BDNF Proteine (BDNF)

Bezeichnung:
Brain-Derived Neurotrophic Factor Proteine (BDNF)
Auf www.antikoerper-online.de finden Sie aktuell 94 Brain-Derived Neurotrophic Factor (BDNF) Proteine von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BDNF Antikörper (348) und BDNF Kits (147) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 609 BDNF Produkte verfügbar.
Synonyme:
ANON2, bdnf, bdnf-A, BULN2
alle Proteine anzeigen Gen GeneID UniProt
BDNF 12064 P21237
BDNF 627 P23560
BDNF 24225 P23363

Weitere Synonyme anzeigen

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Am meisten referenzierte BDNF Proteine

  1. Human BDNF Protein expressed in Escherichia coli (E. coli) - ABIN1046638 : Jones, Reichardt: Molecular cloning of a human gene that is a member of the nerve growth factor family. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Zeige alle 2 Referenzen für 1046638

  2. Human BDNF Protein expressed in Escherichia coli (E. coli) - ABIN413062 : Kobayashi, Saito, Sato, Furusawa, Hosokawa, Tsutsumi, Asada, Kamada, Ohshima, Hisanaga: Phosphorylation of cyclin-dependent kinase 5 (Cdk5) at Tyr-15 is inhibited by Cdk5 activators and does not contribute to the activation of Cdk5. in The Journal of biological chemistry 2014 (PubMed)

  3. Human BDNF Protein expressed in Wheat germ - ABIN1346621 : Martin Bauknight, Chakrabarty, Hwang, Malone, Joshi, Bruce, Sander Connolly, Winfree, Cunningham, Martin, Haque: Convection enhanced drug delivery of BDNF through a microcannula in a rodent model to strengthen connectivity of a peripheral motor nerve bridge model to bypass spinal cord injury. in Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2012 (PubMed)

Weitere Proteine zu BDNF Interaktionspartnern

Zebrafish Brain-Derived Neurotrophic Factor (BDNF) Interaktionspartner

  1. These results suggest an involvement of the BDNF/TrkB (zeige NTRK2 Proteine) system in the regulation of food intake and energy balance in zebrafish, as in mammals

  2. BDNF-TrkB (zeige NTRK2 Proteine) influences the expression level of components of chemokine (zeige CCL1 Proteine) signaling including Cxcr4b, and the generation of progenitors of mechanoreceptors, at the level of expression of Atoh1a-Atp2b1a.

  3. Light regulates the expression of the BDNF/TrkB2 (zeige NTRK2 Proteine) system in the adult zebrafish retina.

  4. Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (zeige RACGAP1 Proteine) (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3 (zeige PARD3 Proteine)) protein.

  5. the results demonstrate that bdnf mediates non-cell-autonomous maintenance of position and thereby the identity of differentiated neurons

  6. The present results demonstrate that there is a parallel time-related decline in the expression of BDNF and TrkB (zeige NTRK2 Proteine) in zebrafish.

  7. The cloning and analysis of three additional zebrafish (Danio rerio) BDNF gene exons and two associated promoters, is reported. Among them are two exons that generate a novel tripartite mature transcript

  8. Loss of BDNF is a major cause of the developmental abnormalities seen with huntingtin (zeige HTT Proteine) knockdown in zebrafish.

Xenopus laevis Brain-Derived Neurotrophic Factor (BDNF) Interaktionspartner

  1. Together these results suggest an important role of BDNF in the maintenance and regeneration of the olfactory system.

  2. BDNF suppresses neuromuscular junction maturation through cAMP-PKA signaling pathway

  3. Findings demonstrate the neurotrophin, BDNF-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (zeige MAG Proteine) .

  4. These results indicate that brief sensory stimulation, by initiating nuclear transcription and de novo protein synthesis of BDNF, can facilitate the refinement of response properties in the developing visual system.

  5. In the Xenopus melanotrope, BDNF biosynthesis and processing occur along the secretory granule maturation axis, together with that of POMC (zeige POMC Proteine)-derived alphaMSH (zeige POMC Proteine), and that the light controls the biosynthesis and secretion of BDNF and of POMC (zeige POMC Proteine) end-products.

  6. BDNF released from the neural lobe of the pituitary gland acts as a neurohormone stimulating the secretory activity of the melanotrope cells in the intermediate pituitary lobe.

  7. BDNF influences synaptic connectivity in multiple ways, promoting not only the morphological maturation of axonal arbors but also their stabilization, but also their stabilization.

  8. BDNF, in addition to its neural and hormonal roles, can be released as a neurohormone from the neural pituitary lobe of X. laevis

  9. BDNF induces glial cell proliferation as well as axonal outgrowth and myelination in vivo.

  10. PACAP stimulates the expression of BDNF transcript IV.

Rhesus Monkey Brain-Derived Neurotrophic Factor (BDNF) Interaktionspartner

  1. Study showed that complex relationships exist between BDNF/TrkB (zeige NTRK2 Proteine) gene expression and interneuron marker gene expression that appear to be dependent on the presence of testosterone at adolescence

  2. In a monkey model, cortical BDNF and activity regulated cytoskeletal-associated protein ARC (zeige Arc Proteine) expressions are strongly correlated with spontaneous physical activity.

  3. A SNP is present in rhesus macaques and is able to affect BDNF peripheral levels, thus making this primate model a fundamental tool to study gene by environment interactions involving the BDNF gene.

  4. In monkey the decline of the BDNF protein level started earlier in the sensory and motor neocortical areas than in the association neocortical areas.

Mouse (Murine) Brain-Derived Neurotrophic Factor (BDNF) Interaktionspartner

  1. study examined the effect of molar loss and powder diet on memory ability and the expression of BDNF mRNA in the hippocampus of adult mice; results suggest the effect of molar loss and powder diet on memory function and BDNF mRNA levels were different, molar loss may have a greater long-term effect on memory ability than powder diet does

  2. This study demonstrated that BDNF is required for nerve regeneration following gustatory nerve section.

  3. Activity-dependent and brain-derived neurotrophic factor-dependent neuroplasticity within the orbitofrontal cortex coordinate outcome-based decision making through interactions with the amygdala. These interactions break reward-seeking habits, a putative factor in multiple psychopathologies.

  4. findings show that BDNF-TrkB (zeige NTRK2 Proteine) signaling, rather than Dopamine signaling, in the Ventral Tegmental Area -Nuc (zeige SREBF2 Proteine). Accumbens circuit is crucial for facilitating depressive-like depressive-like outcomes after Chronic Social Defeat Stress and they establish BDNF-TrkB (zeige NTRK2 Proteine) signaling as a pathologic mechanism during periods of chronic stress.

  5. Study showed that BDNF promotes regeneration induced by spared nerve injury, involving the GAP-43 (zeige GAP43 Proteine) and NFH (zeige NEFH Proteine) modulation under the stabilizing activity of HuD (zeige ELAVL4 Proteine).

  6. Activation of S1R, necessary for its effect on the BDNF pathway, represents a core component of the mode of action of pridopidine. Since the newly identified pathways are downregulated in neurodegenerative diseases, including Huntington Disease (HD (zeige HTT Proteine)) , these findings suggest that pridopidine may exert neuroprotective effects beyond its role in alleviating some symptoms of HD.

  7. Brain-derived neurotrophic factor Val66Met polymorphism exerts an increase in glutamatergic transmission but impairs synaptic plasticity in the dorsal striatum, which might play a role in its effect on neuropsychiatric symptoms.

  8. Inhibition of BDNF-AS protected retinal ganglion cells against ischemia by increasing the levels of BDNF.

  9. Human microvascular endothelial cells promote the development of dorsal root ganglion neurons via BDNF pathway in a co-culture system.

  10. Results imply that oleanolic acid ameliorates scopolamine-induced memory impairment by modulating the brain-derived neurotrophic factor -ERK1/2-cAMP response element-binding protein pathway through tropomyosin receptor kinase (zeige NTRK1 Proteine) B activation in mice, suggesting that oleanolic acid would be a potential therapeutic agent for the treatment of cognitive deficits.

Human Brain-Derived Neurotrophic Factor (BDNF) Interaktionspartner

  1. Serum BDNF level was found lower in the tinnitus patients than controls, and it appeared that there is no correlation between BDNF gene polymorphism and tinnitus.

  2. The conclude of this study that intermittent/continuous theta-burst stimulation failed to induce LTP (zeige SCP2 Proteine)-/LTD-like plasticity in patients with Gilles de la Tourette syndrome, and this was not affected by BDNF.

  3. Women with stable coronary artery disease have increased platelet BDNF levels when compared to men with stable coronary artery disease regardless of their level of depression. Sex specific differences in BDNF could possibly indicate differences in factors linking platelet activation and depression in men and women.

  4. ASM (zeige SMPD1 Proteine) as an inflammation-sensitive source of BDNF within human airways.

  5. Serum BDNF, VEGF (zeige VEGFA Proteine), and IGF-1 (zeige IGF1 Proteine) levels were significantly higher in the Taekwondo (TKD) training group after the 16-week intervention. The training may have been effective in increasing children's cognitive function by inducing an increase in the levels of neuroplasticity-related growth factors.

  6. This is the first study to suggest that known and newly described polymorphisms in COMT (zeige COMT Proteine), BDNF, and DTNBP1 (zeige DTNBP1 Proteine), genes associated with executive and memory functions in healthy individuals and other clinical populations may modulate cognitive outcome in patients with brain tumors

  7. Results show no significant association between the BDNF gene Val66Met polymorphism and BDNF serum levels in pediatric bipolar disorder but its serum levels were significantly different between bipolar disorder (BD) and attention-deficit/hyperactivity disorder (ADHD) and ADHD, suggesting different biological underpinnings between these disorders.

  8. The Val/Val genotype was associated with greater severity of CAD and incidence of CVD-related clinical events in a patient sample. If these findings are confirmed in further research, intervention studies in clinical groups with the Val/Val genotype could be undertaken to prevent disease and improve prognosis.

  9. Serum levels of BDNF are strongly induced during acute exercise even in patients with progressive multiple sclerosis.

  10. BDNF and NGF serum levels are reduced in the early and moderate glaucoma stages, suggesting the possibility that both factors could be further investigated as potential circulating biomarkers for the early detection of glaucoma.

Cow (Bovine) Brain-Derived Neurotrophic Factor (BDNF) Interaktionspartner

  1. These observations provided evidence that brain-derived naeurotrophic factor(BDNF) and its receptor (BDNF receptor) secreted by bovine sperm was important in regulation of insulin (zeige INS Proteine) and leptin (zeige LEP Proteine).

  2. Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic pathway involving BDNF.

Pig (Porcine) Brain-Derived Neurotrophic Factor (BDNF) Interaktionspartner

  1. Lf upregulated several canonical signaling pathways associated with neurodevelopment and cognition and influenced ~10 genes involved in the brain-derived neurotrophin factor (BDNF) signaling pathway.

  2. Taken together, these data indicate that recurrent tethering stress in sows over 4.5 years results in a loss of neurotrophic support by BDNF, mediated by an overactive neuroendocrine system.

  3. FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (zeige MMP9 Proteine) and MMP-2 (zeige MMP2 Proteine), caspase-3 (zeige CASP3 Proteine) and BDNF

BDNF Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.

Alternative names and synonyms associated with BDNF

  • brain-derived neurotrophic factor (bdnf)
  • brain-derived neurotrophic factor (bdnf-A)
  • brain-derived neurotrophic factor (BDNF)
  • brain derived neurotrophic factor (Bdnf)
  • brain-derived neurotrophic factor (Bdnf)
  • brain-derived neurotrophic factor (bdnf-b)
  • brain-derived neurotrophic factor-like (LOC100356949)
  • ANON2 Protein
  • bdnf Protein
  • bdnf-A Protein
  • BULN2 Protein

Bezeichner auf Proteinebene für BDNF

brain-derived neurotrophic factor , brain derived neurotrophic factor , anorexia BDNF , abrineurin , neurotrophin , brain derived neurothrophic factor , neurotrophic factor , pre-pro-brain-derived

GENE ID SPEZIES
58118 Danio rerio
378585 Xenopus laevis
554233 Monodelphis domestica
701245 Macaca mulatta
751584 Taeniopygia guttata
100037853 Xenopus (Silurana) tropicalis
100135487 Cavia porcellus
100313500 Oncorhynchus mykiss
12064 Mus musculus
627 Homo sapiens
24225 Rattus norvegicus
617701 Bos taurus
396186 Gallus gallus
100730257 Cavia porcellus
397495 Sus scrofa
100009689 Equus caballus
403461 Canis lupus familiaris
493690 Felis catus
101117275 Ovis aries
100048914 Xenopus laevis
100500698 Ailuropoda melanoleuca
503511 Pan troglodytes
100356949 Oryctolagus cuniculus
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