anti-Human Spectrin beta Chain, Erythrocyte Antikörper für Enzyme Immunoassay

Recommended Spectrin beta Chain, Erythrocyte Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Spectrin beta Chain, Erythrocyte (SPTB) Antikörper
  • AI842465
  • D330027P03Rik
  • Gm1301
  • Spnb-1
  • Spnb1
  • ja
  • jaundiced
  • mKIAA4219
  • EL3
  • HS2
  • HSPTB1
  • SPH2
  • spectrin, beta, erythrocytic
  • spectrin beta, erythrocytic
  • SPTB
  • Sptb
Reaktivität
Human
30
2
2
1
Wirt
Maus
26
4
Klonalität
Monoklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
25
18
7
5
5
5
1
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Produktnummer ABIN110975
$ 401.50
Zzgl. Versandkosten $45.00

General

Antigen Spectrin beta Chain, Erythrocyte (SPTB) Antikörper
Reaktivität Human
(30), (2), (2), (1)
Wirt Maus
(26), (4)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Unkonjugiert
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
(25), (18), (7), (5), (5), (5), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität Recognizes alpha (240 kDa) and beta (220 kDa) subunits of Spectrin. This antibody has not been cross-adsorbed and may react with peptides from related species.
Cellular Localization: Cytoplasmic surface of the cell membrane.
Reinigung Ammonium Sulphate Fractionation
Immunogen Native Human beta Spectrin
Klon SPN-2-B12G3
Isotyp IgM

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Spectrin beta Chain (Erythrocyte) / SPTB (SPTB Antibody Abstract)
Hintergrund Spectrin is a major constituent of the erythrocyte skeleton accounting for 25 % of the total membrane protein and 75 % of the cytoskeletal mass. It is associated with the cytoplasmic surface of the membrane by attachment to ankyrin, a peripheral membrane protein. The membrane skeleton influences several cellular properties such as cell shape, restriction of mobility of the integral membrane protein exposed at the cell surface and transmembrane movement of phospholipids and cholesterol. On SDS PAGE gels erythrocyte spectrin appears as two bands referred to as alpha (240 kDa) and beta (220 kDa). While the simplest form of spectrin in solution is an alpha-beta heterodimer, spectrin can undergo self-association in various conditions to form a tetramer of alpha2-beta2. In recent years a large number of spectrin-like molecules have been found in non-erythroid cells. These proteins are known by such different names as fodrin, CBP I, calspectin and TW 260/240.Synonyms: Erythroid alpha-spectrin, SPTA
Gen-ID 6710
NCBI Accession NP_000338
UniProt P11277
Pathways Regulation of Actin Filament Polymerization

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer PBS, pH 7.2, containing 0.09 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C.