anti-Maus ERBB3 Antikörper für Enzyme Immunoassay

Recommended ERBB3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antikörper
  • ERBB3
  • ErbB-3
  • HER3
  • LCCS2
  • MDA-BF-1
  • c-erbB-3
  • c-erbB3
  • erbB3-S
  • p180-ErbB3
  • p45-sErbB3
  • p85-sErbB3
  • nuc-ErbB3
  • C76256
  • Erbb-3
  • Erbb3r
  • Her3
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
  • ERBB3
  • Erbb3
Epitop
C-Term
40
39
27
22
21
19
15
15
15
15
15
14
13
12
12
10
10
9
8
7
7
5
5
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Hund, Human, Maus, Ratte (Rattus)
517
198
173
15
6
6
6
4
3
3
3
2
2
2
2
1
1
Wirt
Ziege
302
214
26
3
Klonalität
Polyklonal
Konjugat
Dieser ERBB3 Antikörper ist unkonjugiert
14
11
11
11
10
10
7
7
7
6
5
5
5
5
5
5
5
5
4
4
3
3
3
3
3
3
3
3
2
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
310
193
145
109
106
83
67
58
10
8
8
7
7
4
3
2
2
2
2
2
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN372474
517,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN359844 EIA IHC (p) WB Rabbit Ig N-Term Anmelden zum Anzeigen Polyclonal

Ähnliche anti-ERBB3 Antikörper

Applikation / Reaktivität Human Maus Ratte (Rattus) Hund
Immunofluorescence (fixed cells) (IF/ICC) 7 Antikörper 5 Antikörper 3 Antikörper
Cytometry by Time of Flight (CyTOF) 2 Antikörper
Western Blotting (WB) 299 Antikörper 116 Antikörper 101 Antikörper 5 Antikörper
Proximity Ligation Assay (PLA) 1 Antikörper
Neutralization (Neut) 8 Antikörper
Intracellular Flow Cytometry (ICFC) 2 Antikörper
Immunoprecipitation (IP) 52 Antikörper 22 Antikörper 21 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 105 Antikörper 28 Antikörper 25 Antikörper 2 Antikörper

General

Antigen V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antikörper
Epitop C-Term
(40), (39), (27), (22), (21), (19), (15), (15), (15), (15), (15), (14), (13), (12), (12), (10), (10), (9), (8), (7), (7), (5), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Hund, Human, Maus, Ratte (Rattus)
(517), (198), (173), (15), (6), (6), (6), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Wirt Ziege
(302), (214), (26), (3)
Klonalität
Polyklonal
Konjugat Dieser ERBB3 Antikörper ist unkonjugiert
(14), (11), (11), (11), (10), (10), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(310), (193), (145), (109), (106), (83), (67), (58), (10), (8), (8), (7), (7), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-ERBB3 Antikörper

Target Details ERBB3 Anwendungsinformationen Handhabung Bilder
Sequenz HSRLFPKANA QRT
Spezifität This antibody is expected to recognise isoform 1 (NP_001973.2) only.
Kreuzreaktivität (Details) Species reactivity (expected):Dog (Canine), Mouse and Rat.
Species reactivity (tested):Human.
Reinigung Immunoaffinity Chromatography.
Immunogen Synthetic peptide corresponding to C Terminus of ERBB3/HER3.
Isotyp IgG

Target Details ERBB3

Produktdetails anti-ERBB3 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung ERBB3 / HER3 (ERBB3 Antibody Abstract)
Hintergrund The ErbB3 gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized.Synonyms: ERBB-3, HER-3, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, c-erbB-3
Gen-ID 2065
NCBI Accession NP_001005915
UniProt P21860
Pathways RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung

Anwendungsinformationen

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Handhabung Bilder zurück nach oben
Applikationshinweise ELISA: 1/32000. Western blot: 0-1-0.3 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Anwendungsinformationen Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer TBS containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Bilder

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
 image for anti-ERBB3 Antikörper (V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian)) (C-Term) (ABIN372474) anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) (C-Term) antibody
 image for anti-ERBB3 Antikörper (V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian)) (C-Term) (ABIN372474) anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) (C-Term) antibody (Image 2)