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anti-Human CSH1 Antikörper:
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Human Polyclonal CSH1 Primary Antibody für WB - ABIN1881233
Voorhees, Brooks: Obligate ordered binding of human lactogenic cytokines. in The Journal of biological chemistry 2010
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Human Polyclonal CSH1 Primary Antibody für IHC (fp), IHC (fro) - ABIN966856
MacDonald, Nicol, Belfield, Shah, Mack: Enzyme-linked immunoassay for placental lactogen in human serum. in Clinical chemistry 1980
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Human Monoclonal CSH1 Primary Antibody für IRMA - ABIN2476148
Schwarz, Berger, Wick: Epitope-selective, monoclonal-antibody-based immunoradiometric assays of predictable specificity for differential measurement of choriogonadotropin and its subunits. in Clinical chemistry 1985
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Placental lactogen is expressed but is not translated into protein in breast cancer.
These results indicate that placental lactogen induces CYP2E1 (zeige CYP2E1 Antikörper) expression via PI3-kinase (zeige PIK3CA Antikörper) pathway in human hepatocytes.
Expression of placental lactogen mRNA is increased in plasma of women with placenta previa and invasive placenta.
results are consistent with a pleiotropic effect of placental hGH/CSH genes at the maternal-fetal interface relating to the regulation of fetal growth and the risk of affected maternal metabolism.
Data conclude that members of the C/EBP (zeige CEBPA Antikörper) and Ets (zeige ETS1 Antikörper) families can differentially modulate CS-Benh and CS-Aenh activity.
hPL (zeige LGALS1 Antikörper)-A is involved in the regulation of pancreatic beta cells activity.
Results strongly support a conformationally mediated obligate-ordered prolactin receptor (zeige PRLR Antikörper) binding for each of the three lactogenic hormones: prolactin (zeige PRL Antikörper), growth hormone (zeige GH1 Antikörper), and placental lactogen.
The human growth hormone/chorionic somatomammotropin at chromosome 17 is implicated in regulation of postnatal and intrauterine growth.
Investigation of the GRB2 (zeige GRB2 Antikörper), GRB7 (zeige GRB7 Antikörper), and CSH1 genes as candidates for the Silver-Russell syndrome (SRS (zeige SMS Antikörper)) on chromosome 17q.
a role for CSH1 haploinsufficiency in the etiology of growth retardation
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation\; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.
, chorionic somatomammotropin A
, chorionic somatomammotropin hormone
, placental lactogen
, chorionic somatomammotropin hormone 1 (placental lactogen)
, placental lactogen I
, placental lactogen II
, Placental lactogen-1
, chorionic somatomammotropin hormone 1
, placental lactogen 1
, placental lactogen-I alpha
, prolactin-like 2