anti-Human erythrocyte Membrane Protein Band 4.9 (Dematin) Antikörper für Enzyme Immunoassay

Recommended erythrocyte Membrane Protein Band 4.9 (Dematin) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) Antikörper
  • MGC80597
  • MGC108072
  • EPB49
  • DMT
  • AI325486
  • Epb4.9
  • Epb49
  • dematin
  • erythrocyte membrane protein band 4.9 (dematin)
  • erythrocyte membrane protein band 4.9
  • dematin actin binding protein
  • epb49
  • EPB49
  • DMTN
  • LOC100357787
  • Dmtn
Epitop
AA 248-277, Middle Region
15
12
9
7
7
4
3
3
2
2
2
2
1
1
Reaktivität
Human
60
41
14
3
1
1
1
Wirt
Kaninchen
58
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
32
23
16
13
12
12
2
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN951882
$ 390.50
Zzgl. Versandkosten $45.00

General

Antigen erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) Antikörper
Epitop AA 248-277, Middle Region
(15), (12), (9), (7), (7), (4), (3), (3), (2), (2), (2), (2), (1), (1)
Reaktivität Human
(60), (41), (14), (3), (1), (1), (1)
Wirt Kaninchen
(58), (2)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(32), (23), (16), (13), (12), (12), (2), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Spezifität This antibody recognizes Human Dematin (Center).
Reinigung Affinity Chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 248-277 amino acids from the Central region of Human Dematin. Genename: EPB49
Isotyp Ig

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung Dematin (EPB49 Antibody Abstract)
Hintergrund Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]).Synonyms: DMT, EPB49, Erythrocyte membrane protein band 4.9
Molekulargewicht 45514 Da
Gen-ID 2039
NCBI Accession NP_001107607
Forschungsgebiet Signaling, Cytoskeleton, Microfilaments
Pathways Regulation of Actin Filament Polymerization

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Vugmeyster, Ostrovsky, Li: "Comparison of fast backbone dynamics at amide nitrogen and carbonyl sites in dematin headpiece C-terminal domain and its S74E mutant." in: Journal of biomolecular NMR, Vol. 47, Issue 2, pp. 155-62, 2010

Chen, Jiang, Khan, Chishti, McKnight: "Dematin exhibits a natively unfolded core domain and an independently folded headpiece domain." in: Protein science : a publication of the Protein Society, Vol. 18, Issue 3, pp. 629-36, 2009

Vugmeyster, McKnight: "Phosphorylation-induced changes in backbone dynamics of the dematin headpiece C-terminal domain." in: Journal of biomolecular NMR, Vol. 43, Issue 1, pp. 39-50, 2008

Vermeulen, Van Troys, Bourry, Dewitte, Rossenu, Goethals, Borremans, Vandekerckhove, Martins, Ampe: "Identification of the PXW sequence as a structural gatekeeper of the headpiece C-terminal subdomain fold." in: Journal of molecular biology, Vol. 359, Issue 5, pp. 1277-92, 2006

Frank, Vardar, Chishti, McKnight: "The NMR structure of dematin headpiece reveals a dynamic loop that is conformationally altered upon phosphorylation at a distal site." in: The Journal of biological chemistry, Vol. 279, Issue 9, pp. 7909-16, 2004

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (AA 248-277), (Middle Region) antibody (ABIN951882) Western blot analysis of Dematin  Antibody  in Y79 cell line lysates (35ug/lane).