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Human Polyclonal ATG7 Primary Antibody für IF, IHC (p) - ABIN388522
Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005
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Human Polyclonal ATG7 Primary Antibody für ICC, IF - ABIN269462
Park, Lee, Kim, Lee, Lee, Kim, Jang, Choi, Kwon, Kim: A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells. in Cancer research 2007
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Human Polyclonal ATG7 Primary Antibody für IHC (p), WB - ABIN388521
Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005
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Human Polyclonal ATG7 Primary Antibody für EIA, WB - ABIN118061
Aoki, Kobayashi, Tanida, Hatano, Komori, Matsumoto, Nishioka, Uemura: [A difficult case of esophageal and gastric double cancer with pleural and pericardial effusion following chemo-radiotherapy (CRT)] in Gan to kagaku ryoho. Cancer & chemotherapy 2008
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Human Polyclonal ATG7 Primary Antibody für IHC (p), WB - ABIN4282130
Lee, Chen, Su, Chueh: Sirtuin 1 (SIRT1) Deacetylase Activity and NAD⁺/NADH Ratio Are Imperative for Capsaicin-Mediated Programmed Cell Death. in Journal of agricultural and food chemistry 2015
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Human Polyclonal ATG7 Primary Antibody für IHC (p), WB - ABIN388520
Greenberg: Degrade or die: a dual function for autophagy in the plant immune response. in Developmental cell 2005
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Human Polyclonal ATG7 Primary Antibody für IF, IHC (p) - ABIN388523
Levine: Eating oneself and uninvited guests: autophagy-related pathways in cellular defense. in Cell 2005
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Human Monoclonal ATG7 Primary Antibody für WB - ABIN387793
Metzger, Saukko, Van Che, Tong, Puder, Riess, Nguyen: Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7. in Human genetics 2010
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SNP rs11706903 in ATG7 was not associated with systemic lupus erythematosus I Chinese Han population.
low serum ATG7 is associated with ulcerative colitis
The U2AF35 (zeige U2AF1 Antikörper)(S34F) mutation alters interaction with CFIm59 (zeige CPSF7 Antikörper), leading to increased use of a distal cleavage and polyadenylation site in the ATG7 pre-mRNA, decreasing levels of ATG7 protein and defective autophagy, ultimately leading to transformation.
the inhibition of Atg7 appears to be a valid strategy to enhance chemosensitivity, and it could indeed improve outcomes in acute myeloid leukemia (zeige BCL11A Antikörper) therapy.
Our data demonstrate that HOTAIR promotes the activation of autophagy in HCC (zeige FAM126A Antikörper) cells by upregulating the expression of the autophagy-related genes ATG3 (zeige ATG3 Antikörper) and ATG7.
Autophagy-related gene ATG7 was validated as a target of miR-17 seed family.
the upregulation of autophagy-related gene (Atg) and wingless/int1 (zeige WNT1 Antikörper) (Wnt (zeige WNT2 Antikörper)) signaling during BMP-2 (zeige BMP2 Antikörper)-mediated human osteoblastic differentiation, was examined.
Aldo was revealed to induce autophagy, as indicated by the increased conversion from microtubuleassociated protein 1A/1Blight chain 3 (LC3)I to LC3II, the increased expression levels of autophagyrelated gene 7 (Atg7) and the increased degradation of p62, which was accompanied by MC proliferation
PVT1 overexpression increased the expression of Atg7 and Beclin1 (zeige BECN1 Antikörper) by targeting miR (zeige MLXIP Antikörper)-186, which induced protective autophagy, thus promoting glioma vascular endothelial cell proliferation, migration, and angiogenesis. Therefore, PVT1 and miR (zeige MLXIP Antikörper)-186 can provide new therapeutic targets for future anti-angiogenic treatment of glioma
Genetic polymorphisms of ATG5 (zeige ATG5 Antikörper) and ATG7 could contribute to neutrophilic airway inflammation in the pathogenesis of adult asthma.
Atg7 is critical for the survival of midbrain dopaminergic (mDA) neurons in physiological condition. Atg7 is up-regulated when exposed to MPTP (zeige PTPN2 Antikörper), but unlike in the control mice, chronic MPTP (zeige PTPN2 Antikörper) treatment did not lead to loss of mDA neurons in Atg7 conditional knockout mice. These results suggest that excessive Atg7-involved autophagy in the pathological condition has deleterious effects on the survival of mDA neurons.
It shows that AMBRA1 (zeige AMBRA1 Antikörper), but not ATG7, plays a role in TCR-mediated control of glycolytic factors and mitochondrial mass, while both AMBRA1 (zeige AMBRA1 Antikörper) and ATG7 are required for autolysosome formation.
Collectively, these data reveal that miR (zeige MLXIP Antikörper)-20a inhibits autophagic response and promotes BCG (zeige SLC11A1 Antikörper) survival in macrophages by targeting ATG7 and ATG16L1 (zeige ATG16L1 Antikörper).
Beta-Atg7 (-/-) mice had proinsulin (zeige INS Antikörper)-containing sequestosome 1 (p62 (zeige SQSTM1 Antikörper) [also known as SQSTM1 (zeige SQSTM1 Antikörper)])(+) aggregates in beta cells, indicating proinsulin (zeige INS Antikörper) is regulated by autophagy in vivo. Short-term bafilomycin-A1 treatment and ATG5 (zeige ATG5 Antikörper)/7 knockdown increased steady-state proinsulin (zeige INS Antikörper) and hormone precursor chromogranin A (zeige CHGA Antikörper) content. ATG5 (zeige ATG5 Antikörper)/7 knockdown also increased glucose- and non-fuel-stimulated insulin (zeige INS Antikörper) secretion.
gene deletion results in accumulation of RPE65 (zeige RPE65 Antikörper) variant M450 in the retinal pigment epithelium
A conditional deletion of Atg7 in hepatocytes leads to hepatomegaly and in aged animals to liver tumors.
this study shows that knockdown of ATG7 enhances macrophage-associated (zeige CD163 Antikörper) phagocytosis and intracellular killing of Pseudomonas aeruginosa
specific ablation of autophagy gene 7 (Atg7) from kidney proximal tubules worsened Lipopolysaccharide-induced acute kidney injury.
These findings reveal that selective neuronal deletion of Atg7 is strongly protective against neuronal death.
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
autophagy-related protein 7
, Autophagy-related protein 7
, ATG7 autophagy related 7 homolog
, ATG12-activating enzyme E1 ATG7
, ubiquitin activating enzyme E1-like protein
, ubiquitin-activating enzyme E1-like protein
, ubiquitin-like modifier-activating enzyme ATG7
, autophagy-related 7
, autophagy related 7 homolog
, potential E1-like Atg12p-Atg5p conjugation enzyme Atg7