anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) Antikörper

Bezeichnung:
anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Antikörper (PPP1R9B)
Auf www.antikoerper-online.de finden Sie aktuell 49 Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) Antikörper von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Kits (9) und Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 63 Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Produkte verfügbar.
Synonyme:
Neb2, PPP1R6, PPP1R9, SPINO, SPL, Spn

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Am meisten referenzierte anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Antikörper

  1. Human Polyclonal PPP1R9B Primary Antibody für EIA, WB - ABIN953658 : Sagara, Kawasaki, Iemura, Natsume, Takai, Akiyama: Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration. in Oncogene 2009 (PubMed)
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Weitere Antikörper gegen Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Interaktionspartner

Human Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) Interaktionspartner

  1. Data identify Spn (zeige SPN Antikörper) as a critical adhesion and signaling protein that is essential for modulating glioblastoma cell invasion in the brain microenvironment. Spn (zeige SPN Antikörper) suppresses brain tumor cell invasion, in part, via control of Rac1 GTPase (zeige RACGAP1 Antikörper) activities and invadopodia disassembly. Its C-terminus binds directly to the beta 8 integrin cytoplasmic tail.

  2. results indicate that spinophilin plays an important role in regulating the activity of Group I mGluRs as well as their influence on synaptic activity.

  3. Low spinophilin expression enhances aggressive biological behavior of breast cancer.

  4. Colorectal carcinoma expression of spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance.

  5. spinophilin might play a previously unrecognized role in the pathogenesis of head and neck squamous cell carcinoma

  6. Spn (zeige SPN Antikörper) downregulation contributes to a more aggressive biologic behavior, induces chemoresistance, and is associated with a poorer survival in patients with advanced stages of colorectal carcinoma.

  7. study found a substantial number of hepatocellular carcinomas (HCC (zeige FAM126A Antikörper)) show reduced or absent Spn (zeige SPN Antikörper) expression; the low expression of Spn (zeige SPN Antikörper) in tumour tissue is an independent negative prognostic factor for clinical outcome in HCC (zeige FAM126A Antikörper); spinophilin expression inversely correlates with proliferative activity

  8. Studies suggest that any change in substrate specificity of the spinophilin : PP1 (zeige PPA1 Antikörper) holoenzyme complex was probably due to direct modification of a PP1 (zeige PPA1 Antikörper) substrate binding surface.

  9. Spinophilin associates with both delta- and mu-OmicronR and G protein subunits in HEK293 cells participating in a multimeric signaling complex that displays a differential regulatory role in opioid receptor signaling.

  10. Spinophilin-deficient mice have enhanced antidepressant response to desipramine compared with wild-type controls.

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) Interaktionspartner

  1. two homologs neurabin and spinophilin play important yet distinct roles in the regulation of anxiety- and depression-like behaviors in an age-dependent manner.

  2. results indicate that spinophilin plays an important role in regulating the activity of Group I mGluRs as well as their influence on synaptic activity.

  3. COPS5 (zeige COPS5 Antikörper) overexpression reduced spinophilin in both the cortex (19%, p < 0.05) and the hippocampus (20%, p < 0.05), leading to significant deficits in learning and memory skills

  4. RanBP9 (zeige RANBP9 Antikörper) overexpression in transgenic mice led to striking reduction in the levels of spinophilin.

  5. Canonical betaAR-mediated signaling coupled to PKA activation results in phosphorylation of spinophilin, disrupting its interaction with alpha2AARs and accelerating alpha2AAR (zeige ADRA2A Antikörper) endocytic responses.

  6. Findings support the concept that the inhibitory effects of SPL (zeige SGPL1 Antikörper) on M3R (zeige CHRM3 Antikörper) activity are mediated by RGS4 (zeige RGS4 Antikörper).

  7. changes in spinophilin/CaMKII (zeige CAMK2G Antikörper) interactomes may contribute to changes in striatal dendritic spine density, morphology, and function during normal postnatal maturation and aging.

  8. these data suggest that spinophilin is an upstream regulator required for normal growth and excitation-contraction coupling, but is dispensable for beta-adrenergic stimulation of adult cardiomyocytes.

  9. Findings suggest that spinophilin restrains Angiotensin II-mediated sympathetic nervous system activation and is an unrecognized molecule with regard to central blood pressure control

  10. We suggest that Spn (zeige SPN Antikörper) may be the tumor suppressor gene located at 17q21.33 acting through Rb regulation.

Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) Antigen-Profil

Beschreibung des Gens

Spinophilin is a regulatory subunit of protein phosphatase-1 catalytic subunit (PP1\; see MIM 176875) and is highly enriched in dendritic spines, specialized protrusions from dendritic shafts that receive most of the excitatory input in the central nervous system (Allen et al., 1997

Alternative names and synonyms associated with Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B)

  • protein phosphatase 1, regulatory subunit 9B (Ppp1r9b) Antikörper
  • protein phosphatase 1, regulatory subunit 9B (PPP1R9B) Antikörper
  • Neb2 Antikörper
  • PPP1R6 Antikörper
  • PPP1R9 Antikörper
  • SPINO Antikörper
  • SPL Antikörper
  • Spn Antikörper

Bezeichner auf Proteinebene für PPP1R9B

PP1bp134 , neurabin 2 , neurabin-2 , neurabin-II , neural tissue-specific F-actin-binding protein II , nuerabin 2 , p130 , spinophilin , neurabin II , protein phosphatase 1, regulatory (inhibitor) subunit 9B , protein phosphatase 1, regulatory subunit 9B, spinophilin

GENE ID SPEZIES
84686 Rattus norvegicus
84687 Homo sapiens
217124 Mus musculus
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