anti-Rind (Kuh) GRB2 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended GRB2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Growth Factor Receptor-Bound Protein 2 (GRB2) Antikörper
  • GRB2
  • grb2
  • AA408164
  • Ash
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • MST084
  • MSTP084
  • NCKAP2
  • wu:fb18e12
  • wu:fb34e06
  • zgc:73077
  • growth factor receptor-bound protein 2
  • Growth factor receptor-bound protein 2
  • growth factor receptor bound protein 2
  • growth factor receptor-bound protein 2b
  • GRB2
  • grb2
  • Grb2
  • LOC100342500
  • grb2b
Epitop
AA 198-217, C-Term
33
17
16
6
6
6
6
5
5
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Human, Maus, Ratte (Rattus)
158
64
64
16
10
9
7
5
5
4
3
3
3
3
3
2
2
1
1
Wirt
Kaninchen
104
28
25
2
Klonalität
Polyklonal
Konjugat
Dieser GRB2 Antikörper ist unkonjugiert
8
4
3
3
3
3
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
141
69
55
30
13
7
5
3
2
2
2
1
Hersteller
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Bilder

Produktnummer ABIN615588
517,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
13.400779 ABIN364459 IHC (p) WB Mouse IgG1, kappa Anmelden zum Anzeigen
1 ABIN180592 IF IHC (p) Mouse IgG1 Anmelden zum Anzeigen 2GB04-same C1-4
1 ABIN5552700 EIA IHC (p) WB Goat C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN481756 IHC (p) ELISA WB Goat AA 206-217 Anmelden zum Anzeigen Polyclonal
1 ABIN2450618 IF IHC (p) Mouse IgG1, kappa AA 54-62 Anmelden zum Anzeigen 2GB04
1 ABIN384842 IF IHC (p) Mouse IgG1, kappa AA 54-62 Anmelden zum Anzeigen 2GB04
1 ABIN1735236 IHC (p) ELISA WB Goat C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN208556 IHC (fro) IF IHC (p) WB Mouse IgG1, kappa AA 54-62 Anmelden zum Anzeigen

Ähnliche anti-GRB2 Antikörper

Applikation / Reaktivität Human Maus Ratte (Rattus) Rind (Kuh)
Immunofluorescence (fixed cells) (IF/ICC) 2 Antikörper 1 Antikörper 1 Antikörper
Western Blotting (WB) 141 Antikörper 57 Antikörper 57 Antikörper 14 Antikörper
Immunoprecipitation (IP) 7 Antikörper 2 Antikörper 2 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 31 Antikörper 9 Antikörper 14 Antikörper 14 Antikörper
Immunohistochemistry (IHC) 55 Antikörper 14 Antikörper 13 Antikörper 1 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antikörper 1 Antikörper

General

Antigen Growth Factor Receptor-Bound Protein 2 (GRB2) Antikörper
Epitop AA 198-217, C-Term
(33), (17), (16), (6), (6), (6), (6), (5), (5), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Human, Maus, Ratte (Rattus)
(158), (64), (64), (16), (10), (9), (7), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1)
Wirt Kaninchen
(104), (28), (25), (2)
Klonalität
Polyklonal
Konjugat Dieser GRB2 Antikörper ist unkonjugiert
(8), (4), (3), (3), (3), (3)
Applikation Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(141), (69), (55), (30), (13), (7), (5), (3), (2), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-GRB2 Antikörper

Target Details GRB2 Anwendungsinformationen Handhabung Bilder
Spezifität The polyclonal antibody recognizes Grb2, a highly conserved approximately 26 kDa adaptor protein.
Reinigung Immunoaffinity Chromatography
Immunogen GRB2 antibody was raised against synthetic peptide corresponding to C-terminus of human Grb2 (amino acids 198-217). .Remarks: 100% identity between man, cow, rat and mouse

Target Details GRB2

Produktdetails anti-GRB2 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung GRB2 / ASH (GRB2 Antibody Abstract)
Hintergrund Growth factor receptor bound protein 2 (GRB2), also known as Ash protein, is a 24 kDa protein that contains a central Src homology (SH2) domain flanked by two SH3 domains. GRB2 is believed to be a regulatory subunit of signaling molecules whose activity is modulated by receptor binding. GRB2 associates with activated (tyrosine phosphorylated) EGFR and PDGFR via its SH2 domain as well as IRS1, SHC, and LNK through SH2 and SH3 domains. The SH3 domain binds to SOS, a guanine nucleotide exchange factor for Ras proteins. Endocytosis of activated EGFR requires the interaction of GRB2 with the GTP binding protein dynamin, a factor essential to the formation of endocytotic vesicle. It is ubiquitously expressed and several isoforms are produced by alternative splicing. On SDS PAGE, GRB2 has an apparent molecular weight of 28 kDa.Synonyms: Growth factor receptor-bound protein 2
Gen-ID 2885
NCBI Accession NP_002077
UniProt P62993
Forschungsgebiet Signaling
Pathways RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation

Anwendungsinformationen

Produktdetails anti-GRB2 Antikörper Target Details GRB2 Handhabung Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-GRB2 Antikörper Target Details GRB2 Anwendungsinformationen Bilder zurück nach oben
Buffer PBS containing 15 mM sodium azide and 0.2 % BSA
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Bilder

Produktdetails anti-GRB2 Antikörper Target Details GRB2 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-GRB2 Antikörper (Growth Factor Receptor-Bound Protein 2) (AA 198-217) (ABIN615588) IHC Image for AP23211PU-N Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-GRB2 Antikörper (Growth Factor Receptor-Bound Protein 2) (AA 198-217) (ABIN615588) IHC Image for AP23211PU-N Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-GRB2 Antikörper (Growth Factor Receptor-Bound Protein 2) (AA 198-217) (ABIN615588) IHC Image for AP23211PU-N Human Colon, Myenteric Plexus: Formalin-Fixed, Paraffin-Emb...