anti-Maus CAND1 Antikörper für Enzyme Immunoassay

Recommended CAND1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cullin-Associated and Neddylation-Dissociated 1 (CAND1) Antikörper
  • cand2
  • tip120
  • tip120a
  • 2310038O07Rik
  • 6330512O03Rik
  • AI195005
  • AI846556
  • D10Ertd516e
  • Tp120a
  • mKIAA0829
  • TIP120
  • TIP120A
  • Tip120
  • Tip120A
  • fb78a05
  • wu:fb78a05
  • zgc:55729
  • ATCAND1
  • CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1
  • ETA2
  • HEMIVENATA
  • HVE
  • T8K22.14
  • T8K22_14
  • cullin-associated and neddylation dissociated
  • cullin-associated and neddylation-dissociated 1
  • cullin associated and neddylation disassociated 1
  • cullin-associated NEDD8-dissociated protein 1
  • CAND1
  • cand1
  • Cand1
Epitop
C-Term, AA 1130-1143
11
6
6
5
5
2
2
2
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
45
15
12
7
6
6
5
5
5
3
3
3
2
2
2
Wirt
Kaninchen
32
13
Klonalität
Polyklonal
Applikation
Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
42
20
15
15
13
10
4
2
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN117945
$ 419.10
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN117944 EIA IP WB Rabbit N-Term, AA 11-24 Anmelden zum Anzeigen Polyclonal 9
1 ABIN303072 EIA IHC (p) IP WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Cullin-Associated and Neddylation-Dissociated 1 (CAND1) Antikörper
Epitop C-Term, AA 1130-1143
(11), (6), (6), (5), (5), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(45), (15), (12), (7), (6), (6), (5), (5), (5), (3), (3), (3), (2), (2), (2)
Wirt Kaninchen
(32), (13)
Klonalität
Polyklonal
Applikation Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
(42), (20), (15), (15), (13), (10), (4), (2), (1)
Pubmed 9 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CAND1 Antikörper

Target Details CAND1 Anwendungsinformationen Handhabung Referenzen für anti-CAND1 Antikörper (ABIN117945) Bilder
Sequenz Human CAND2 (TIP120B) (1143 aa 125.4 kDa): 1 mstaafhiss llekmtssdk dfrfmatsdl mselqkdsiq ldedserkvv kmllrlledk 61 ngevqnlavk wlgvplgafh asllhcllpq lssprlavrk ravgalghla aacstdlfve 121 ladhlldrlp gprvptspta irtliqclgs vgrqaghrlg ahldrlvplv edfcnlddde 181 lresclqafe aflrkcpkem gphvpnvtsl clqyikhdpn ynydsdedee qmetedsefs 241 eqesedeysd dddmswkvrr aaakciaali ssrpdllpdf hctlapvlir rfkereenvk --- 901 vkflisdqph pidpllksfi gefmeslqdp dlnvrratla ffnsavhnkp slvrdllddi 961 lpllyqetki rrdlirevem gpfkhtvddg ldvrkaafec mysllesclg qldiceflnh 1021 vedglkdhyd irmltfimva rlatlcpapv lqrvdrliep lratctakvk agsvkqefek 1081 qdelkrsamr avaalltipe vgkspimadf ssqirsnpel aalfesiqkd sasapstdsm 1141 els
Spezifität This antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. It reacts with human, rat and mouse CAND2/TIP120B. Cross reactivity does occur with human, rat and mouse CAND1/TIP120A. Cross reactivity with CAND2 from other sources is not known.
Reinigung Delipidation and defibrination.
Immunogen This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1130-1143 of Human CAND2/TIP120B (C-terminal) coupled to KLH.

Target Details CAND1

Produktdetails anti-CAND1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CAND1 Antikörper (ABIN117945) Bilder zurück nach oben
Antigen
Andere Bezeichnung CAND1 (CAND1 Antibody Abstract)
Hintergrund CAND2 is also known as TIP120B, and TATA-binding protein-interacting protein 120B. While both CAND1 (TIP120A) and CAND2 (TIP120B) are TATA-binding proteins and form complexes with various nuclear proteins involved in the control of eukaryotic gene transcription, CAND2 (TIP120B) is expressed specifically in muscle and heart tissue. This is contrary to the ubiquitous expression of CAND1 (TIP120A). TIP120 homologs exist in various higher eukaryotes including D. melanogaster, C. elegans, and A. thaliana. TIP120B is 60 % identical in amino acid sequence to TIP120A.Synonyms: Cullin-associated NEDD8-dissociated protein 1, Cullin-associated and neddylation-dissociated protein 1, KIAA0829, TBP-interacting protein TIP120A, TBP-interacting protein of 120 kDa A, TIP120, TIP120A, p120 CAND1
Gen-ID 55832
NCBI Accession NP_060918
UniProt Q86VP6
Forschungsgebiet Apoptosis/Necrosis, Proteasome
Pathways Regulation of Actin Filament Polymerization

Anwendungsinformationen

Produktdetails anti-CAND1 Antikörper Target Details CAND1 Handhabung Referenzen für anti-CAND1 Antikörper (ABIN117945) Bilder zurück nach oben
Applikationshinweise Western blot (1: 500-1: 1,000). Immunoprecipitation: The antibody immunoprecipitates in vitro translated protein andprotein from transfected cell lysates (using HeLa and NIH-3T3, and others). Coimmunoprecipitation of related proteins has not been tested. A 125.4 kDa bandcorresponding to human CAND2 is detected. CAND2 is specifically expressed in muscle
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CAND1 Antikörper Target Details CAND1 Anwendungsinformationen Referenzen für anti-CAND1 Antikörper (ABIN117945) Bilder zurück nach oben
Format Liquid
Konzentration 85 mg/mL (by Refractometry)
Handhabung Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-CAND1 Antikörper (ABIN117945)

Produktdetails anti-CAND1 Antikörper Target Details CAND1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Concejero, Chen, Wang, Wang, Lin, Liu, Yang, Yong, Lin, Jawan, Huang, Cheng, Eng: "Living donor liver transplantation for hepatocellular carcinoma: a single-center experience in Taiwan." in: Transplantation, Vol. 85, Issue 3, pp. 398-406, 2008

Allgemeine Veröffentlichungen

Feng, Shen, Sullivan, Rubio, Xiong, Sun, Deng: "Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation." in: The Plant cell, Vol. 16, Issue 7, pp. 1870-82, 2004

Cheng, Dai, Zhao: "AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis." in: Plant physiology, Vol. 135, Issue 2, pp. 1020-6, 2004

Oshikawa, Matsumoto, Yada, Kamura, Hatakeyama, Nakayama: "Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1." in: Biochemical and biophysical research communications, Vol. 303, Issue 4, pp. 1209-16, 2003

Liu, Furukawa, Matsumoto, Xiong: "NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases." in: Molecular cell, Vol. 10, Issue 6, pp. 1511-8, 2002

Zheng, Yang, Harrell, Ryzhikov, Shim, Lykke-Andersen, Wei, Sun, Kobayashi, Zhang: "CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex." in: Molecular cell, Vol. 10, Issue 6, pp. 1519-26, 2002

Makino, Yogosawa, Kayukawa, Coin, Egly, Wang, Roeder, Yamamoto, Muramatsu, Tamura: "TATA-Binding protein-interacting protein 120, TIP120, stimulates three classes of eukaryotic transcription via a unique mechanism." in: Molecular and cellular biology, Vol. 19, Issue 12, pp. 7951-60, 2000

Jentsch, Pyrowolakis: "Ubiquitin and its kin: how close are the family ties?" in: Trends in cell biology, Vol. 10, Issue 8, pp. 335-42, 2000

Makino, Yoshida, Yogosawa, Tanaka, Muramatsu, Tamura: "Multiple mammalian proteasomal ATPases, but not proteasome itself, are associated with TATA-binding protein and a novel transcriptional activator, TIP120." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 4, Issue 9, pp. 529-39, 1999

Bilder

Produktdetails anti-CAND1 Antikörper Target Details CAND1 Anwendungsinformationen Handhabung Referenzen für anti-CAND1 Antikörper (ABIN117945) zurück nach oben
Bilder des Herstellers
 image for anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1130-1143), (C-Term) antibody (ABIN117945) Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifier...