anti-Human GRB2 Antikörper für Enzyme Immunoassay

Recommended GRB2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Growth Factor Receptor-Bound Protein 2 (GRB2) Antikörper
  • GRB2
  • grb2
  • AA408164
  • Ash
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • MST084
  • MSTP084
  • NCKAP2
  • wu:fb18e12
  • wu:fb34e06
  • zgc:73077
  • growth factor receptor-bound protein 2
  • Growth factor receptor-bound protein 2
  • growth factor receptor bound protein 2
  • growth factor receptor-bound protein 2b
  • GRB2
  • grb2
  • Grb2
  • LOC100342500
  • grb2b
Epitop
Middle Region
34
17
16
7
6
6
6
5
5
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
158
65
65
17
10
9
7
5
5
4
3
3
3
3
3
2
2
1
1
Wirt
Kaninchen
104
28
25
2
Klonalität
Polyklonal
Konjugat
Dieser GRB2 Antikörper ist unkonjugiert
8
4
3
3
3
3
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
141
69
55
30
13
7
5
2
2
2
2
1
Hersteller
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Bilder

Produktnummer ABIN358795
407,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5552700 EIA IHC (p) WB Goat C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN615406 EIA IHC (p) WB Goat C-Term Anmelden zum Anzeigen Polyclonal

anti-GRB2 Antikörper für Enzyme Immunoassay mit den meisten Publikationen

Ähnliche anti-GRB2 Antikörper

Applikation / Reaktivität Human
BioImaging (BI) 2 Antikörper
ELISA 69 Antikörper
Enzyme Immunoassay (EIA) 3 Antikörper
Immunochromatography (IC) 1 Antikörper
Immunocytochemistry (ICC) 5 Antikörper
Immunofluorescence (IF) 13 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 2 Antikörper
Immunohistochemistry (IHC) 55 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 31 Antikörper
Immunoprecipitation (IP) 7 Antikörper
Western Blotting (WB) 141 Antikörper

General

Antigen Growth Factor Receptor-Bound Protein 2 (GRB2) Antikörper
Epitop Middle Region
(34), (17), (16), (7), (6), (6), (6), (5), (5), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(158), (65), (65), (17), (10), (9), (7), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1)
Wirt Kaninchen
(104), (28), (25), (2)
Klonalität
Polyklonal
Konjugat Dieser GRB2 Antikörper ist unkonjugiert
(8), (4), (3), (3), (3), (3)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(141), (69), (55), (30), (13), (7), (5), (2), (2), (2), (2), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-GRB2 Antikörper

Target Details GRB2 Anwendungsinformationen Handhabung ProductDetails: References for anti-GRB2 antibody (ABIN358795) Bilder
Spezifität This antibody reacts to GRB2.
Reinigung Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human GRB2.
Isotyp Ig

Target Details GRB2

Produktdetails anti-GRB2 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-GRB2 antibody (ABIN358795) Bilder zurück nach oben
Antigen
Andere Bezeichnung GRB2 / ASH (GRB2 Antibody Abstract)
Hintergrund GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences.Synonyms: Growth factor receptor-bound protein 2
Gen-ID 2885, 9606
UniProt P62993
Forschungsgebiet Signaling
Pathways RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation

Anwendungsinformationen

Produktdetails anti-GRB2 Antikörper Target Details GRB2 Handhabung ProductDetails: References for anti-GRB2 antibody (ABIN358795) Bilder zurück nach oben
Applikationshinweise ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-GRB2 Antikörper Target Details GRB2 Anwendungsinformationen ProductDetails: References for anti-GRB2 antibody (ABIN358795) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-GRB2 antibody (ABIN358795)

Produktdetails anti-GRB2 Antikörper Target Details GRB2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Kondo, Hirayama, Sugito, Shono, Tanaka, Kitamura: "Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation." in: The Journal of biological chemistry, Vol. 283, Issue 3, pp. 1428-36, 2008

Morimatsu, Takagi, Ota, Iwamoto, Yanagida, Sako: "Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 46, pp. 18013-8, 2007

Martínez, García-Domínguez, Domingo, Oliva, Zarich, Sánchez, Gutiérrez-Eisman, Llopis, Rojas: "Sprouty2 binds Grb2 at two different proline-rich regions, and the mechanism of ERK inhibition is independent of this interaction." in: Cellular signalling, Vol. 19, Issue 11, pp. 2277-85, 2007

Bilder

Produktdetails anti-GRB2 Antikörper Target Details GRB2 Anwendungsinformationen Handhabung ProductDetails: References for anti-GRB2 antibody (ABIN358795) zurück nach oben
Bilder des Herstellers
 image for anti-GRB2 Antikörper (Growth Factor Receptor-Bound Protein 2) (Middle Region) (ABIN358795) anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (Middle Region) antibody
 image for anti-GRB2 Antikörper (Growth Factor Receptor-Bound Protein 2) (Middle Region) (ABIN358795) anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (Middle Region) antibody (Image 2)