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RAB11A, Member RAS Oncogene Family Proteine (RAB11A)

Bezeichnung:
RAB11A, Member RAS Oncogene Family Proteine (RAB11A)
Auf www.antikoerper-online.de finden Sie aktuell 16 RAB11A, Member RAS Oncogene Family (RAB11A) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RAB11A, Member RAS Oncogene Family Antikörper (114) und RAB11A, Member RAS Oncogene Family Kits (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 150 RAB11A, Member RAS Oncogene Family Produkte verfügbar.
Synonyme:
DDBDRAFT_0190819, DDBDRAFT_0191190, DDB_0190819, DDB_0191190, RAB11, rab11A, wu:fi15h09, YL8, zgc:103679
alle Proteine anzeigen Gen GeneID UniProt
RAB11A 8766 P62491
RAB11A 53869 P62492
RAB11A 81830 P62494

Weitere Synonyme anzeigen

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Am meisten referenzierte RAB11A, Member RAS Oncogene Family Proteine

  1. Human RAB11A Protein expressed in Escherichia coli (E. coli) - ABIN666996 : Gromov, Celis, Hansen, Tommerup, Gromova, Madsen: Human rab11a: transcription, chromosome mapping and effect on the expression levels of host GTP-binding proteins. in FEBS letters 1998 (PubMed)
    Zeige alle 2 Referenzen für ABIN666996

Weitere Proteine zu RAB11A, Member RAS Oncogene Family Interaktionspartnern

Xenopus laevis RAB11A, Member RAS Oncogene Family (RAB11A) Interaktionspartner

  1. During neural tube formation Rab11-positive recycling endosomes distribute to the medial apical cell junctions in the neural plate. Polarization was under the control of planar cell polarity signalling, and was necessary for neural plate folding.

  2. Rab11 and the associated motor protein Myosin V (zeige MYO5A Proteine) play essential roles in both endogenous and ectopic apical constriction, and might be involved in Vangl2 trafficking to the cell surface.

  3. Rab11 expression is required throughout the early embryo for proper left-right patterning.

  4. A requirement for Rab11 in multiciliated cells(MCC (zeige MCC Proteine)) development and support a two-step model, in which the initial polarization of MCC (zeige MCC Proteine) precursors is critical for their integration into the superficial cell layer.

Zebrafish RAB11A, Member RAS Oncogene Family (RAB11A) Interaktionspartner

  1. Pard3 (zeige PARD3 Proteine) and Rab11a are necessary for lumen formation in the neural rod.

  2. The established transgenic lines ubiquitously express EGFP fusions of Rab5c (zeige Rab5c Proteine) (early endosomes), Rab11a (recycling endosomes), and Rab7 (zeige RAB7A Proteine) (late endosomes) to study localization and dynamics during development.

Tomato (Solanum lycopersicum) RAB11A, Member RAS Oncogene Family (RAB11A) Interaktionspartner

  1. The results suggest that Rab11 regulates anterograde transport from the TGN to the plasma membrane and strongly implicate SYP122, rather than SYP121.

Human RAB11A, Member RAS Oncogene Family (RAB11A) Interaktionspartner

  1. Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation

  2. In colorectal carcinoma, overexpression of Rab11 was found to promote collective cell migration through the increased distribution of E-cadherin (zeige CDH1 Proteine), which enhanced cell-cell connections.

  3. A novel tribasic Golgi export signal directs cargo protein interaction with activated Rab11 and AP-1 (zeige FOSB Proteine)-dependent Golgi-plasma membrane trafficking.

  4. Analysis reveals novel aspects of the PI4KIIIb-Rab11 complex, specifically conformational changes induced in the switch regions of activated Rab11.

  5. Substituted V20 of Rab11A was found to interfere with proper localization of the water molecule, which mediated GTP (zeige AK3 Proteine) hydrolysis, resulting in GTP (zeige AK3 Proteine) being locked in an active form of Rab11A S20V.

  6. Data (including data from studies in knockout mice) suggest Munc13-4 binds to Rab11 and regulates trafficking of Rab11-containing vesicles; Munc13-4 appears to regulate final steps of Rab11-positive vesicle docking at plasma membrane in exocytosis.

  7. Rab11A and Rab11B (zeige RAB11B Proteine) differentially regulate intracellular trafficking of PAR1 (zeige MARK2 Proteine) through distinct endosomal sorting mechanisms

  8. Rab11a/Rab11 family-interacting protein 2 (zeige RAB11FIP2 Proteine)-mediated VE-cadherin (zeige CDH5 Proteine) recycling is required for formation of adherens junctions and restoration of vascular endothelial barrier integrity.

  9. Authors show that Rab11-GMPPNP-FIP3 (zeige IKBKG Proteine)-Rabin8 is more stable than Rab11-GMPPNP-Rabin8, owing to direct interaction between Rabin8 and FIP3 (zeige IKBKG Proteine) within the dual effector-bound complex.

  10. Mumps Virus release from the apical surface of polarized epithelial cells is facilitated by a Rab11-mediated transport system.

Mouse (Murine) RAB11A, Member RAS Oncogene Family (RAB11A) Interaktionspartner

  1. Rab11a/Rab11 family-interacting protein 2 (zeige RAB11FIP2 Proteine)-mediated VE-cadherin (zeige CDH5 Proteine) recycling is required for formation of adherens junctions and restoration of vascular endothelial barrier integrity.

  2. Rab11a-knockdown cells displayed mislocalization of STX3 (zeige STX3 Proteine) and the presentation of microvilli in the basolateral compartment

  3. Results define Glut3 to be a rab11-dependent trafficking cargo and suggest that impaired Glut3 trafficking arising from rab11 dysfunction underlies the glucose hypometabolism observed in Huntington's disease

  4. LMTK1 (zeige AATK Proteine) negatively controls dendritic formation by regulating Rab11A-positive endosomal trafficking.

  5. Rab11a critically controls mouse blastocyst development and soluble matrix metalloproteinase (zeige MMP20 Proteine) secretion

  6. Thus, Rab11a endosome controls intestinal host-microbial homeostasis at least partially via sorting Toll (zeige TLR4 Proteine)-like receptors, including Tlr9 (zeige TLR9 Proteine).

  7. The unusual morphology and sorting capacity of Rab11a compartments in primary proximal tubule cells may reflect a unique specialization of these cells to accommodate the functional demands of handling a high endocytic load.

  8. These results suggest that deficient activity of Rab11 is a novel mechanism for glucose hypometabolism in Huntington's disease.

  9. Enhanced axonal outgrowth is diminished by inactivation of Rab11A, placing LMTK1 (zeige AATK Proteine) upstream of Rab11A.

  10. A novel mechanism for Huntington's disease involves early deficits in the control of Rab11 activity arising from diminished Rab11 expression at recycling endosomes.

RAB11A, Member RAS Oncogene Family (RAB11A) Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with RAB11A, Member RAS Oncogene Family (RAB11A)

  • RAB11A, member RAS oncogene family (rab11a)
  • RAB11A, member RAS oncogene family (RAB11A)
  • RAB11a, member RAS oncogene family (rab11a)
  • Rab11 GTPase (Rab11a)
  • rab11A protein (rab11A)
  • Rab11a, GTPase (Rab11a)
  • Rab GTPase (rab11A)
  • rab11A, RAB family GTPase (rab11A)
  • RAB11a, member RAS oncogene family (Rab11a)
  • DDBDRAFT_0190819 Protein
  • DDBDRAFT_0191190 Protein
  • DDB_0190819 Protein
  • DDB_0191190 Protein
  • RAB11 Protein
  • rab11A Protein
  • wu:fi15h09 Protein
  • YL8 Protein
  • zgc:103679 Protein

Bezeichner auf Proteinebene für RAB11A

RAB11A, member RAS oncogene family , ras-related protein Rab-11A , Rab11 GTPase , rab11A protein , Rab11a, GTPase , rab11A, RAB family GTPase , RAB 11A, member oncogene family , rab-11 , 24KG , rab11 GTP-binding protein , tubulovesicle-associated protein

GENE ID SPEZIES
447589 Xenopus laevis
453523 Pan troglodytes
492487 Danio rerio
549235 Xenopus (Silurana) tropicalis
100174499 Pongo abelii
543749 Solanum lycopersicum
553904 Lotus japonicus
814090 Plasmodium falciparum 3D7
8617525 Dictyostelium discoideum AX4
10506107 Dictyostelium purpureum
8766 Homo sapiens
53869 Mus musculus
81830 Rattus norvegicus
403957 Canis lupus familiaris
534708 Bos taurus
415544 Gallus gallus
595117 Sus scrofa
100009072 Oryctolagus cuniculus
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