anti-Human ERBB3 Antikörper für Immunocytochemistry

Recommended ERBB3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antikörper
  • ERBB3
  • ErbB-3
  • HER3
  • LCCS2
  • MDA-BF-1
  • c-erbB-3
  • c-erbB3
  • erbB3-S
  • p180-ErbB3
  • p45-sErbB3
  • p85-sErbB3
  • nuc-ErbB3
  • C76256
  • Erbb-3
  • Erbb3r
  • Her3
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
  • ERBB3
  • Erbb3
Epitop
AA 22-369
41
39
27
22
21
19
15
15
15
15
15
14
13
12
12
10
10
9
8
7
6
5
5
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
517
199
174
15
7
6
6
4
3
3
3
2
2
2
2
1
1
Wirt
Maus
302
213
27
3
Klonalität
Monoklonal
Konjugat
Dieser ERBB3 Antikörper ist unkonjugiert
14
11
11
11
10
10
7
7
7
6
5
5
5
5
5
5
5
5
4
4
3
3
3
3
3
3
3
3
2
Applikation
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
310
192
145
109
107
83
67
58
9
8
8
8
7
4
3
2
2
2
2
2
1
1
1
1
Optionen
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Bilder

Produktnummer ABIN969114
453,56 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN316283 ICC IF IHC (p) IHC WB Rabbit pTyr1328 Anmelden zum Anzeigen Polyclonal
1 ABIN251136 CyTOF ELISA FACS ICC IF IHC IP WB Mouse IgG1 Anmelden zum Anzeigen RTJ2 1
1 ABIN2869434 ELISA ICC WB Mouse IgG1 AA 22-369 Anmelden zum Anzeigen 2F9
1 ABIN4309300 ELISA ICC IF WB Mouse IgG1 Anmelden zum Anzeigen 2F9
1 ABIN211920 ICC IP IHC WB Mouse IgG2a, kappa AA 1295-1323 Anmelden zum Anzeigen
1 ABIN251137 CyTOF FACS ICC IF IHC IP Mouse IgG1 kappa Anmelden zum Anzeigen SGP1
1 ABIN2740676 ICC IF IHC (p) WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1867783 ICC IHC IP WB Rabbit IgG AA 709-966 Anmelden zum Anzeigen Polyclonal

anti-ERBB3 Antikörper für Immunocytochemistry mit den meisten Publikationen

Ähnliche anti-ERBB3 Antikörper

Applikation / Reaktivität Human
Blocking Antibody (Inhibition) 1 Antikörper
Cell Culture (CC) 1 Antikörper
Cytometry by Time of Flight (CyTOF) 2 Antikörper
Dot Blot (DB) 3 Antikörper
ELISA 180 Antikörper
ELISA (Capture) 2 Antikörper
ELISA (Detection) 1 Antikörper
Enzyme Immunoassay (EIA) 8 Antikörper
Flow Cytometry (FACS) 103 Antikörper
Functional Studies (Func) 1 Antikörper
Immunochromatography (IC) 4 Antikörper
Immunocytochemistry (ICC) 9 Antikörper
Immunofluorescence (IF) 81 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 7 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 67 Antikörper
Immunohistochemistry (IHC) 141 Antikörper
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antikörper

General

Antigen V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antikörper
Epitop AA 22-369
(41), (39), (27), (22), (21), (19), (15), (15), (15), (15), (15), (14), (13), (12), (12), (10), (10), (9), (8), (7), (6), (5), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(517), (199), (174), (15), (7), (6), (6), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Wirt Maus
(302), (213), (27), (3)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser ERBB3 Antikörper ist unkonjugiert
(14), (11), (11), (11), (10), (10), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Applikation Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(310), (192), (145), (109), (107), (83), (67), (58), (9), (8), (8), (8), (7), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-ERBB3 Antikörper

Target Details ERBB3 Anwendungsinformationen Handhabung ProductDetails: References for anti-ERBB3 antibody (ABIN969114) Bilder
Reinigung Ascites
Immunogen Purified recombinant extracellular fragment of human ERBB3 (aa22-369) fused with hIgGFc tag expressed in HEK293 cells.
Klon 2F9
Isotyp IgG1

Target Details ERBB3

Produktdetails anti-ERBB3 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-ERBB3 antibody (ABIN969114) Bilder zurück nach oben
Antigen
Andere Bezeichnung ERBB3 (ERBB3 Antibody Abstract)
Hintergrund ERBB3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian). It is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.
Molekulargewicht 148 kDa
Gen-ID 2065
HGNC 2065
Forschungsgebiet Receptors, Growth Factors, Cytokines
Pathways RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung

Anwendungsinformationen

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Handhabung ProductDetails: References for anti-ERBB3 antibody (ABIN969114) Bilder zurück nach oben
Applikationshinweise ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Anwendungsinformationen ProductDetails: References for anti-ERBB3 antibody (ABIN969114) Bilder zurück nach oben
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage

ProductDetails: References for anti-ERBB3 antibody (ABIN969114)

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Sassen, Rochon, Wild, Hartmann, Hofstaedter, Schwarz, Brockhoff: "Cytogenetic analysis of HER1/EGFR, HER2, HER3 and HER4 in 278 breast cancer patients." in: Breast cancer research : BCR, Vol. 10, Issue 1, pp. R2, 2008

Sakai, Yokote, Murakami-Murofushi, Tamura, Saijo, Nishio: "Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human lung cancer cells mediated by the HER3 signaling pathway." in: Cancer science, Vol. 98, Issue 9, pp. 1498-503, 2007

Bilder

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Anwendungsinformationen Handhabung ProductDetails: References for anti-ERBB3 antibody (ABIN969114) zurück nach oben
Bilder des Herstellers
Immunocytochemistry (ICC) image for anti-ERBB3 Antikörper (V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian)) (AA 22-369) (ABIN969114) Figure 1: Confocal immunofluorescence analysis of HEK293 cells trasfected with extrac...
Western Blotting (WB) image for anti-ERBB3 Antikörper (V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian)) (AA 22-369) (ABIN969114) Figure 2: Western blot analysis using ERBB3 mouse mAb against human ERBB3 (aa22-369) ...