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Data show that Cbp80 knockdown not only led to the upregulation of transposons, but also to delocalization of Piwi (zeige PIWIL1 ELISA Kits), Aub and Ago3 (zeige EIF2C3 ELISA Kits), key factors in the piRNA biosynthesis pathway.
Sgf11 interacts with the cap-binding protein 80 (Cbp80) component of the cap-binding complex, and that Cbp80 knockdown interferes with Sgf11 recruitment on the hsp70 promoter.
Study proposes the existence of an alternative cap-binding complex involving NCBP1 and NCBP3 that plays a key role in mRNA biogenesis.
down-regulation of CTIF (zeige KIAA0427 ELISA Kits) using a small interfering RNA causes a redistribution of CBP80 from polysome fractions to subpolysome fractions, without significant consequence to eIF4E (zeige EIF4E ELISA Kits) distribution
Cellular processes by which CBP80-CBP20 (zeige NCBP2 ELISA Kits) -bound messenger ribonucleoproteins (mRNPs) are remodeled to eIF4E (zeige EIF4E ELISA Kits)-bound mRNPs, are overviewed.
Viral mRNA associates with the influenza virus A NS1 (zeige PTPN11 ELISA Kits) and the cellular NCBP1 of the nuclear cap-binding complex.
UPF1 (zeige UPF1 ELISA Kits) binds PTC (zeige F9 ELISA Kits)-containing mRNA more efficiently than the corresponding PTC (zeige F9 ELISA Kits)-free mRNA in a way that is promoted by the UPF1 (zeige UPF1 ELISA Kits)-CBP80 interaction.
crystal structure at 2.1 A resolution of CBP20 (zeige NCBP2 ELISA Kits) and CBP80 bound to an m(7)GpppG cap analogue
Structural basis of m7GpppG binding to the nuclear cap-binding protein (zeige EIF4E ELISA Kits) complex.
The organization of the CBP80-CBP20 (zeige NCBP2 ELISA Kits) complex suggests how the activity of eIF4G (zeige EIF4G1 ELISA Kits) in translation initiation could be regulated through a dynamic network of overlapping intra- and intermolecular interactions.
During nonsense-mediated mRNA decay, CBP80 interacts with Upf1 (zeige UPF1 ELISA Kits) and promotes the interaction of Upf1 (zeige UPF1 ELISA Kits) with Upf2 but not with Stau1 (zeige STAU1 ELISA Kits).
Association of CBC with PARN (zeige PARN ELISA Kits) might have importance in the regulated recruitment of PARN (zeige PARN ELISA Kits) to the nonsense-mediated decay pathway during the pioneer round of translation.
the identification of new genes involved in ABA-dependent abiotic stresses using Arabidopsis suppressor mutants of abh1 (zeige ALKBH ELISA Kits) hypersensitivity to ABA during seed germination.
Data suggest that CBP20 (zeige NCBP2 ELISA Kits) and CBP80 (ABH1) have synergistic roles during the salt stress response.
SERRATE, CAP BINDING PROTEIN20 (CBP20 (zeige NCBP2 ELISA Kits)), and CBP80 are regulators of lincRNA expression and biogenesis. RT-PCR experiments confirmed these three proteins are also needed for splicing of a small group of intron-containing lincRNAs.
This intron suppression of transgene silencing requires efficient intron splicing and is dependent on ABH1 (zeige ALKBH ELISA Kits).
ABH1 (CBP80) encodes a large subunit of CBC (CAP BINDING COMPLEX) and the abh1 (zeige ALKBH ELISA Kits) mutant is drought-tolerant and hypersensitive to ABA during seed germination.
The cbp80(abh1) and cbp20 (zeige NCBP2 ELISA Kits)/80 mutants had many more changes in alternative splicing in common than did cbp20 (zeige NCBP2 ELISA Kits) and cbp20 (zeige NCBP2 ELISA Kits)/80 suggesting that CBP80 plays a more significant role in alternative splicing than CBP20 (zeige NCBP2 ELISA Kits).
Abh1 (zeige ALKBH ELISA Kits) lesion affects several developmental processes, perhaps because the processing of certain mRNAs.
CBP20 and CBP80 function in miRNA biogenesis by binding to pri-miRNA transcripts, and are stabilized by ABA by a post-translational mechanism.
AtCBP80 is required for the stability of AtCBP20 (zeige NCBP2 ELISA Kits) in the plant cell.
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.
, Cap-binding protein 80
, nuclear cap-binding protein subunit 1
, NCBP 80 kDa subunit
, 80 kDa nuclear cap-binding protein
, nuclear cap-binding protein subunit 1-B
, nuclear cap binding protein subunit 1, 80kDa
, nuclear cap-binding protein subunit 1-like
, nuclear cap-binding protein subunit 1-A