anti-Human ERBB3 Antikörper für ELISA (Capture)

Recommended ERBB3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antikörper
  • ERBB3
  • ErbB-3
  • HER3
  • LCCS2
  • MDA-BF-1
  • c-erbB-3
  • c-erbB3
  • erbB3-S
  • p180-ErbB3
  • p45-sErbB3
  • p85-sErbB3
  • nuc-ErbB3
  • C76256
  • Erbb-3
  • Erbb3r
  • Her3
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
  • ERBB3
  • Erbb3
Epitop
AA 20-643
41
41
27
21
21
19
15
15
15
15
15
14
13
12
10
10
10
9
8
7
7
5
5
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
517
198
173
14
7
6
6
4
3
3
3
2
2
2
2
1
1
Wirt
Maus
303
212
27
3
Klonalität
Monoklonal
Konjugat
Dieser ERBB3 Antikörper ist unkonjugiert
14
11
11
11
10
10
7
7
7
6
5
5
5
5
5
5
5
5
4
4
3
3
3
3
3
3
3
3
2
Applikation
Cytometry by Time of Flight (CyTOF), ELISA (Capture), Flow Cytometry (FACS), Neutralization (Neut)
312
194
148
108
107
84
67
57
10
8
8
7
7
5
4
3
2
2
2
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN4899527
695,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN4899526 CyTOF ELISA (Capture) FACS Neut Mouse IgG1 AA 20-643 Anmelden zum Anzeigen 66223 5

General

Antigen V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antikörper
Epitop AA 20-643
(41), (41), (27), (21), (21), (19), (15), (15), (15), (15), (15), (14), (13), (12), (10), (10), (10), (9), (8), (7), (7), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(517), (198), (173), (14), (7), (6), (6), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Wirt Maus
(303), (212), (27), (3)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser ERBB3 Antikörper ist unkonjugiert
(14), (11), (11), (11), (10), (10), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Applikation Cytometry by Time of Flight (CyTOF), ELISA (Capture), Flow Cytometry (FACS), Neutralization (Neut)
(312), (194), (148), (108), (107), (84), (67), (57), (10), (8), (8), (7), (7), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-ERBB3 Antikörper

Target Details ERBB3 Anwendungsinformationen Handhabung ProductDetails: References for anti-ERBB3 antibody (ABIN4899527) Bilder
Spezifität Detects human ErbB3/Her3 in ELISAs. Does not cross-react with recombinant EGF R.
Reinigung Protein A or G purified from hybridoma culture supernatant
Sterilität 0.2 μm filtered
Endotoxin-Niveau <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen Mouse myeloma cell line NS0-derived recombinant human ErbB3/Her3, Ser20-Thr643, Accession # P21860
Klon 66223
Isotyp IgG1

Target Details ERBB3

Produktdetails anti-ERBB3 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-ERBB3 antibody (ABIN4899527) Bilder zurück nach oben
Antigen
Andere Bezeichnung ErbB3/Her3 (ERBB3 Antibody Abstract)
Hintergrund Alternative Names: c-erbB3, EC 2.7.10, EC 2.7.10.1, ErbB-3, erbB3-S, HER3, HER3c-erbB-3, LCCS2, lethal congenital contracture syndrome 2, MDA-BF-1, MGC88033, p180-ErbB3, p45-sErbB3, p85-sErbB3, Proto-oncogene-like protein c-ErbB-3, receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Gen-ID 2065
UniProt P21860
Forschungsgebiet Receptors, Growth Factors, Cytokines
Pathways RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung

Anwendungsinformationen

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Handhabung ProductDetails: References for anti-ERBB3 antibody (ABIN4899527) Bilder zurück nach oben
Applikationshinweise Flow Cytometry 2.5 μg/10^6 cells
Neutralization 0.0075-0.03 μg/mL
CyTOF-ready
ELISA Capture (Matched Antibody Pair) 2-8 μg/mL
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Anwendungsinformationen ProductDetails: References for anti-ERBB3 antibody (ABIN4899527) Bilder zurück nach oben
Rekonstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Konservierungsmittel Without preservative
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Haltbarkeit 12 months

ProductDetails: References for anti-ERBB3 antibody (ABIN4899527)

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Liu, Leng, Gunasekaran, Pentony, Shen, Howard, Stoops, Manchulenko, Razinkov, Liu, Fanslow, Hu, Sun, Hasegawa, Clark, Foltz, Yan: "A Novel Antibody Engineering Strategy for Making Monovalent Bispecific Heterodimeric IgG Antibodies by Electrostatic Steering Mechanism." in: The Journal of biological chemistry, 2015 Von den Autoren verwendete Methode: ELISA (Capture) (ELISA (Capture)) (Probematerial (Species): Human).

Khelwatty, Essapen, Seddon, Modjtahedi: "Growth response of human colorectal tumour cell lines to treatment with afatinib (BIBW2992), an irreversible erbB family blocker, and its association with expression of HER family members." in: International journal of oncology, Vol. 39, Issue 2, pp. 483-91, 2011 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Khan, Zhao, Ghosh, Ziman, Sweeney, Kung, Luciw: "Microbead arrays for the analysis of ErbB receptor tyrosine kinase activation and dimerization in breast cancer cells." in: Assay and drug development technologies, Vol. 8, Issue 1, pp. 27-36, 2010 Von den Autoren verwendete Methode: Immunoprecipitation (IP) (Probematerial (Species): Human).

Lin, Cheng, Lee, Ye, Tsai, Kim, Pasqualini, Arap, Navone, Tu, Hu, Yu-Lee, Logothetis: "A 45-kDa ErbB3 secreted by prostate cancer cells promotes bone formation." in: Oncogene, Vol. 27, Issue 39, pp. 5195-203, 2008 Von den Autoren verwendete Methode: ELISA (ELISA) (Probematerial (Species): Human).

Lin, Lee, Choueiri, Wen, Mathew, Ye, Do, Navone, Kim, Tu, Yu-Lee, Logothetis: "Soluble ErbB3 levels in bone marrow and plasma of men with prostate cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 12, pp. 3729-36, 2008 Von den Autoren verwendete Methode: ELISA (ELISA) (Probematerial (Species): Human).

Bilder

Produktdetails anti-ERBB3 Antikörper Target Details ERBB3 Anwendungsinformationen Handhabung ProductDetails: References for anti-ERBB3 antibody (ABIN4899527) zurück nach oben
Bilder des Herstellers
Neutralization (Neut) image for anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) (AA 20-643) antibody (ABIN4899527) Cell Proliferation Induced by NRG1-beta 1/HRG1-beta 1 and Neutralization by Human Erb...
Neutralization (Neut) image for anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) (AA 20-643) antibody (ABIN4899527) Cell Proliferation Induced by NRG1-beta 1/HRG1-beta 1 and Neutralization by Human Erb...