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Human FLT1 ELISA Kit für Sandwich ELISA - ABIN414833
Sun, Huang, Phillips, Luo, Zhu, Shi, Li: Growth differentiation factor 15 and coronary collateral formation. in Clinical cardiology 2010
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Human FLT1 ELISA Kit für Sandwich ELISA - ABIN411372
Du, Liu, Zhao, Wu, Gong, Zhou, Xu, Li, Shi, Qiao: Effects of maternal serum on permeability of glomerular endothelial cell membrane. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2011
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sFlt-1 overexpression in Padi4 (zeige PADI4 ELISA Kits)(-/-) mice resulted in dramatically lower inflammatory and thrombotic response, which was accompanied by significant reduction in pregnancy losses. Inhibition of NETosis may serve as a novel target in disorders of impaired placentation.
endothelial dysfunction due to high circulating sFLT1 may be the primary event leading to enhanced vasoconstrictor sensitivity that is characteristic of preeclampsia
Flt1 has a role in blood vessel anastomosis during angiogenesis
First-in-class selective PET tracers for imaging VEGFR-1 and VEGFR-2 (zeige KDR ELISA Kits) were constructed and successfully validated in an orthotopic murine tumor model.
these results suggest that VEGFR1 signaling plays a role in regulating the balance between macrophage phenotypes in streptozotocin -induced diabetic wounds, prevents impaired diabetic wound healing, and promotes angiogenesis/lymphangiogenesis.
These data therefore support a tightly controlled, paracrine signaling mechanism of VEGF-B (zeige VEGFB ELISA Kits) to VEGFR1.
Flt1/VEGF-A (zeige VEGFA ELISA Kits) signalling has stage-specific effects on vascular morphogenesis.
IL-35 treatment reduced collagen-induced arthritis via inhibiting vascular endothelial growth factor and its receptors
the VEGFR-1 tyrosine kinase (zeige TYRO3 ELISA Kits) signaling has an effect on angiogenesis.
data suggest that sFlt-1 may have a therapeutic effect on AS, resulting from suppression of VEGF signaling-mediated recruitment of circulating monocytes/macrophages
this study found no difference in VEGFR1 expression in infantile hemangiomas from the study and control group
MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA (zeige VEGFA ELISA Kits), VEGFR1, VEGFR2 (zeige KDR ELISA Kits), HGF (zeige HGF ELISA Kits) and MMP2 (zeige MMP2 ELISA Kits)
The SNPs rs9554322, rs9582036 and rs9943922 were correlated with age-related macular degeneration (AMD (zeige AMD1 ELISA Kits)). Gene variants in VEGFR1 were linked to a pronounced emerging risk for AMD (zeige AMD1 ELISA Kits) in a population in northern China.
Leptin (zeige LEP ELISA Kits)-induced transphosphorylation of vascular endothelial growth factor receptor (zeige RYK ELISA Kits) increases Notch (zeige NOTCH1 ELISA Kits) and stimulates endothelial cell angiogenic transformation
The study aimed to assess the usefulness of the determination of cytokines: IL-8 (zeige IL8 ELISA Kits), VEGF (zeige VEGFA ELISA Kits) and its soluble receptors: VEGF (zeige VEGFA ELISA Kits)-R1, VEGF (zeige VEGFA ELISA Kits)-R2 in patients with endometrial cancer. The concentrations of IL-8 (zeige IL8 ELISA Kits), VEGF (zeige VEGFA ELISA Kits), VEGFR1 and CA 125 (zeige MUC16 ELISA Kits) allowed to distinguish patients for the control group.
Gestational diabetes mellitus is associated with reduced expression of Flt-1 mRNA and protein.
Structure of the full-length VEGFR-1 extracellular domain in complex with VEGF-A (zeige VEGFA ELISA Kits) has been reported.
Results show that both FLT1 and PGF (zeige PGF ELISA Kits) are overexpressed in the circulating tumor cells (CTCs) of patients with breast cancer. Also, a functional interaction of sFlt1 and PGF (zeige PGF ELISA Kits) was found, suggesting that their overexpression in tumor cells inhibits CTCs entering the peripheral blood.
Results indicate that chymotrypsin-like serine protease (zeige F2 ELISA Kits) enhances soluble fms-like tyrosine kinase 1 production through protease-activated receptor-2 (zeige F2RL1 ELISA Kits) in trophoblast cells and thus plays an important additional role in preeclampsia pathogenesis.
variants near FLT1 may modulate preeclampsia susceptibility
There is a possibility that steatosis can be suppressed by the CC genotype in VEGFR1.
These results suggest that non-dominant follicles maintain a greater concentration of the mRNA expression of both membrane and soluble VEGF receptors; but follicular dominance is related to a reduction in the mRNA expression of sVEGFR1 and sVEGFR2.
VEGFR-1 negatively regulates primary bovine retinal pericytes survival, and its blockade protects the blood-brain barrier integrity.
gamma-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1
VEGFR1 mRNA expression was lower at estrus and at the early I and early II luteal stages than at the other stages, whereas VEGFR1 protein expression did not change significantly throughout the estrous cycle (P<0.05)
Alterations in the expression of VEGF-A (zeige VEGFA ELISA Kits) and bFGF (zeige FGF2 ELISA Kits) systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.
inhibition of VEGFR-1 results in decrease in number of capillary connections indicating VEGFR-1 ligands promote branching angiogenesis.
TGF-beta1 (zeige TGFB1 ELISA Kits) induction of VEGFR-1 in endothelial cells explains pericyte protection of vessels and the selective vulnerability of neonatal vessels to oxygen(VEGFR-1)
the activation of VEGFR-1 and VEGFR-2 (zeige KDR ELISA Kits) heterodimer (VEGFR-1/R-2) is essential for PGI(2 (zeige PTGIR ELISA Kits)) synthesis mediated by VEGF-A (zeige VEGFA ELISA Kits)(165) and VEGF-A (zeige VEGFA ELISA Kits)(121), which cannot be reproduced by the parallel activation of VEGFR-1 and VEGFR-2 (zeige KDR ELISA Kits) homodimers with corresponding agonists
PEDF (zeige SERPINF1 ELISA Kits) and VEGFR-1 have roles in the negative regulation of angiogenesis
we analyzed the expression and cellular distribution of Flt-1(VEGFR-1) and Flk-1 (KDR/VEGFR-2 (zeige KDR ELISA Kits))in newborn piglet brain
data shows that members of the VEGF (zeige VEGFA ELISA Kits)-VEGFR (zeige KDR ELISA Kits) system are temporally and spatially well localized for playing key roles during umbilical cord formation and its intensive growth observed after day 75 of pregnancy
The VEGFR1 was stably expressed during the whole lifespan of mesonephric glomeruli, and VEGFR1 is important for the maintenance of endothelial fenestrations.
increased placental expression of the VEGF receptor system is associated with increased placental vascular density observed with the advancement of gestation in the pig.
EGFR (zeige EGFR ELISA Kits), VEGFR (zeige KDR ELISA Kits) and FGFR (zeige FGFR2 ELISA Kits) are expressed in porcine oviduct and endometrium during the time of implantation [review]
VEGF ligand-receptor system may play an important role in the development and maintenance of the corpus luteum in pigs.
VEGF (zeige VEGFA ELISA Kits)/Flk-1 (zeige KDR ELISA Kits)/Flt-1 system is activated during myocardial ischemia reperfusion injury.
Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (zeige VEGFA ELISA Kits), pro-MMP-9 (zeige MMP9 ELISA Kits), MMP-2 (zeige MMP2 ELISA Kits), VEGFR-1, VEGFR-2 (zeige KDR ELISA Kits), and TIMP-1 (zeige TIMP1 ELISA Kits), which may contribute to the development of venous stenosis.
in experimental intervertebral disc degeneration, VEGF receptors were expressed in the damaged disc and paradiscal tissues
we determined that radial glia control this process via the Vegf (zeige VEGFA ELISA Kits) decoy receptor sFlt1: sflt1 mutants exhibit the venous over-sprouting observed in radial glia-ablated larvae, and sFlt1 overexpression rescues it. Genetic mosaic analyses show that sFlt1 function in trunk endothelial cells can limit their over-sprouting.
Flt1-tyrosine kinase (TK) activity contributed significantly in endothelial cells survival and vascular development during embryo angiogenesis in zebrafish by engaging PI3K/Akt (zeige AKT1 ELISA Kits) pathway.
Elevated Notch (zeige NOTCH1 ELISA Kits) signaling downstream of perturbed VEGF (zeige VEGFA ELISA Kits) signaling contributes to aberrant flt-1(-/-) blood vessel formation.
Data indicate that the increase in FLT1/sFLT1 protein levels upon miR-10 (zeige LILRB2 ELISA Kits) knockdown inhibited the angiogenic behavior of endothelial cells largely by antagonizing vascular endothelial growth factor receptor 2 (zeige KDR ELISA Kits) signaling.
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
fms-related tyrosine kinase 1
, vascular endothelial growth factor receptor 1
, embryonic receptor kinase 2
, tyrosine-protein kinase receptor FLT
, vascular endothelial growth factor receptor-1
, vascular permeability factor receptor
, fms-like tyrosine kinase 1
, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
, tyrosine-protein kinase FRT
, FMS-like tyrosine kinase 1
, Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
, vascular endothelial growth factor 1
, vascular endothelial growth factor/vascular permeability factor receptor
, ascular endothelial growth factor/vascular permeability factor receptor
, flt-1 type VEGF receptor
, receptor tyrosine kinase Flt1b
, soluble fms-like tyrosine kinase 1