anti-Schwein s100b Antikörper für Enzyme Immunoassay

Recommended s100b Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
S100 Calcium Binding Protein B (S100B) Antikörper
  • AI266795
  • S100
  • S100a
  • NEF
  • S100-B
  • S100beta
  • S100P
  • AI850290
  • Bpb
  • S100 calcium binding protein A1
  • S100 calcium binding protein B
  • S100 protein, beta polypeptide, neural
  • S100a1
  • S100B
  • S100b
Reaktivität
Katze, Rind (Kuh), Human, Schwein, Kaninchen, Ratte (Rattus)
446
261
227
202
43
31
7
2
2
1
1
1
1
1
Wirt
Maus
294
184
8
4
3
Klonalität
Monoklonal
Konjugat
Dieser s100b Antikörper ist unkonjugiert
33
27
16
13
13
12
11
10
10
10
10
10
10
10
10
9
6
4
4
3
3
2
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
361
237
221
203
184
177
130
24
13
13
9
7
5
4
4
2
2
1
1
Hersteller
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Produktnummer ABIN114579
$ 346.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN114578 EIA IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen SH-B1

General

Antigen S100 Calcium Binding Protein B (S100B) Antikörper
Reaktivität Katze, Rind (Kuh), Human, Schwein, Kaninchen, Ratte (Rattus)
(446), (261), (227), (202), (43), (31), (7), (2), (2), (1), (1), (1), (1), (1)
Wirt Maus
(294), (184), (8), (4), (3)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser s100b Antikörper ist unkonjugiert
(33), (27), (16), (13), (13), (12), (11), (10), (10), (10), (10), (10), (10), (10), (10), (9), (6), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(361), (237), (221), (203), (184), (177), (130), (24), (13), (13), (9), (7), (5), (4), (4), (2), (2), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-s100b Antikörper

Target Details s100b Anwendungsinformationen Handhabung Referenzen für anti-s100b Antikörper (ABIN114579) Bilder
Spezifität This antibody is specific against an epitope located on the beta chain but not on the alpha chain of S-100 (i.e. in S-100a and S-100ao). This antibody can be used to localize S-100a and S-100b in various tissue sections.
Cellular Localization:Cytoplasmic.
Reinigung Ascites
Immunogen Purified bovine brain S-100b preparation.
Klon SH-B1
Isotyp IgG1

Target Details s100b

Produktdetails anti-s100b Antikörper Anwendungsinformationen Handhabung Referenzen für anti-s100b Antikörper (ABIN114579) Bilder zurück nach oben
Antigen
Andere Bezeichnung S100B (S100B Antibody Abstract)
Hintergrund S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin.Synonyms: Astrocyte Marker, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 beta, S100 calcium-binding protein B
Gen-ID 6285
NCBI Accession NP_006263
UniProt P04271
Pathways Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity

Anwendungsinformationen

Produktdetails anti-s100b Antikörper Target Details s100b Handhabung Referenzen für anti-s100b Antikörper (ABIN114579) Bilder zurück nach oben
Applikationshinweise Immunohistochemistry on Paraffin Sections: Dilute 1/50-1/100 in an ABC method (30 minutes at room temperature). Proteolytic digestion of tissue sections is required prior to immunostaining. Recommended Positive Control: Melanoma. Also suitable for ELISA and Blot (denaturating conditions).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-s100b Antikörper Target Details s100b Anwendungsinformationen Referenzen für anti-s100b Antikörper (ABIN114579) Bilder zurück nach oben
Format Liquid
Lagerung 4 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C.

Referenzen für anti-s100b Antikörper (ABIN114579)

Produktdetails anti-s100b Antikörper Target Details s100b Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Kan-Mitchell, Rao, Albert, Van Eldik, Taylor: "S100 immunophenotypes of uveal melanomas." in: Investigative ophthalmology & visual science, Vol. 31, Issue 8, pp. 1492-6, 1990

Baudier, Glasser, Gerard: "Ions binding to S100 proteins. I. Calcium- and zinc-binding properties of bovine brain S100 alpha alpha, S100a (alpha beta), and S100b (beta beta) protein: Zn2+ regulates Ca2+ binding on S100b protein." in: The Journal of biological chemistry, Vol. 261, Issue 18, pp. 8192-203, 1986

Takahashi, Isobe, Ohtsuki, Akagi, Sonobe, Okuyama: "Immunohistochemical study on the distribution of alpha and beta subunits of S-100 protein in human neoplasm and normal tissues." in: Virchows Archiv. B, Cell pathology including molecular pathology, Vol. 45, Issue 4, pp. 385-96, 1984

Mani, Boyes, Kay: "Physicochemical and optical studies on calcium- and potassium-induced conformational changes in bovine brain S-100b protein." in: Biochemistry, Vol. 21, Issue 11, pp. 2607-12, 1982