cellular inva

  4. c-Met has been found to attenuate lung injury and apoptosis in bronchial epithelial cells.

  5. this study demonstrates an important role for HGF in the protective effects mediated by mesenchymal stromal cells in vivo in the bleomycin model of idiopathic pulmonary fibrosis

  6. In this paper, we demonstrate a potential biochemical mechanism for such phenomena by showing that c-Met receptors promote the tyrosine phosphorylation of RalGDS (zeige RALGDS Proteine) at Y752 in its RBD (zeige CACNA1D Proteine), which blocks the binding of Ras to RalGDS (zeige RALGDS Proteine).

  7. HGF displays an antioxidant response by inducing the glutathione-related protection system.

  8. this study revealed that HB-EGF (zeige HBEGF Proteine) as well as HGF inhibited BDL-induced cholestatic liver injury by predominantly exerting acute cytoprotective and chronic antifibrotic effects, respectively.

  9. The results suggest that PGRN (zeige GRN Proteine) may affect the differentiation of retinal precursor cells to photoreceptor cells through the HGF receptor signaling pathway.

  10. study demonstrates that co-activation of AKT (zeige AKT1 Proteine) and c-Met induces hepatocellular carcinoma development that depends on the mTORC1/FASN (zeige FASN Proteine) pathway.

Human Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Interaktionspartner

  1. Data suggest that HGF, IL-20 (zeige IL20 Proteine), and IL-22 (zeige IL22 Proteine) in the serum and bronchoalveolar lavage fluid (BALF) of non-small cell lung cancer (NSCLC) patients before chemotherapy may be a prognostic of cancer progression.

  2. Studies indicate that the over-expression of hepatocyte growth factor (HGF) is valuable in colorectal cancer (CRC (zeige CALR Proteine)) prognosis.

  3. These results establish HGF/C-Met as a central organizing signal in blood vessel-directed tumor cell migration in vivo and highlight a promising role for C-Met inhibitors in blocking tumor cell streaming and metastasis in vivo, and for use in human trials.

  4. Furthermore, activation of HGF/Met signaling increased the expression and transcriptional activity of FOXM1 (zeige FOXM1 Proteine), and the cross talk between FOXM1 (zeige FOXM1 Proteine) and HGF/Met signaling promoted pancreatic ductal adenocarcinoma (PDA)growth and resistance to Met inhibition

  5. These data suggest that paxillin (zeige PXN Proteine) appears to influence major cell functions in a diverse range of prostate and breast cancer models. The responsiveness of cells to environmental factors such as HGF or BME may be influenced by paxillin (zeige PXN Proteine) status, although this seems to be dependent on cell type

  6. Fibronectin (zeige FN1 Proteine) and Hepatocyte Growth Factor were shown to be produced by lung fibroblasts and, furthermore, to enhance malignant pleural mesothelioma cell migration and invasion

  7. Glioblastoma patients with high expression of hepatocyte growth factor or unmethylated O(6)-methylguanine-DNA methyltransferase (zeige MGMT Proteine) may benefit from onartuzumab plus bevacizumab chemotherapy.

  8. Plasma levels of HGF in PAH patients with mild disease were significantly higher than those in healthy controls, suggesting that plasma HGF has potential utility as a diagnostic biomarker for early PAH.

  9. Blood HGF was significantly higher in chronic hepatitis C patients with liver fibrosis compared to those without fibrosis.

  10. In summary, a decrease in VEGF-A (zeige VEGFA Proteine) and an increase in sVEGFR1 during chemotherapy and bevacizumab exposure can contribute to both chemotherapy (due to c-MET/b-catenin activation) and bevacizumab (due to low VEGF (zeige VEGFA Proteine) requirements) resistance. Because HGF levels decrease also during acquired resistance, alternative strategies to HGF-ligand inhibition should be investigated

Rabbit Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Interaktionspartner

  1. acute pulmonary embolism associated with an enhanced HGF expression in the lungs, the right ventricle, and the liver

Cow (Bovine) Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Interaktionspartner

  1. SNPs within bovine HGF gene were significantly associated with growth traits. This will provide a background for application of bovine HGF gene in the selection program in Chinese cattle.

  2. Treatment of the bovine satellite cells (BSC (zeige SLC12A2 Proteine)) with ephrin-A5 (zeige EFNA5 Proteine) causes a reduction in velocity with a concomitant increase in directed migration. Treatment of BSC (zeige SLC12A2 Proteine) with hepatocyte growth factor had no immediate effect on cell motility or migration.

  3. HGF transiently increases gene transcription of angiotensin-converting enzyme (zeige ACE Proteine)

Pig (Porcine) Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Interaktionspartner

  1. Combined administration of mesenchymal stem cells overexpressing IGF-1 (zeige IGF1 Proteine) and HGF enhances neovascularization but moderately improves cardiac regeneration in a porcine model.

  2. In an animal model of acute myocardial infarction relevant to human disease, intracoronary administration of IGF-1 (zeige IGF1 Proteine)/hepatocyte growth factor (HGF) is a practical and effective strategy to reduce pathological cardiac remodeling.

HGF Protein Überblick

Protein Überblick

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with HGF

  • hepatocyte growth factor (HGF)
  • hepatocyte growth factor (Hgf)
  • hepatocyte growth factor (hepapoietin A; scatter factor) (HGF)
  • hepatocyte growth factor (hepapoietin A; scatter factor) (Hgf)
  • hepatocyte growth factor-like (LOC100525120)
  • met proto-oncogene (Met)
  • AI838057 Protein
  • c-Met Protein
  • C230052L06Rik Protein
  • DFNB39 Protein
  • F-TCF Protein
  • HGF Protein
  • HGF/SF Protein
  • HGFB Protein
  • HGFR Protein
  • HPTA Protein
  • NK1 Protein
  • NK2 Protein
  • Par4 Protein
  • SF Protein
  • SF/HGF Protein

Bezeichner auf Proteinebene für HGF

hepatocyte growth factor , SF , hepatopoeitin-A , hepatopoietin-A , scatter factor , fibroblast-derived tumor cytotoxic factor , lung fibroblast-derived mitogen , hepapoietin A , HGF alpha-chain , hepatocyte growth factor /scatter factor , HGF receptor , HGF/SF receptor , SF receptor , hepatocyte growth factor receptor , met proto-oncogene tyrosine kinase , proto-oncogene c-Met , scatter factor receptor , tyrosine-protein kinase Met

GENE ID SPEZIES
708316 Macaca mulatta
15234 Mus musculus
24446 Rattus norvegicus
3082 Homo sapiens
100730730 Cavia porcellus
100316908 Oryctolagus cuniculus
403441 Canis lupus familiaris
282879 Bos taurus
395941 Gallus gallus
493705 Felis catus
443075 Ovis aries
100525120 Sus scrofa
17295 Mus musculus
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