anti-Ratte (Rattus) ERBB3 Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended ERBB3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antikörper
  • ERBB3
  • ErbB-3
  • HER3
  • LCCS2
  • MDA-BF-1
  • c-erbB-3
  • c-erbB3
  • erbB3-S
  • p180-ErbB3
  • p45-sErbB3
  • p85-sErbB3
  • nuc-ErbB3
  • C76256
  • Erbb-3
  • Erbb3r
  • Her3
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
  • ERBB3
  • Erbb3
Epitop
AA 1305-1342, pTyr1328
40
40
38
27
21
19
15
15
15
15
14
14
13
12
10
10
10
9
8
7
7
5
5
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
535
198
172
14
7
6
6
4
3
3
3
2
2
2
2
1
1
Wirt
Kaninchen
302
230
28
4
Klonalität
Polyklonal
Konjugat
Dieser ERBB3 Antikörper ist unkonjugiert
14
13
12
11
11
11
8
8
8
8
7
6
6
5
5
5
5
5
5
4
3
3
3
3
3
3
3
3
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
313
194
149
128
106
84
66
57
11
11
10
8
8
7
4
4
3
2
2
2
1
1
1
Optionen
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Bilder

Produktnummer ABIN800628
$ 317.90
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN681358 FACS IF (p) IHC (p) WB Rabbit IgG AA 140-200 Anmelden zum Anzeigen Polyclonal
1 ABIN747113 IF (p) IHC (p) WB Rabbit IgG AA 1270-1310, pTyr1289 Anmelden zum Anzeigen Polyclonal
1 ABIN686767 IF (p) IHC (p) Rabbit IgG AA 670-720 Anmelden zum Anzeigen Polyclonal
1 ABIN2814281 FACS IF (p) Alexa Fluor 594 Rabbit IgG AA 140-200 Anmelden zum Anzeigen Polyclonal
1 ABIN2814285 IF (p) Alexa Fluor 594 Rabbit IgG AA 1305-1342, pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN800631 IF (p) Cy3 Rabbit IgG AA 1305-1342, pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN800633 IF (p) Cy5.5 Rabbit IgG AA 1305-1342, pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN800635 IF (p) FITC Rabbit IgG AA 1305-1342, pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN800634 IF (p) Cy7 Rabbit IgG AA 1305-1342, pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN681362 FACS IF (p) Cy5 Rabbit IgG AA 140-200 Anmelden zum Anzeigen Polyclonal
1 ABIN681361 FACS IF (p) Cy3 Rabbit IgG AA 140-200 Anmelden zum Anzeigen Polyclonal
1 ABIN681363 FACS IF (p) Cy5.5 Rabbit IgG AA 140-200 Anmelden zum Anzeigen Polyclonal
1 ABIN681365 FACS IF (p) FITC Rabbit IgG AA 140-200 Anmelden zum Anzeigen Polyclonal
1 ABIN681364 FACS IF (p) Cy7 Rabbit IgG AA 140-200 Anmelden zum Anzeigen Polyclonal
1 ABIN800632 IF (p) Cy5 Rabbit IgG AA 1305-1342, pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN878925 IF (p) Alexa Fluor 555 Rabbit IgG AA 1305-1342, pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN878923 IF (p) Alexa Fluor 350 Rabbit IgG AA 1305-1342, pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN878924 IF (p) Alexa Fluor 488 Rabbit IgG AA 1305-1342, pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN878926 IF (p) Alexa Fluor 647 Rabbit IgG AA 1305-1342, pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN900581 FACS IF (p) Alexa Fluor 647 Rabbit IgG AA 140-200 Anmelden zum Anzeigen Polyclonal

General

Antigen V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antikörper
Epitop AA 1305-1342, pTyr1328
(40), (40), (38), (27), (21), (19), (15), (15), (15), (15), (14), (14), (13), (12), (10), (10), (10), (9), (8), (7), (7), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(535), (198), (172), (14), (7), (6), (6), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Wirt Kaninchen
(302), (230), (28), (4)
Klonalität
Polyklonal
Konjugat Dieser ERBB3 Antikörper ist unkonjugiert
(14), (13), (12), (11), (11), (11), (8), (8), (8), (8), (7), (6), (6), (5), (5), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(313), (194), (149), (128), (106), (84), (66), (57), (11), (11), (10), (8), (8), (7), (4), (4), (3), (2), (2), (2), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-ERBB3 Antikörper

Target Details ERBB3 Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human HER3 around the phosphorylation site of Tyr1328 [PD(p-Y)WH]
Isotyp IgG

Target Details ERBB3

Produktdetails anti-ERBB3 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Her3 (ERBB3 Antibody Abstract)
Hintergrund

ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. Isoform 2 lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized. Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2), also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord.

Subcellular location: Cytoplasm

Synonyms: HER3, LCCS2, ErbB-3, c-erbB3, erbB3-S, MDA-BF-1, c-erbB-3, p180-ErbB3, p45-sErbB3, p85-sErbB3, Receptor tyrosine-protein kinase erbB-3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, ERBB3

Gen-ID 2065
UniProt P21860
Forschungsgebiet Cytokines, Receptors
Pathways RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung

Anwendungsinformationen

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Handhabung Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Bilder

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) (AA 1305-1342), (pTyr1328) antibody (ABIN800628) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti Phospho-HER3(...
Immunofluorescence (IF) image for anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) (AA 1305-1342), (pTyr1328) antibody (ABIN800628) Formalin-fixed and paraffin-embedded rat brain labeled with Anti-Phospho-HER3(Tyr1328...
Immunofluorescence (IF) image for anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) (AA 1305-1342), (pTyr1328) antibody (ABIN800628) Formalin-fixed and paraffin-embedded rat brain labeled with Anti-Phospho-HER3(Tyr1328...