Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Proteine (TNFSF13)

Bezeichnung:
Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Proteine (TNFSF13)
Auf www.antikoerper-online.de finden Sie aktuell 36 Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) Proteine von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Antikörper (173) und Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Kits (38) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 260 Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Produkte verfügbar.
Synonyme:
2310026N09Rik, ANP32B, April, CD256, SLAN, TALL-2, Tall2, tnf13, TNFSF12-TNFSF13, TNFSF13, TRDL-1, Trdl1, ZTNF2
alle Proteine anzeigen Gen GeneID UniProt
TNFSF13 8741 O75888
TNFSF13 69583 Q9D777
TNFSF13 287437  

Weitere Synonyme anzeigen

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Am meisten referenzierte Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Proteine

  1. Human TNFSF13 Protein expressed in Escherichia coli (E. coli) - ABIN2667376 : Bossen, Ingold, Tardivel, Bodmer, Gaide, Hertig, Ambrose, Tschopp, Schneider: Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. in The Journal of biological chemistry 2006 (PubMed)
    Zeige alle 13 Referenzen für 2667376

  2. Human TNFSF13 Protein expressed in HEK-293 Cells - ABIN1344412 : Litinskiy, Nardelli, Hilbert, He, Schaffer, Casali, Cerutti: DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. in Nature immunology 2002 (PubMed)
    Zeige alle 9 Referenzen für 1344412

  3. Human TNFSF13 Protein expressed in Wheat germ - ABIN1323221 : Chihara, Aranami, Sato, Miyazaki, Miyake, Okamoto, Ogawa, Toda, Yamamura: Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica. in Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)

Weitere Proteine zu Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Interaktionspartnern

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) Interaktionspartner

  1. ApoE-/-APRIL-Tg mice have increased oxLDL-specific serum IgM levels, potentially mediated via an increase in B1a lymphocytes

  2. Results showed that chemokine (zeige CCL1 Proteine)-mediated recruitment of neutrophils secreting the tumor-promoting factor APRIL mediates DLBCL progression.

  3. This study showed that both BAFF (zeige TNFSF13B Proteine) and APRIL levels were increased in CSF (zeige CSF2 Proteine) of patients with anti-NMDAR (zeige GRIN1 Proteine) encephalitis.

  4. New molecular mechanisms of in vivo Multiple Myeloma (MM) growth and immunosuppression critically dependent on BCMA (zeige TNFRSF17 Proteine) and APRIL in the Bone marrow microenvironment, further supporting targeting this prominent pathway in MM.

  5. Urinary APRIL (uAPRIL) and BAFF (zeige TNFSF13B Proteine) (uBAFF) levels were raised significantly in AN.

  6. Data did not detect any significant association with SNPs of APRIL, SPATA8, PDGFRA, and POLB with Systemic Lupus Erythematosus in Chinese Han Population.

  7. Recombinant human APRIL (rhAPRIL) could rescue HCC (zeige FAM126A Proteine) cell proliferation inhibited by miR (zeige MLXIP Proteine)-383.

  8. Host-derived proteins pp32 and APRIL interact with a free form of influenza virus RNA-dependent RNA polymerase and preferentially upregulates viral RNA synthesis rather than cRNA synthesis.

  9. high expression of APRIL in clear cell renal cell carcinoma (zeige MOK Proteine) was correlated with high Fuhrman nuclear grade, high pathologic stage, and poor overall and cancer-specific survival of the patients

  10. TNFSF13 and FDX1 have potential roles in IgAN in the Han Chinese population. This information may be useful in the development of early prognostics for IgAN.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) Interaktionspartner

  1. this study identifies APRIL as a new target involved in B-cell activation (zeige BLNK Proteine), in the maintenance of plasma cell survival and subsequent increased autoantibody production that sustains lupus development in mice

  2. this is the first study to implicate the APRIL signal transduction pathway in the pathogenesis of nephrogenic IgA production. Moreover, our findings identify APRIL as a potential target of therapy.

  3. the elevated presence of APRIL and BLyS (zeige TNFSF13B Proteine) in B cell-rich areas of chronically inflamed gingiva suggests that these cytokines may contribute to bone loss by promoting the survival and persistence of RANKL (zeige TNFSF11 Proteine)-expressing B cells/plasma cells.

  4. B cell activating factor (BAFF (zeige TNFSF13B Proteine)) and a proliferation inducing ligand (APRIL) mediate CD40 (zeige CD40 Proteine)-independent help by memory CD4 (zeige CD4 Proteine) T cells in transplantations.

  5. Heteromers consisting of one BAFF (zeige TNFSF13B Proteine) and two APRIL bind to receptor TACI (zeige TNFRSF13B Proteine), BCMA (zeige TNFRSF17 Proteine) but not to BAFFR (zeige TNFRSF13C Proteine).

  6. Immunization of mice with a DNA vaccine encoding BAFF (zeige TNFSF13B Proteine) or APRIL multitrimers, together with interleukin 12 and membrane-bound HIV-1 Env (zeige ERVW-1 Proteine) gp140, induced neutralizing antibodies against tier 1 and tier 2 (vaccine strain) viruses.

  7. APRIL selectively enhances axonal growth by activating ERK signaling and PI3-kinase/Akt/GSK-3beta signaling.

  8. Data indicate that APRIL expression accelerates the onset of TCL1 (zeige TCL1A Proteine)-driven leukemia formation mainly through TACI (zeige TNFRSF13B Proteine) activation.

  9. The ability of TACI (zeige TNFRSF13B Proteine)-Fc to activate reverse signalling through BAFF (zeige TNFSF13B Proteine) and APRIL, was investigated.

  10. CD1d (zeige CD1D Proteine)-restricted invariant NKT (zeige CTSL1 Proteine) cell-derived BAFF (zeige TNFSF13B Proteine) and APRIL each contribute to survival of plasma cells induced by immunization.

Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified\; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

Alternative names and synonyms associated with Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13)

  • tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13)
  • SLAN protein (SLAN)
  • TNF superfamily member 13 (april)
  • TNFSF12-TNFSF13 readthrough transcript (TNFSF12-TNFSF13)
  • tumor necrosis factor (ligand) superfamily, member 13 (tnfsf13)
  • a proliferation-inducing ligand (APRIL)
  • tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13)
  • 2310026N09Rik Protein
  • ANP32B Protein
  • April Protein
  • CD256 Protein
  • SLAN Protein
  • TALL-2 Protein
  • Tall2 Protein
  • tnf13 Protein
  • TNFSF12-TNFSF13 Protein
  • TNFSF13 Protein
  • TRDL-1 Protein
  • Trdl1 Protein
  • ZTNF2 Protein

Bezeichner auf Proteinebene für TNFSF13

tumor necrosis factor ligand superfamily member 13 , tumor necrosis factor ligand superfamily member 13 isoform alpha proprotein , SLAN protein , Acidic leucine-rich nuclear phosphoprotein 32 family member B , TNF superfamily member 13 , TNFSF12-TNFSF13 readthrough transcript , tumor necrosis factor superfamily member 13 , tumor necrosis factor (ligand) superfamily, member 13 , TNF- and APOL-related leukocyte expressed ligand 2 , a proliferation-inducing ligand , tumor necrosis factor-like protein ZTNF2 , tumor necrosis factor-related death ligand-1 , A proliferation-inducing ligand

GENE ID SPEZIES
100551507 Macaca mulatta
494442 Ovis aries
100136706 Oncorhynchus mykiss
479484 Canis lupus familiaris
749008 Pan troglodytes
100196575 Salmo salar
100434469 Pongo abelii
100551504 Pan troglodytes
100551510 Callithrix jacchus
100551512 Monodelphis domestica
100127162 Sus scrofa
8741 Homo sapiens
69583 Mus musculus
287437 Rattus norvegicus
538567 Bos taurus
100860886 Capra hircus
100568281 Canis lupus familiaris
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