anti-Human FGFR4 Antikörper für Immunocytochemistry

Recommended FGFR4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Fibroblast Growth Factor Receptor 4 (FGFR4) Antikörper
  • FGFR4
  • XFGFR-4
  • XFGFR-4a
  • cd334
  • fgfr-4
  • jtk2
  • tkf
  • xfgfr4
  • CD334
  • JTK2
  • TKF
  • Fgfr-4
  • etID309818.21
  • wu:fc13h10
  • zgc:111935
  • fgfr-4c
  • fgfr4
  • fibroblast growth factor receptor 4
  • FGFR4
  • fgfr4
  • Fgfr4
  • fgfr4-b
Reaktivität
Human
194
55
45
3
3
Wirt
Maus
125
67
17
1
Klonalität
Monoklonal
Konjugat
Dieser FGFR4 Antikörper ist unkonjugiert
8
7
7
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
151
95
54
38
34
29
13
9
7
5
4
3
2
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN969140
453,56 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
26.05542 ABIN4899673 FACS ICC IHC WB Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN2869400 ELISA ICC WB Mouse IgG1 Anmelden zum Anzeigen 7H1 2
1 ABIN4311563 ELISA ICC IF WB Mouse IgG1 Anmelden zum Anzeigen 7H1
1 ABIN1858881 ICC IHC IP WB Rabbit IgG AA 168-369 Anmelden zum Anzeigen Polyclonal
1 ABIN4311567 ICC IF IHC IHC (p) Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN4311568 ICC IF IHC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

anti-FGFR4 Antikörper für Immunocytochemistry mit den meisten Publikationen

Ähnliche anti-FGFR4 Antikörper

Applikation / Reaktivität Human
Cell Culture (CC) 1 Antikörper
ELISA 85 Antikörper
Enzyme Immunoassay (EIA) 5 Antikörper
Flow Cytometry (FACS) 38 Antikörper
Immunochromatography (IC) 1 Antikörper
Immunocytochemistry (ICC) 7 Antikörper
Immunofluorescence (IF) 29 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 2 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antikörper
Immunohistochemistry (IHC) 49 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 33 Antikörper
Immunoprecipitation (IP) 8 Antikörper
Proximity Ligation Assay (PLA) 1 Antikörper
Western Blotting (WB) 145 Antikörper

General

Antigen Fibroblast Growth Factor Receptor 4 (FGFR4) Antikörper
Reaktivität Human
(194), (55), (45), (3), (3)
Wirt Maus
(125), (67), (17), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser FGFR4 Antikörper ist unkonjugiert
(8), (7), (7), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(151), (95), (54), (38), (34), (29), (13), (9), (7), (5), (4), (3), (2), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-FGFR4 Antikörper

Target Details FGFR4 Anwendungsinformationen Handhabung ProductDetails: References for anti-FGFR4 antibody (ABIN969140) Bilder
Reinigung Ascites
Immunogen Purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line.
Klon 7H1
Isotyp IgG1

Target Details FGFR4

Produktdetails anti-FGFR4 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-FGFR4 antibody (ABIN969140) Bilder zurück nach oben
Antigen
Andere Bezeichnung FGFR4 (FGFR4 Antibody Abstract)
Hintergrund FGFR4: fibroblast growth factor receptor 4. Entrez Protein NP_002002. It is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.
Molekulargewicht 87.9 kDa
Gen-ID 2264
HGNC 2264
Forschungsgebiet Cancer, Growth Factors, Angiogenesis, Receptors
Pathways RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding

Anwendungsinformationen

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Handhabung ProductDetails: References for anti-FGFR4 antibody (ABIN969140) Bilder zurück nach oben
Applikationshinweise ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Anwendungsinformationen ProductDetails: References for anti-FGFR4 antibody (ABIN969140) Bilder zurück nach oben
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage

ProductDetails: References for anti-FGFR4 antibody (ABIN969140)

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Huang, Yang, Luo, Jin, Wang, McKeehan: "FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver." in: Diabetes, Vol. 56, Issue 10, pp. 2501-10, 2007

Streit, Mestel, Schmidt, Ullrich, Berking: "FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients." in: British journal of cancer, Vol. 94, Issue 12, pp. 1879-86, 2006

Bilder

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Anwendungsinformationen Handhabung ProductDetails: References for anti-FGFR4 antibody (ABIN969140) zurück nach oben
Bilder des Herstellers
Immunocytochemistry (ICC) image for anti-FGFR4 Antikörper (Fibroblast Growth Factor Receptor 4) (ABIN969140) Figure 1: Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfec...
Western Blotting (WB) image for anti-FGFR4 Antikörper (Fibroblast Growth Factor Receptor 4) (ABIN969140) Figure 2: Western blot analysis using FGFR4 mouse mAb against extracellular domain of...