Tubby Like Protein 3 Proteine (TULP3)

Auf www.antikoerper-online.de finden Sie aktuell 3 Tubby Like Protein 3 (TULP3) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Tubby Like Protein 3 Antikörper (51) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 59 Tubby Like Protein 3 Produkte verfügbar.
2310022L06Rik, AI316887, DKFZp469I1734, TUBL3
alle Proteine anzeigen Gen GeneID UniProt
TULP3 7289 O75386
Maus TULP3 TULP3 22158 O88413
Ratte TULP3 TULP3 688749  

Tubby Like Protein 3 Proteine (TULP3) nach Spezies

Weitere Proteine zu Tubby Like Protein 3 Interaktionspartnern

Human Tubby Like Protein 3 (TULP3) Interaktionspartner

  1. Data demonstrated that pancreatic cancer patients exhibiting high transcriptional levels of TULP3 showed a poor overall survival rate.

Mouse (Murine) Tubby Like Protein 3 (TULP3) Interaktionspartner

  1. loss of Zfp423 alters expression of several genes encoding key cilium components, including increased expression of Tulp3. Tulp3 is a direct binding target of Zfp423 and reducing the overexpression of Tulp3 in Zfp423-deficient cells suppresses Smoothened translocation defects.

  2. Tubby-like protein 3 (TULP3) binds to the IFT-A complex

  3. Tulp3 is a novel negative regulator of the Shh (zeige SHH Proteine) pathway.

  4. TULP3 is required proper for Shh (zeige SHH Proteine)-dependent limb patterning.

  5. This work uncovers a novel role for Tulp3 as a negative regulatory factor in the hedgehog (zeige SHH Proteine) pathway.

Tubby Like Protein 3 (TULP3) Protein Überblick

Protein Überblick

This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with Tubby Like Protein 3 (TULP3)

  • tubby like protein 3 (TULP3)
  • tubby like protein 3 (tulp3)
  • tubby-like protein 3 (Tulp3)
  • 2310022L06Rik Protein
  • AI316887 Protein
  • DKFZp469I1734 Protein
  • TUBL3 Protein

Bezeichner auf Proteinebene für Tubby Like Protein 3 Proteine (TULP3)

tubby like protein 3 , tubby-related protein 3 , tubby-like protein 3

451753 Pan troglodytes
709100 Macaca mulatta
100144732 Xenopus (Silurana) tropicalis
100173114 Pongo abelii
7289 Homo sapiens
516380 Bos taurus
611832 Canis lupus familiaris
426085 Gallus gallus
22158 Mus musculus
688749 Rattus norvegicus
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