anti-Human FGFR4 Antikörper für Enzyme Immunoassay

Recommended FGFR4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Fibroblast Growth Factor Receptor 4 (FGFR4) Antikörper
  • FGFR4
  • XFGFR-4
  • XFGFR-4a
  • cd334
  • fgfr-4
  • jtk2
  • tkf
  • xfgfr4
  • CD334
  • JTK2
  • TKF
  • Fgfr-4
  • etID309818.21
  • wu:fc13h10
  • zgc:111935
  • fgfr-4c
  • fgfr4
  • fibroblast growth factor receptor 4
  • FGFR4
  • fgfr4
  • Fgfr4
  • fgfr4-b
Reaktivität
Human
207
56
45
3
3
Wirt
Kaninchen
126
69
27
1
Klonalität
Polyklonal
Konjugat
Dieser FGFR4 Antikörper ist unkonjugiert
8
8
7
4
4
4
4
4
4
4
3
3
3
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
155
97
55
48
35
29
13
9
9
5
4
3
2
2
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN359860
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5552242 EIA IHC (p) WB Rabbit Ig Fraction N-Term Anmelden zum Anzeigen Polyclonal
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1 ABIN614490 EIA IHC (fro) IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 4H2B10B2
1 ABIN1106283 EIA IF WB Mouse IgG1 Anmelden zum Anzeigen 7H1
1 ABIN2717942 EIA IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Fibroblast Growth Factor Receptor 4 (FGFR4) Antikörper
Reaktivität Human
(207), (56), (45), (3), (3)
Wirt Kaninchen
(126), (69), (27), (1)
Klonalität
Polyklonal
Konjugat Dieser FGFR4 Antikörper ist unkonjugiert
(8), (8), (7), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(155), (97), (55), (48), (35), (29), (13), (9), (9), (5), (4), (3), (2), (2), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-FGFR4 Antikörper

Target Details FGFR4 Anwendungsinformationen Handhabung Referenzen für anti-FGFR4 Antikörper (ABIN359860) Bilder
Spezifität This antibody reacts to FGFR4.
Reinigung Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with recombinant human FGFR4 protein.
Isotyp Ig

Target Details FGFR4

Produktdetails anti-FGFR4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-FGFR4 Antikörper (ABIN359860) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD334 / FGFR4 (FGFR4 Antibody Abstract)
Hintergrund FGFR4 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for family members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.Synonyms: FGFR-4, Fibroblast growth factor receptor 4, JTK2, TKF
Gen-ID 2264, 9606
UniProt P22455
Pathways RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding

Anwendungsinformationen

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Handhabung Referenzen für anti-FGFR4 Antikörper (ABIN359860) Bilder zurück nach oben
Applikationshinweise ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Anwendungsinformationen Referenzen für anti-FGFR4 Antikörper (ABIN359860) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-FGFR4 Antikörper (ABIN359860)

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Jézéquel, Campion, Joalland, Millour, Dravet, Classe, Delecroix, Deporte, Fumoleau, Ricolleau: "G388R mutation of the FGFR4 gene is not relevant to breast cancer prognosis." in: British journal of cancer, Vol. 90, Issue 1, pp. 189-93, 2004

Qian, Sano, Asa, Yamada, Horiguchi, Tashiro, Li, Hirokawa, Kovacs, Ezzat: "Cytoplasmic expression of fibroblast growth factor receptor-4 in human pituitary adenomas: relation to tumor type, size, proliferation, and invasiveness." in: The Journal of clinical endocrinology and metabolism, Vol. 89, Issue 4, pp. 1904-11, 2004

Yu, Asa, Weigel, Ezzat: "Pituitary tumor AP-2alpha recognizes a cryptic promoter in intron 4 of fibroblast growth factor receptor 4." in: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 19597-602, 2003

Becker, Nieters, Chang-Claude: "The fibroblast growth factor receptor gene Arg388 allele is not associated with early lymph node metastasis of breast cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 12, Issue 6, pp. 582-3, 2003

Takenaka, Yasuno, Kishimoto: "Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin." in: Archives of dermatological research, Vol. 294, Issue 7, pp. 331-8, 2002

Bilder

Produktdetails anti-FGFR4 Antikörper Target Details FGFR4 Anwendungsinformationen Handhabung Referenzen für anti-FGFR4 Antikörper (ABIN359860) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibody (ABIN359860) Western blot analysis of FGFR4 (arrow) using rabbit polyclonal FGFR4 Antibody.293 cel...