anti-Human FGFR4 Antikörper für Flow Cytometry

Recommended FGFR4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Fibroblast Growth Factor Receptor 4 (FGFR4) Antikörper
  • FGFR4
  • XFGFR-4
  • XFGFR-4a
  • cd334
  • fgfr-4
  • jtk2
  • tkf
  • xfgfr4
  • CD334
  • JTK2
  • TKF
  • Fgfr-4
  • etID309818.21
  • wu:fc13h10
  • zgc:111935
  • fgfr-4c
  • fgfr4
  • fibroblast growth factor receptor 4
  • FGFR4
  • fgfr4
  • Fgfr4
  • fgfr4-b
Epitop
AA 24-55, N-Term
20
17
16
12
9
8
7
6
6
4
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human
207
56
45
3
3
Wirt
Kaninchen
126
69
27
1
Klonalität
Polyklonal
Konjugat
Dieser FGFR4 Antikörper ist unkonjugiert
8
8
7
4
4
4
4
4
4
4
3
3
3
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
155
97
55
47
34
28
13
9
9
6
4
3
2
2
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN391970
$ 324.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
14.05956 ABIN4896505 FACS Allophycocyanin Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
14.05956 ABIN4896506 FACS PE Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
14.05956 ABIN2661052 FACS IF Biotin Mouse IgG1 kappa Anmelden zum Anzeigen 4FR6D3 4
14.05956 ABIN2664587 FACS IHC Mouse IgG1 kappa Anmelden zum Anzeigen 4FR6D3 5
1 ABIN4899673 CyTOF FACS ICC IHC WB Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN4311573 FACS Alexa Fluor 647 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN4311572 FACS Alexa Fluor 700 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN4311571 FACS Alexa Fluor 488 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN4311574 FACS Alexa Fluor 750 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN4311577 FACS Alexa Fluor 405 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN4311576 FACS Alexa Fluor 350 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN4311575 FACS Alexa Fluor 594 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN5641302 FACS APC Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN5641305 FACS PE Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN671776 FACS PE Rabbit IgG AA 40-90 Anmelden zum Anzeigen Polyclonal
1 ABIN5646530 CyTOF FACS ICC IHC WB Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN5641310 FACS Alexa Fluor 405 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN5641304 FACS Alexa Fluor 700 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN5641308 FACS Alexa Fluor 594 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929
1 ABIN5641309 FACS Alexa Fluor 350 Rat IgG2a AA 22-369 Anmelden zum Anzeigen 240929

General

Antigen Fibroblast Growth Factor Receptor 4 (FGFR4) Antikörper
Epitop AA 24-55, N-Term
(20), (17), (16), (12), (9), (8), (7), (6), (6), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(207), (56), (45), (3), (3)
Wirt Kaninchen
(126), (69), (27), (1)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Dieser FGFR4 Antikörper ist unkonjugiert
(8), (8), (7), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(155), (97), (55), (47), (34), (28), (13), (9), (9), (6), (4), (3), (2), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-FGFR4 Antikörper

Target Details FGFR4 Anwendungsinformationen Handhabung Referenzen für anti-FGFR4 Antikörper (ABIN391970) Bilder
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This FGFR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-55 AA from the N-terminal region of human FGFR4.
Klon RB38171
Isotyp Ig

Target Details FGFR4

Produktdetails anti-FGFR4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-FGFR4 Antikörper (ABIN391970) Bilder zurück nach oben
Antigen
Andere Bezeichnung FGFR4 (FGFR4 Antibody Abstract)
Hintergrund FGFR4 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of the gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.

Synonyms: Fibroblast growth factor receptor 4
Pathways: Regulation of actin cytoskeleton, MAPK signaling pathway, Endocytosis
Molekulargewicht 87954 Da
Gen-ID 2264
UniProt P22455
Forschungsgebiet Cancer, Growth Factors, Angiogenesis, Receptors, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Cell Cycle
Pathways RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding

Anwendungsinformationen

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Handhabung Referenzen für anti-FGFR4 Antikörper (ABIN391970) Bilder zurück nach oben
Applikationshinweise Suggested dilutions:
IF = 1:200, WB = 1:1000, FACS = 1:10-50, IHC (p) = 1:50-100
Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Anwendungsinformationen Referenzen für anti-FGFR4 Antikörper (ABIN391970) Bilder zurück nach oben
Format Liquid
Konzentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung Avoid freeze-thaw cycles.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
Haltbarkeit 6 months

Referenzen für anti-FGFR4 Antikörper (ABIN391970)

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Jézéquel, Campion, Joalland, Millour, Dravet, Classe, Delecroix, Deporte, Fumoleau, Ricolleau: "G388R mutation of the FGFR4 gene is not relevant to breast cancer prognosis." in: British journal of cancer, Vol. 90, Issue 1, pp. 189-93, 2004

Bilder

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Anwendungsinformationen Handhabung Referenzen für anti-FGFR4 Antikörper (ABIN391970) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55), (N-Term) antibody (ABIN391970) Western blot analysis of anti-FGFR4 Pab (ABIN391970) in THP-1 cell lysate. FGRFR4 (Ar...
Immunohistochemistry (IHC) image for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55), (N-Term) antibody (ABIN391970) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Flow Cytometry (FACS) image for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55), (N-Term) antibody (ABIN391970) Flow cytometric analysis of WiDr cells using FGFR4 Antibody (N-term) (bottom histogra...