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eotaxin promotes proliferation in vascular smooth muscle cells and triggers oxidative stress in a NADPH oxidase (zeige NOX1 ELISA Kits) dependent manner.
a receiver operating characteristic (ROC) curve analysis demonstrated CSF (zeige CSF2 ELISA Kits) CCL11 accurately distinguished CTE subjects from non-athlete controls and AD subjects
These studies characterized serum and intestinal wall eotaxin-1 levels in various inflammatory bowel disease patients and to explore the effect of targeting eotaxin-1 by specific antibodies in dextran sodium sulfate-induced colitis model.
this study shows that expression of CCL11 is increased in eosinophilic myocarditis patient (zeige CCR3 ELISA Kits)s compared to chronic lymphocytic myocarditis patients
Review: eotaxins (CCL11, CCL24 (zeige CCL24 ELISA Kits), and CCL26 (zeige CCL26 ELISA Kits)) play key role(s) during symptomatic inflammatory responses raised in response to allergic crisis of allergic asthma and atopic dermatitis
Eotaxin measured on the day of birth is useful for identifying extremely low birth weight infants at risk of bronchopulmonary dysplasia/death.
The results of this study suggested that eotaxin-1 as a novel modifier of Alzheimer's disease age at onset and open potential avenues for therapy.
ANDV caused long-term elevated levels of eotaxin-1, IL-6 (zeige IL6 ELISA Kits), IL-8 (zeige IL8 ELISA Kits), IP-10 (zeige CXCL10 ELISA Kits), and VEGF-A (zeige VEGFA ELISA Kits) that peaked 20-25 days after infection
The A allele in eotaxin 67 G/A polymorphism is associated with worse survival in CAD (zeige CAD ELISA Kits) patients.
co-cultures of KYSE-410 cells and cancer-associated fibroblasts (CAF (zeige KAT2B ELISA Kits)) were investigated. Similar to SF, Has2 (zeige HAS2 ELISA Kits) and Ccl5 (zeige CCL5 ELISA Kits) were up-regulated and Ccl11 was down-regulated in CAF (zeige KAT2B ELISA Kits) in co-culture.
CCL11 promotes migration and proliferation of mouse neural progenitor cells.
this study shows that eosinophil trafficking to the heart is dependent on the eotaxin-CCR3 (zeige CCR3 ELISA Kits) pathway in a mouse model of experimental autoimmune myocarditis
Blocking antibodies against RANTES (zeige CCL5 ELISA Kits) and eotaxin reduced the infiltration of CD4 (zeige CD4 ELISA Kits)(+) and CD8 (zeige CD8A ELISA Kits)(+) T cells into the nigra, attenuated nigral expression of proinflammatory molecules, and suppressed nigral activation of glial cells. These findings paralleled dopaminergic neuronal protection, normalized striatal neurotransmitters, and improved motor functions in MPTP (zeige PTPN2 ELISA Kits)-intoxicated mice.
These results indicate that CCL11 was responsible for the limited angiogenesis and necrosis by inducing and attracting eosinophils in the tumors.
Study demonstrated that CCL11 is primarily produced by activated astrocytes in the CNS, activates microglia to produce ROS (zeige ROS1 ELISA Kits) via NOX1 (zeige NOX1 ELISA Kits), and exacerbates excitotoxic neuronal death
PAR2 (zeige F2RL1 ELISA Kits) activation through endogenous mast cell tryptase activity could be required, at least partially, to mediate CCL11-induced eosinophil migration
The chemokines monocyte chemotactic protein 1 (MCP1 (zeige CCL2 ELISA Kits)), MIP1alpha, MIP1beta (zeige CCL4 ELISA Kits), interferon gamma (zeige IFNG ELISA Kits)-induced protein 10 (IP-10 (zeige CXCL10 ELISA Kits)), and eotaxin were induced in Saa1 (zeige SAA1 ELISA Kits) TG mice.
Aged mice had similar levels of IL-1beta (zeige IL1B ELISA Kits), TNF (zeige TNF ELISA Kits), IFN-gamma (zeige IFNG ELISA Kits), IL-17 (zeige IL17A ELISA Kits), and granulocyte colony-stimulating factor (zeige CSF3 ELISA Kits) following S. pneumoniae infection, compared with young mice, but increased levels of the chemokines CXCL9 (zeige CXCL9 ELISA Kits), CXCL12 (zeige CXCL12 ELISA Kits), CCL3 (zeige CCL3 ELISA Kits), CCL4 (zeige CCL4 ELISA Kits), CCL5 (zeige CCL5 ELISA Kits), CCL11, and CCL17 (zeige CCL17 ELISA Kits).
Protection of montelukast on OVA-induced eosinophilic gastroenteritis via modulating IL-5 (zeige IL5 ELISA Kits), eotaxin-1 and MBP (zeige MBP ELISA Kits) expression.
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
eosinophil chemotactic protein
, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
, C-C motif chemokine 11
, small chemokine (C-C motif) ligand 11
, small inducible cytokine A11
, small-inducible cytokine A11
, small inducible cytokine subfamily A11
, chemokine CCL11/EOTAXIN