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data suggest that the anti-Sm D response arises as a consequence of antigenic cross-reactivity by anti-EBNA-1 antibodies, supporting a possible association between EBV infection and SLE
SmD1 83-119 peptide may play a dominant role in the activation of helper and regulatory T cells that influence autoantibody generation and murine lupus.
Data show that the elevation of cerebrospinal fluid anti-Sm antibodies through transudation from systemic circulation due to damaged blood-brain barrier (BBB (zeige ALMS1 ELISA Kits)) plays a critical role in the pathogenesis of acute confusional state (ACS (zeige PLA2G15 ELISA Kits)).
The interaction of SMN (zeige STMN1 ELISA Kits) with the spliceosomal SmD1 (also known as SNRPD1), severely decreases SMN (zeige STMN1 ELISA Kits)-coilin (zeige COIL ELISA Kits) interaction and prevents Cajal body assembly.
Overexpression of SNRPD1 is associated with highly aggressive breast cancers.
This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA.
, small nuclear ribonucleoprotein Sm D1
, snRNP core protein D1
, Sm-D autoantigen
, small nuclear ribonucleoprotein D1 polypeptide 16kDa pseudogene
, small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
, small nuclear ribonucleoprotein D1 polypeptide 16kDa