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Human Polyclonal ATG7 Primary Antibody für IF, IHC (p) - ABIN388522
Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005
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Human Polyclonal ATG7 Primary Antibody für ICC, IF - ABIN269462
Park, Lee, Kim, Lee, Lee, Kim, Jang, Choi, Kwon, Kim: A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells. in Cancer research 2007
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Human Polyclonal ATG7 Primary Antibody für IHC (p), WB - ABIN4282130
Lee, Chen, Su, Chueh: Sirtuin 1 (SIRT1) Deacetylase Activity and NAD⁺/NADH Ratio Are Imperative for Capsaicin-Mediated Programmed Cell Death. in Journal of agricultural and food chemistry 2015
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Human Polyclonal ATG7 Primary Antibody für EIA, WB - ABIN118061
Aoki, Kobayashi, Tanida, Hatano, Komori, Matsumoto, Nishioka, Uemura: [A difficult case of esophageal and gastric double cancer with pleural and pericardial effusion following chemo-radiotherapy (CRT)] in Gan to kagaku ryoho. Cancer & chemotherapy 2008
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Human Polyclonal ATG7 Primary Antibody für IHC (p), WB - ABIN388521
Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005
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Human Monoclonal ATG7 Primary Antibody für WB - ABIN387793
Metzger, Saukko, Van Che, Tong, Puder, Riess, Nguyen: Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7. in Human genetics 2010
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Human Polyclonal ATG7 Primary Antibody für IHC (p), WB - ABIN388520
Greenberg: Degrade or die: a dual function for autophagy in the plant immune response. in Developmental cell 2005
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Human Polyclonal ATG7 Primary Antibody für IF, IHC (p) - ABIN388523
Levine: Eating oneself and uninvited guests: autophagy-related pathways in cellular defense. in Cell 2005
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PSMD10/gankyrin (zeige PSMD10 Antikörper) has a role in inducing autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression
the ATG5 (zeige ATG5 Antikörper)-ATG7-NCOA4 (zeige NCOA4 Antikörper) autophagic pathway has a role in ferroptosis
knockdown of autophagy genes ATG5 (zeige ATG5 Antikörper) or ATG7 resulted in reduced hematopoietic stem/progenitor cell frequencies in vitro as well as in vivo.
Nine of the 32 (28.1%) iCCA (zeige PRRT2 Antikörper) patients had gene mutations at chromosome 3p, totaling 11 mutations across five genes. Those included five (15.6%) BAP1 (zeige RNF2 Antikörper) mutations, two each (6.3%) of CACNA2D3 (zeige CACNA2D3 Antikörper) and RASSF1 (zeige RASSF1 Antikörper) mutations, and one each (3.1%) of ATG7 and PLCD1 (zeige PLCD1 Antikörper) mutations. Six (18.8%) cases had concurrent loss of chromosome 3p and gene mutations.
knockdown of ATG7 results in decreased glycolysis and increased flux of labeled carbons through the mitochondrial tricarboxylic acid cycle.
SNP rs11706903 in ATG7 was not associated with systemic lupus erythematosus I Chinese Han population.
low serum ATG7 is associated with ulcerative colitis
The U2AF35 (zeige U2AF1 Antikörper)(S34F) mutation alters interaction with CFIm59 (zeige CPSF7 Antikörper), leading to increased use of a distal cleavage and polyadenylation site in the ATG7 pre-mRNA, decreasing levels of ATG7 protein and defective autophagy, ultimately leading to transformation.
the inhibition of Atg7 appears to be a valid strategy to enhance chemosensitivity, and it could indeed improve outcomes in acute myeloid leukemia (zeige BCL11A Antikörper) therapy.
Our data demonstrate that HOTAIR promotes the activation of autophagy in HCC (zeige FAM126A Antikörper) cells by upregulating the expression of the autophagy-related genes ATG3 (zeige ATG3 Antikörper) and ATG7.
Autophagy deficiency induced by RPE (zeige RPE Antikörper)-specific deletion of Atg5 (zeige ATG5 Antikörper) or Atg7 predisposes but does not necessarily drive the development of AMD (zeige AMD1 Antikörper)-like phenotypes or retinal degeneration.
ATG7 has a role in autophagy deficiency in macrophages that may contribute to the progression of metabolic syndrome associated with lipid injury and colitis
ATG proteins ATG5 (zeige ATG5 Antikörper) and ATG7 may be required for phagosome maturation under some conditions, but are not universally required for this process
Autophagy and tumorigenesis were not increased in Atg7(+/-) mice kept in social isolation and fed OID. Thus, social isolation may increase breast cancer risk by inducing autophagy, independent of changes in body weight.
ATG7, but not ATG13 (zeige ATG13 Antikörper) or ULK1 (zeige ULK1 Antikörper) has a role in functional autophagy in glioblastoma development
Atg7 is critical for the survival of midbrain dopaminergic (mDA) neurons in physiological condition. Atg7 is up-regulated when exposed to MPTP (zeige PTPN2 Antikörper), but unlike in the control mice, chronic MPTP (zeige PTPN2 Antikörper) treatment did not lead to loss of mDA neurons in Atg7 conditional knockout mice. These results suggest that excessive Atg7-involved autophagy in the pathological condition has deleterious effects on the survival of mDA neurons.
It shows that AMBRA1 (zeige AMBRA1 Antikörper), but not ATG7, plays a role in TCR-mediated control of glycolytic factors and mitochondrial mass, while both AMBRA1 (zeige AMBRA1 Antikörper) and ATG7 are required for autolysosome formation.
Collectively, these data reveal that miR (zeige MLXIP Antikörper)-20a inhibits autophagic response and promotes BCG (zeige SLC11A1 Antikörper) survival in macrophages by targeting ATG7 and ATG16L1 (zeige ATG16L1 Antikörper).
Beta-Atg7 (-/-) mice had proinsulin (zeige INS Antikörper)-containing sequestosome 1 (p62 (zeige SQSTM1 Antikörper) [also known as SQSTM1 (zeige SQSTM1 Antikörper)])(+) aggregates in beta cells, indicating proinsulin (zeige INS Antikörper) is regulated by autophagy in vivo. Short-term bafilomycin-A1 treatment and ATG5 (zeige ATG5 Antikörper)/7 knockdown increased steady-state proinsulin (zeige INS Antikörper) and hormone precursor chromogranin A (zeige CHGA Antikörper) content. ATG5 (zeige ATG5 Antikörper)/7 knockdown also increased glucose- and non-fuel-stimulated insulin (zeige INS Antikörper) secretion.
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
autophagy-related protein 7
, Autophagy-related protein 7
, ATG7 autophagy related 7 homolog
, ATG12-activating enzyme E1 ATG7
, ubiquitin activating enzyme E1-like protein
, ubiquitin-activating enzyme E1-like protein
, ubiquitin-like modifier-activating enzyme ATG7
, autophagy-related 7
, autophagy related 7 homolog
, potential E1-like Atg12p-Atg5p conjugation enzyme Atg7