anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) Antikörper

Bezeichnung:
anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 Antikörper (SART3)
Auf www.antikoerper-online.de finden Sie aktuell 42 Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) Antikörper von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Squamous Cell Carcinoma Antigen Recognized By T Cells 3 Proteine (12) und Squamous Cell Carcinoma Antigen Recognized By T Cells 3 Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 63 Squamous Cell Carcinoma Antigen Recognized By T Cells 3 Produkte verfügbar.
Synonyme:
AU045857, DKFZp469J2418, DSAP1, mKIAA0156, P100, p110, p110(nrb), RP11-13G14, SART3, si:ch211-191d15.4, TIP110, wu:fc51h03
Alle Antikörper anzeigen Gen GeneID UniProt
SART3 9733 Q15020
SART3 53890 Q9JLI8
SART3 304582  

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Am meisten referenzierte anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 Antikörper

  1. Dog (Canine) Polyclonal SART3 Primary Antibody für IHC, WB - ABIN2780944 : Liu, Li, Kim, Pace, He: HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110. in The Journal of biological chemistry 2002 (PubMed)
    Zeige alle 2 Referenzen für 2780944

  2. Cow (Bovine) Polyclonal SART3 Primary Antibody für WB - ABIN2775728 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

  3. Human Polyclonal SART3 Primary Antibody für ELISA, WB - ABIN184889 : Bell, Schreiner, Damianov, Reddy, Bindereif: p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor. in The EMBO journal 2002 (PubMed)

Weitere Antikörper gegen Squamous Cell Carcinoma Antigen Recognized By T Cells 3 Interaktionspartner

Human Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) Interaktionspartner

  1. We show that PRP31 (zeige PRPF31 Antikörper), a component of U4 snRNP (zeige LSM2 Antikörper), is modified with K63-linked ubiquitin chains by the PRP19 (zeige PRPF19 Antikörper) complex and deubiquitinated by USP15 (zeige USP15 Antikörper) and its substrate targeting factor SART3. USP15SART3 makes a complex with USP4 (zeige USP4 Antikörper) and this ternary complex serves as a platform to deubiquitinate PRP31 (zeige PRPF31 Antikörper) and PRP3 (zeige CLCA4 Antikörper)

  2. The complex structure of SART3 nuclear localization signal (NLS (zeige ALDH1A2 Antikörper)) and importin-alpha reveals bipartite binding, and removal of SART3 NLS (zeige ALDH1A2 Antikörper) prevents the entry of USP4 (zeige USP4 Antikörper) (and USP15 (zeige USP15 Antikörper)) into the nucleus and abrogates the subsequent deubiquitinase activity of USP4 (zeige USP4 Antikörper).

  3. crystal structures of SART3 in the apo (zeige C9orf3 Antikörper)-form and in complex with the DUSP (zeige DUSP5 Antikörper)-UBL domain of USP15 (zeige USP15 Antikörper) at 2.0 and 3.0 A, respectively. Structural analysis reveals SART3 contains 12 half-a-tetratricopeptide (HAT (zeige MGEA5 Antikörper)) repeats, organized into two subdomains, HAT (zeige MGEA5 Antikörper)-N and HAT (zeige MGEA5 Antikörper)-C. SART3 dimerizes through the concave surface of HAT (zeige MGEA5 Antikörper)-C, whereas the HAT (zeige MGEA5 Antikörper)-C convex surface binds USP15 (zeige USP15 Antikörper) in a novel bipartite mode.

  4. miR (zeige MLXIP Antikörper)-124 regulates Tip110 expression and differentiation of human cord blood CD34 (zeige CD34 Antikörper)(+) cells

  5. Hypoxia led to Tip110 protein degradation through the ubiquitin-proteasome system. Under hypoxia, Tip110 stabilized p53 (zeige TP53 Antikörper), which in return destabilized Tip110.

  6. SART3 recruits ubH2B, which may be evicted from DNA during transcription, for deubiquitination by Usp15 (zeige USP15 Antikörper)

  7. YB-1 (zeige YBX1 Antikörper) potentiates the Tip110/Tat (zeige TAT Antikörper)-mediated transactivation of the HIV-1 LTR promoter.

  8. findings show C-MYC (zeige MYC Antikörper) upregulates transcription of TIP110 through interaction with the TIP110 E-box in the TIP110 promoter, ensuring high-level Tip110 expression in proliferating embryonic stem cells (hESCs); further show TIP110 regulates OCT4 (zeige POU5F1 Antikörper) alternative splicing in hESCs

  9. TIP110 is also expressed in human embryonic stem cells (hESCs) and expression was decreased with differentiation of these ESCs (zeige NR2E3 Antikörper).

  10. Results suggest that U4 and U6 small nuclear ribonucleoproteins (snRNPs) accumulate in Cajal bodies for the purpose of assembly into U4/U6 snRNPs by SART3/p110.

Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.

Alternative names and synonyms associated with Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3)

  • squamous cell carcinoma antigen recognized by T cells 3 (SART3) Antikörper
  • squamous cell carcinoma antigen recognized by T cells 3 (sart3) Antikörper
  • squamous cell carcinoma antigen recognized by T cells 3 (LOC100354995) Antikörper
  • squamous cell carcinoma antigen recognised by T cells 3 (sart3) Antikörper
  • squamous cell carcinoma antigen recognized by T cells 3 (Sart3) Antikörper
  • squamous cell carcinoma antigen recognized by T-cells 3 (Sart3) Antikörper
  • AU045857 Antikörper
  • DKFZp469J2418 Antikörper
  • DSAP1 Antikörper
  • mKIAA0156 Antikörper
  • P100 Antikörper
  • p110 Antikörper
  • p110(nrb) Antikörper
  • RP11-13G14 Antikörper
  • SART3 Antikörper
  • si:ch211-191d15.4 Antikörper
  • TIP110 Antikörper
  • wu:fc51h03 Antikörper

Bezeichner auf Proteinebene für SART3

squamous cell carcinoma antigen recognized by T cells 3 , Squamous cell carcinoma antigen recognized by T-cells 3 , squamous cell carcinoma antigen recognized by T-cells 3-like , earl grey , egy , p110 , squamous cell carcinoma antigen recognized by T-cells 3 , SART-3 , hSART-3 , tat-interacting protein of 110 kDa , mSART-3 , tumor-rejection antigen SART3

GENE ID SPEZIES
416890 Gallus gallus
467123 Pan troglodytes
549486 Xenopus (Silurana) tropicalis
705552 Macaca mulatta
100025301 Monodelphis domestica
100066913 Equus caballus
100076409 Ornithorhynchus anatinus
100137683 Xenopus laevis
100171719 Pongo abelii
100354995 Oryctolagus cuniculus
100410722 Callithrix jacchus
100557456 Anolis carolinensis
100585960 Nomascus leucogenys
558581 Danio rerio
9733 Homo sapiens
486319 Canis lupus familiaris
505922 Bos taurus
53890 Mus musculus
100152586 Sus scrofa
304582 Rattus norvegicus
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