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Human Aryl Hydrocarbon Receptor ELISA Kit für Sandwich ELISA - ABIN414628
Kajta, Litwa, Rzemieniec, Wnuk, Lason, Zelek-Molik, Nalepa, Grzegorzewska-Hiczwa, Tokarski, Golas, Guzik, Grochowalski, Szychowski, Wojtowicz: Isomer-nonspecific action of dichlorodiphenyltrichloroethane on aryl hydrocarbon receptor and G-protein-coupled receptor 30 intracellular signaling in apoptotic neuronal cells. in Molecular and cellular endocrinology 2014
Identified structural features of AHR1beta associated with low TCDD sensitivity. Substitution of the entire ligand binding domain with the corresponding sequence from mouse AHR(b-1) dramatically increased TCDD responsiveness in transactivation assays.
Transient AHR activation and cytochrome P450 (zeige CYP ELISA Kits) 1A (CYP1A) induction in livers occurred during ANIT-induced hepatobiliary impairment in medaka.
These results establish that mo-DCs and mo-Macs are controlled by distinct transcription factors and show that AHR acts as a molecular switch for monocyte fate specification in response to micro-environmental factors.
Carbidopa is an AhR agonist and suppresses pancreatic cancer. Hence, Carbidopa could potentially be re-purposed to treat pancreatic cancer and possibly other cancers as well.
REVIEW: focus on the role of AhR in integrating signals from the diet and the intestinal flora to modulate ongoing inflammation in the central nervous system; also discussion of the potential therapeutic value of AhR agonists for multiple sclerosis and other autoimmune diseases
AhR controls COX-2 (zeige COX2 ELISA Kits) protein via mRNA stability.
Findings indicate integrin inhibition as a promising strategy to block both aryl hydrocarbon receptor (AhR) and transforming growth factor beta (TGF-beta)-controlled features of malignancy in glioblastoma.
Dependent on composition, mixtures of PAHs activate the AHR differently through varying transcription responses and expression of CYP1A1 (zeige CYP1A1 ELISA Kits)/COMT (zeige COMT ELISA Kits) target genes in granulosa non-tumor and granulosa tumor cell lines.
HRG (zeige NRG1 ELISA Kits)/HER2 (zeige ERBB2 ELISA Kits)/HER3 (zeige ERBB3 ELISA Kits) signaling promotes AhR-mediated Memo-1 (zeige MEMO1 ELISA Kits) expression and migration in colorectal cancer
To minimize oxidative stress, keratinocytes express nuclear factor-erythroid 2-related factor-2 (NRF2 (zeige NFE2L2 ELISA Kits)), a master switch for antioxidant signaling; fine-tuned crosstalk between aryl hydrocarbon receptor (AHR) and NRF2 (zeige GABPA ELISA Kits) mutually increases/decreases activation states; NRF2 (zeige GABPA ELISA Kits)-mediated dietary antioxidant phytochemicals up-/down-modulate AHR signaling leading to healthy skin, preventing dermatitis/skin cancer. [REVIEW]
Donor T cells lacking AhR demonstrate decreased acute graft versus host disease because of reduced donor T-cell proliferation early after transplant.
Cross-talk between pregnane X receptor (zeige NR1I2 ELISA Kits) and AhR plays a role in rifampicin regulation of CYP3A4 (zeige CYP3A4 ELISA Kits) gene expression.
steroid hormones, AhR and estrogen receptor beta (zeige ESR2 ELISA Kits) are affected by TCDD and genistein in granulosa cells of medium porcine follicles
AHR mRNA expression in follicular, theca, and granulosa cells suggest the involvement of AHR in the modulation of reproductive processes in the porcine ovary.
The results suggest AhR activation causes the loss of liver-specific and sexually dimorphic gene expression producing a functionally "de-differentiated" hepatic phenotype.
Study provides evidence supporting the importance of AHR in tumor progression and host survival through the upregulation of ISX (zeige ISX ELISA Kits) expression and promotion of tumor cell growth while restraining the expression of tumor suppressors in hepatocellular carcinoma (HCC (zeige FAM126A ELISA Kits)), and thereby suggests a plausible mechanistic link between AHR and HCC (zeige FAM126A ELISA Kits).
functional AhR expression is critical for skin barrier integrity and that AhR represents a molecular target for the development of therapeutic approaches for skin barrier diseases, including by dietary intervention.
Lipopolysaccharide (LPS (zeige TLR4 ELISA Kits)) stimulation increased the expression and activity of the immunoregulatory enzyme IDO1 (zeige IDO1 ELISA Kits) in hepatic stellate cells (HSCs), and LPS (zeige TLR4 ELISA Kits)/HSCs stimulated aryl hydrocarbon receptor (AhR) signaling in cocultured regulatory T cells.
this study shows that AhR-/- mice display impaired bone healing with delayed endochondral ossification
AhR(-/-) mice are not able to mount an Natural killer cell memory response to hapten rechallenge.
Hyperhomocysteinemia activates the AHR-CD36 (zeige CD36 ELISA Kits) pathway by increasing hepatic LXA4 content, which results in hepatic steatosis.
This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons.
aryl hydrocarbon receptor
, aryl hydrocarbon receptor 1
, aryl hydrocarbon receptor-like
, ah receptor
, aromatic hydrocarbon receptor
, class E basic helix-loop-helix protein 76
, Ah receptor
, dioxin receptor