anti-Hund Unc-13 Homolog D (C. Elegans) Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended Unc-13 Homolog D (C. Elegans) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Unc-13 Homolog D (C. Elegans) (UNC13D) Antikörper
  • FHL3
  • HLH3
  • HPLH3
  • Munc13-4
  • UNC13D
  • 2610108D09Rik
  • Jinx
  • mFLJ00067
  • Unc13h4
  • unc-13 homolog D
  • unc-13 homolog D (C. elegans)
  • UNC13D
  • Unc13d
  • unc13d
  • un13d
Epitop
Internal Region
23
7
5
4
3
3
3
2
1
1
Reaktivität
Hund, Human, Maus, Ratte (Rattus)
58
13
5
4
3
3
2
2
1
1
Wirt
Ziege
30
19
10
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
45
32
15
11
8
7
1
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN374716
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1740584 IHC (p) ELISA Goat Internal Region Anmelden zum Anzeigen Polyclonal

General

Antigen Unc-13 Homolog D (C. Elegans) (UNC13D) Antikörper
Epitop Internal Region
(23), (7), (5), (4), (3), (3), (3), (2), (1), (1)
Reaktivität Hund, Human, Maus, Ratte (Rattus)
(58), (13), (5), (4), (3), (3), (2), (2), (1), (1)
Wirt Ziege
(30), (19), (10)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(45), (32), (15), (11), (8), (7), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Spezifität This antibody reacts to Munc13-4 / UNC13D.
Kreuzreaktivität (Details) Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.
Reinigung Affinity chromatography
Immunogen Peptide with sequence C-ETQKHKKDLHPLFD, from the internal region of the protein sequence

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung UNC13D (UNC13D Antibody Abstract)
Hintergrund Secretion of the contents of cytolytic granules at the immunologic synapse is a highly regulated process essential for lymphocyte cytotoxicity. This process requires the rapid transfer of perforin containing lytic granules to the target cell interface, followed by their docking and fusion with the plasma membrane. Munc 13-4 localises with cytotoxic granules at the immunologic synapse. Munc 13-4 is essential for the priming step of cytolytic granule secretion preceding vesicle membrane fusion. There are two named isoforms.Synonyms: Munc13-4, Protein unc-13 homolog D
Gen-ID 201294, 9606
UniProt Q70J99
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise ELISA: 1/128000. Western Blot: 1 - 3 μg/mL. Immunohistochemistry on paraffin sections: 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Zur Stadt, Beutel, Kolberg, Schneppenheim, Kabisch, Janka, Hennies: "Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A." in: Human mutation, Vol. 27, Issue 1, pp. 62-8, 2005

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
 image for anti-Unc-13 Homolog D (C. Elegans) (UNC13D) (Internal Region) antibody (ABIN374716) anti-Unc-13 Homolog D (C. Elegans) (UNC13D) (Internal Region) antibody
 image for anti-Unc-13 Homolog D (C. Elegans) (UNC13D) (Internal Region) antibody (ABIN374716) anti-Unc-13 Homolog D (C. Elegans) (UNC13D) (Internal Region) antibody (Image 2)