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TNFRSF21 Proteine (TNFRSF21)

Bezeichnung:
Tumor Necrosis Factor Receptor Superfamily, Member 21 Proteine (TNFRSF21)
Auf www.antikoerper-online.de finden Sie aktuell 40 Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Proteine von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFRSF21 Antikörper (167) und TNFRSF21 Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 228 TNFRSF21 Produkte verfügbar.
Synonyme:
AA959878, BM-018, CD358, dr6, im:6795346, MGC146356, R74815, tnfrsf21, TR7, wu:fa55e01, wu:fb02e11, wu:fc29a09, wu:fi27h08
alle Proteine anzeigen Gen GeneID UniProt
TNFRSF21 27242 O75509
TNFRSF21 94185 Q9EPU5
TNFRSF21 316256  

Weitere Synonyme anzeigen

TNFRSF21 Proteine (TNFRSF21) nach Spezies

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Am meisten referenzierte TNFRSF21 Proteine

  1. Human TNFRSF21 Protein expressed in Human Cells - ABIN2002244 : Kasof, Lu, Liu, Speer, Mongan, Gomes, Lorenzi: Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB. in Oncogene 2001 (PubMed)
    Zeige alle 5 Referenzen für ABIN2002244

  2. Cynomolgus TNFRSF21 Protein expressed in Human Cells - ABIN2010155 : Pan, Bauer, Haridas, Wang, Liu, Yu, Vincenz, Aggarwal, Ni, Dixit: Identification and functional characterization of DR6, a novel death domain-containing TNF receptor. in FEBS letters 1998 (PubMed)
    Zeige alle 5 Referenzen für ABIN2010155

  3. Human TNFRSF21 Protein expressed in Human Cells - ABIN2002248 : Zhao, Yan, Wang, Erickson, Grewal, Dixit: Impaired c-Jun amino terminal kinase activity and T cell differentiation in death receptor 6-deficient mice. in The Journal of experimental medicine 2001 (PubMed)
    Zeige alle 5 Referenzen für ABIN2002248

  4. Mouse (Murine) TNFRSF21 Protein expressed in Human Cells - ABIN2007584 : Liu, Heuer, Na, Galbreath, Zhang, Yang, Glasebrook, Song: Accelerated onset and increased severity of acute graft-versus-host disease following adoptive transfer of DR6-deficient T cells. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Zeige alle 5 Referenzen für ABIN2007584

Weitere Proteine zu TNFRSF21 Interaktionspartnern

Human Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Interaktionspartner

  1. Knockdown death receptor 6 by shRNA in human pDCs cell line GEN2.2 significantly diminished the CpG-ODN induced IFN-regulatory factor 7 nuclear localization and IFN-I production.

  2. data identify a new mechanism underlying tumour cell extravasation and metastasis, and suggest endothelial DR6-mediated necroptotic signalling pathways as targets for anti-metastatic therapies

  3. Increase in the expression levels of mRNA and protein for the death receptor 6 is associated with various types of gynaecological malignancy.

  4. Circulating levels of DR6 and Gpm6B (zeige GPM6B Proteine) correlate with breast cancer tumor grade.

  5. The present findings suggested that DR6 is involved in the pathogenesis of endometriosis by creating the proliferative and anti-apoptotic characteristics of endometriosis.

  6. Our results support the view that DR6 functions with APP (zeige APP Proteine) to modulate synaptic density in the adult CNS

  7. These results provide direct support for the model that APP (zeige APP Proteine) and DR6 function cell autonomously and in the same pathway to control pruning

  8. our findings provide new insight into a novel mechanism by which DR6 induces downstream signaling in response to an agonist antibody.

  9. DR6 knockout mice are viable and fertile, and show hyperproliferation of T cells when stimulated.

  10. DR6 mediates T cell proliferation and differentiation in mice.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Interaktionspartner

  1. data identify a new mechanism underlying tumour cell extravasation and metastasis, and suggest endothelial DR6-mediated necroptotic signalling pathways as targets for anti-metastatic therapies

  2. This study demonistrated that DR6 to contribute to axonal pruning occurring during experience-dependent cortical plasticity throughout life.

  3. A DR6/p75(NTR (zeige NGFR Proteine)) complex is responsible for beta-amyloid-induced cortical neuron death.

  4. Pla2g7 (zeige Lp-PLA2 Proteine) and Tnfrsf21 have been identified as genetic susceptibility to influenza genes in mice.

  5. findings show that DR6 expression is significantly but transiently upregulated only in activated both CD4 (zeige CD4 Proteine)+ and CD8 (zeige CD8A Proteine)+ T cells in NF-kappaB (zeige NFKB1 Proteine) and NF-AT (zeige NFATC3 Proteine) dependent manner with a contribution of PI3K-dependent signaling

  6. T cells lacking the DR6 receptor generate a severe form of acute graft-versus-host disease with accelerated onset, increased severity, rapid weight loss, and earlier organ damage and mortality.

  7. Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6.

  8. Death receptor 6 plays an important role in regulating leukocyte infiltration and function in the induction and progression of experimental autoimmune encephalomyelitis.

  9. point to a critical role of DR6 in regulating airway inflammation in the ovalbumin (zeige OVA Proteine)-induced mouse model of asthma

  10. results indicate that APP (zeige APP Proteine) and DR6 are components of a neuronal self-destruction pathway, and suggest that an extracellular fragment of APP (zeige APP Proteine), acting via DR6 and caspase 6 (zeige CASP6 Proteine), contributes to Alzheimer's disease

TNFRSF21 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.

Alternative names and synonyms associated with TNFRSF21

  • tumor necrosis factor receptor superfamily, member 21 (TNFRSF21)
  • tumor necrosis factor receptor superfamily, member 21 (tnfrsf21)
  • tumor necrosis factor receptor superfamily, member 21 (LOC100224578)
  • tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21)
  • AA959878 Protein
  • BM-018 Protein
  • CD358 Protein
  • dr6 Protein
  • im:6795346 Protein
  • MGC146356 Protein
  • R74815 Protein
  • tnfrsf21 Protein
  • TR7 Protein
  • wu:fa55e01 Protein
  • wu:fb02e11 Protein
  • wu:fc29a09 Protein
  • wu:fi27h08 Protein

Bezeichner auf Proteinebene für TNFRSF21

tumor necrosis factor receptor superfamily, member 21 , tumor necrosis factor receptor superfamily member 21-like , TNFR-related death receptor 6 , death receptor 6 , tumor necrosis factor receptor superfamily member 21 , Death receptor 6 , TNFR-related death receptor-6

GENE ID SPEZIES
462749 Pan troglodytes
705101 Macaca mulatta
780059 Xenopus (Silurana) tropicalis
100224578 Taeniopygia guttata
100349758 Oryctolagus cuniculus
100386273 Callithrix jacchus
100459882 Pongo abelii
100554405 Anolis carolinensis
27242 Homo sapiens
609964 Canis lupus familiaris
537922 Bos taurus
94185 Mus musculus
316256 Rattus norvegicus
422062 Gallus gallus
564874 Danio rerio
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