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anti-WWTR1 (WWTR1) Antikörper

Bezeichnung:
anti-WW Domain Containing Transcription Regulator 1 Antikörper (WWTR1)
Auf www.antikoerper-online.de finden Sie aktuell 50 WW Domain Containing Transcription Regulator 1 (WWTR1) Antikörper von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen WWTR1 Proteine (5) und WWTR1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 61 WWTR1 Produkte verfügbar.
Synonyme:
2310058J06Rik, 2610021I22Rik, C78399, Taz, WWTR1
Alle Antikörper anzeigen Gen GeneID UniProt
WWTR1 25937 Q9GZV5
WWTR1 97064 Q9EPK5
WWTR1 295062  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-WWTR1 (WWTR1) Antikörper

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anti-Human WWTR1 Antikörper:

anti-Mouse (Murine) WWTR1 Antikörper:

anti-Rat (Rattus) WWTR1 Antikörper:

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Am meisten referenzierte anti-WWTR1 Antikörper

  1. Human Polyclonal WWTR1 Primary Antibody für WB - ABIN153163 : Chan, Lim, Guo, Ng, Lee, Hunziker, Zeng, Hong: A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. in Cancer research 2008 (PubMed)
    Zeige alle 8 Referenzen für ABIN153163

  2. Human Polyclonal WWTR1 Primary Antibody für ChIP, ICC - ABIN258561 : Strakova, Reed, Ihnatovych: Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization. in Biology of reproduction 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN258561

  3. Human Polyclonal WWTR1 Primary Antibody für EIA, WB - ABIN955592 : Remue, Meerschaert, Oka, Boucherie, Vandekerckhove, Sudol, Gettemans: TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner. in FEBS letters 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN955592

  4. Cow (Bovine) Polyclonal WWTR1 Primary Antibody für WB - ABIN2779708 : Hong, Hwang, McManus, Amsterdam, Tian, Kalmukova, Mueller, Benjamin, Spiegelman, Sharp, Hopkins, Yaffe: TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. in Science (New York, N.Y.) 2005 (PubMed)

Weitere Antikörper gegen WWTR1 Interaktionspartner

Zebrafish WW Domain Containing Transcription Regulator 1 (WWTR1) Interaktionspartner

  1. Yap (zeige YAP1 Antikörper)/Taz (zeige TAZ Antikörper)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.

  2. Taz (zeige TAZ Antikörper) is required in the anteroposterior patterning of the pronephric progenitor domain in the intermediate mesoderm, acting in part by regulating retinoic acid signaling in the pronephric progenitor field in the intermediate mesoderm.

  3. Taz (zeige TAZ Antikörper)-depleted larvae displayed patterning defects in ventral cranial vessels that correlate with lateral displacement of thyroid follicles

  4. When transcriptional coactivators Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.

  5. TAZ (zeige TAZ Antikörper) has a critical role in osteoblast differentiation in vivo

Human WW Domain Containing Transcription Regulator 1 (WWTR1) Interaktionspartner

  1. thromboxane A2 signaling activates YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) to promote Vascular Smooth Muscle migration and proliferation, indicating YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) as potential therapeutic targets for cardiovascular diseases.

  2. Paralog of TAZ (zeige TAZ Antikörper) (YAP (zeige YAP1 Antikörper)) expression can be upregulated by TAZ (zeige TAZ Antikörper) inhibition which leads to EGFRI resistance.

  3. Studies indicates that YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) are essential for cancer initiation or growth of most solid tumors. Their activation induces cancer stem cell attributes, proliferation, chemoresistance, and metastasis. YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) are sensors of the structural and mechanical features of the cell microenvironment. [review]

  4. Thus, it could be concluded that EPO (zeige EPO Antikörper) and IGF1 (zeige IGF1 Antikörper) possessed a potent synergism in promoting osteogenic differentiation, and the synergism was mainly attributed to co-regulation of different osteogenic regulators PPARgamma (zeige PPARG Antikörper) and TAZ (zeige TAZ Antikörper), which were targeted genes of EPO (zeige EPO Antikörper) and IGF1 (zeige IGF1 Antikörper) respectively.

  5. eIF5A (zeige EIF5 Antikörper)-PEAK1 (zeige PEAK1 Antikörper) signaling controls YAP1 (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) expression, which is associated with increased pancreatic ductal adenocarcinoma tumorigenicity

  6. Our goal is to describe the physiological roles of Hippo signaling in several normal organ systems, as well as to emphasize how disruption of the Hippo pathway, and particularly hyperactivation of YAP1 (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper), can be oncogenic (review)

  7. miR (zeige MLXIP Antikörper)-125a-5p functions as an important tumor suppressor that suppresses the EGFR (zeige EGFR Antikörper) pathway by targeting TAZ (zeige TAZ Antikörper) to inhibit tumor progression in retinoblastoma.

  8. results demonstrate that skeletal stem/stromal cell mobilize Snail (zeige SNAI1 Antikörper)/Slug (zeige SNAI2 Antikörper)-YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) complexes to control stem cell function

  9. TAZ (zeige TAZ Antikörper) is significantly associated with poor survival in embryonal rhabdomyosarcoma. Constitutively active TAZ (zeige TAZ Antikörper) S89A significantly increased proliferation of C2C12 myoblasts and, importantly, colony formation on soft agar, suggesting transformation. However, TAZ (zeige TAZ Antikörper) then switches to enhance myogenic differentiation in C2C12 myoblasts.

  10. SCLC cell lines of the YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) subgroup had higher sensitivity to the widely used anticancer agent for SCLC, topotecan.

Mouse (Murine) WW Domain Containing Transcription Regulator 1 (WWTR1) Interaktionspartner

  1. both Snail (zeige SNAI1 Antikörper) and Slug (zeige SNAI2 Antikörper) are able to form binary complexes with either YAP (zeige YAP1 Antikörper) or TAZ (zeige TAZ Antikörper) that, together, control YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) transcriptional activity and function throughout mouse development.

  2. results demonstrate that skeletal stem/stromal cell mobilize Snail (zeige SNAI1 Antikörper)/Slug (zeige SNAI2 Antikörper)-YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) complexes to control stem cell function

  3. Results found that sclerostin (zeige SOST Antikörper) enhances adipocyte differentiation in 3T3-L1 cells and reduced TAZ (zeige TAZ Antikörper)-responsive transcriptional activity and TAZ (zeige TAZ Antikörper)-responsive gene expression, indicating a role for TAZ (zeige TAZ Antikörper) as a regulator of adipogenesis by sclerostin (zeige SOST Antikörper).

  4. Expression of TAZ (zeige TAZ Antikörper) promotes embryonic neural stem cell maintenance by enhancing stemness of neural stem cells during mammalian brain development.

  5. Tead2 (zeige TEAD2 Antikörper) transcription factors are crucial regulators of the cellular distribution of Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper), and together they control the expression of genes critical for EMT (zeige ITK Antikörper) and metastasis.

  6. findings uncover important roles for Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper) in cranial neural crest diversification and development

  7. Study discovered that YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) are bona fide downstream effectors of the alternative Wnt (zeige WNT2 Antikörper) signaling pathway.

  8. Hippo signalling effectors, YAP (zeige YAP1 Antikörper) and TAZ (zeige TAZ Antikörper), promote both the proliferation of intestinal stem/progenitor cells and their differentiation into goblet cells.

  9. This study identifies a novel mechanism of TAZ (zeige TAZ Antikörper) regulation by YAP (zeige YAP1 Antikörper), which has significant implications for our understanding of Hippo pathway regulation, YAP (zeige YAP1 Antikörper)-isoform specific signaling, and the role of these proteins in cell proliferation, apoptosis, and tumorigenesis

  10. Disrupting Yap (zeige YAP1 Antikörper)/Taz (zeige TAZ Antikörper) activities enhances Ret (zeige RET Antikörper) pathway activity and contributes to pathogenesis of lower urinary tract defects

WWTR1 Antigen-Profil

Beschreibung des Gens

This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with WWTR1

  • WW domain containing transcription regulator 1 (wwtr1) Antikörper
  • WW domain containing transcription regulator 1 (WWTR1) Antikörper
  • WW domain containing transcription regulator 1 (Wwtr1) Antikörper
  • 2310058J06Rik Antikörper
  • 2610021I22Rik Antikörper
  • C78399 Antikörper
  • Taz Antikörper
  • WWTR1 Antikörper

Bezeichner auf Proteinebene für WWTR1

WW domain containing transcription regulator 1 , WW domain-containing transcription regulator protein 1 , taz , WW domain-containing transcription regulator protein 1-like , transcriptional co-activator with PDZ-binding motif , transcriptional coactivator with PDZ-binding motif , transcriptional coactivator with PDZ binding motif , transcriptional co-activator with PDZ-binding motif (TA)Z , transcriptional co-activator with PDZ-binding motif (TAZ)

GENE ID SPEZIES
496155 Xenopus laevis
568008 Danio rerio
100050661 Equus caballus
100401831 Callithrix jacchus
100437619 Pongo abelii
100493170 Xenopus (Silurana) tropicalis
100522573 Sus scrofa
100592028 Nomascus leucogenys
25937 Homo sapiens
609743 Canis lupus familiaris
614786 Bos taurus
97064 Mus musculus
295062 Rattus norvegicus
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