Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Proteine (SLC9A3R1)

Bezeichnung:
Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Proteine (SLC9A3R1)
Auf www.antikoerper-online.de finden Sie aktuell 9 Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Antikörper (111) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 125 Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Produkte verfügbar.
Synonyme:
EBP-50, EBP50, NHE-RF, NHERF, NHERF-1, NHERF1, NPHLOP2, SLC9A3R1
alle Proteine anzeigen Gen GeneID UniProt
SLC9A3R1 9368 O14745
SLC9A3R1 26941 P70441
SLC9A3R1 59114 Q9JJ19

Weitere Synonyme anzeigen

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Am meisten referenzierte Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Proteine

  1. Human SLC9A3R1 Protein expressed in HEK-293 Cells - ABIN2732190 : Wang, Qin, Zhu: Expression of Na+/H+ exchanger regulatory factor 1 in autosomal-dominant polycystic kidney disease. in The Journal of international medical research 2015 (PubMed)

Weitere Proteine zu Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Interaktionspartnern

Mouse (Murine) Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) Interaktionspartner

  1. The results provide evidence that NHERF1 (zeige SLC9A3R2 Proteine) mediates K(+) current activity through acceleration of the surface expression of ROMK1 (zeige KCNJ1 Proteine) K(+) channels in M-1 cells.

  2. The NHERF1 (zeige SLC9A3R2 Proteine) is as putative molecular organizer of signal transduction in vomeronasal neurons.

  3. we show here that NHERF1 (zeige SLC9A3R2 Proteine) loss from the PM is oncogenic in vivo through its influence on Wnt (zeige WNT2 Proteine)-APC (zeige APC Proteine)-beta-catenin (zeige CTNNB1 Proteine) and Hippo-YAP (zeige YAP1 Proteine) pathways.

  4. NHERF1 (zeige SLC9A3R2 Proteine) mediates ANG II (zeige AGT Proteine)-induced activation of renal NHE3 (zeige SLC9A3 Proteine), which requires coordination between IRBIT (zeige AHCYL1 Proteine) and the NHERF1 (zeige SLC9A3R2 Proteine) PDZ1 domain in binding and transporting NHE3 (zeige SLC9A3 Proteine)

  5. These results indicate that PTH (zeige PTH Proteine)-mediated inhibition of renal phosphate transport involves phosphorylation of S77 of the NHERF-1 PDZ I domain and the dissociation of NHERF-1/Npt2a (zeige SLC34A1 Proteine) complexes.

  6. Results strongly support an important role for NHERF1 (zeige SLC9A3R2 Proteine) in the regulation of Planar Cell Polarity signaling and the development of functional motile cilia.

  7. the activation of PTEN and NHERF-1 may impede the evolution of macrophages beyond the M1 into M2 phenotype in tumor microenvironment.

  8. Data show that interaction of the inducible nitric oxide synthase (iNOS (zeige NOS2 Proteine)) C-terminus with the PDZ domains of EBP50 protein or Pdzk1 (zeige PDZK1 Proteine) protein CAP70 (zeige PDZK1 Proteine) resulted greater nitric oxide (NO) synthesis.

  9. The expression of EBP50 was not significantly different in the pseudopregnant uterus and decreased in the uteri subjected to activation of delayed implantation.

  10. NHERF1 (zeige SLC9A3R2 Proteine) is differentially distributed to rafts and non-raft brush border membrane fractions of NHE3 (zeige SLC9A3 Proteine).

Cow (Bovine) Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) Interaktionspartner

  1. study found mainly nuclear localization of EBP50 in interphase cells, and its redistribution to cytoplasm during mitosis parallel with its phosphorylation; PP2A (zeige PPP2R2B Proteine) was identified as an interacting protein of EBP50 during pro-, prometa-, meta-, ana (zeige BTG3 Proteine)-, telophase, and early cytokinesis

Human Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) Interaktionspartner

  1. Data demonstrated that EBP50 overexpression inhibited the adhesion and migration of breast and cervical cancer cell lines and suppressed MMP-2 (zeige MMP2 Proteine) activity in these cells; while its knockdown promoted cell adhesion and migration, and enhanced the activity of MMP-2 (zeige MMP2 Proteine).This study reveals the anti-metastatic effect and a new mechanism of EBP50 action in breast and cervical cancer cells.

  2. Data provide evidence for an important role of NHERF1 in the epithelial-mesenchymal transition of non-small-cell lung cancer cells, as well as migration.

  3. This interaction is promoted by EPAC1 (zeige RAPGEF3 Proteine) activation, triggering its translocation to the plasma membrane and binding to NHERF1. Our findings identify a new CFTR (zeige CFTR Proteine)-interacting protein and demonstrate that cAMP activates CFTR (zeige CFTR Proteine) through two different but complementary pathways - the well-known PKA-dependent channel gating pathway and a new mechanism regulating endocytosis that involves EPAC1 (zeige RAPGEF3 Proteine).

  4. we show here that NHERF1 loss from the PM is oncogenic in vivo through its influence on Wnt (zeige WNT2 Proteine)-APC (zeige APC Proteine)-beta-catenin (zeige CTNNB1 Proteine) and Hippo-YAP (zeige YAP1 Proteine) pathways.

  5. High EBP50 expression is associated with cervical cancer.

  6. Using neutron spin echo spectroscopy (NSE (zeige ENO2 Proteine)), the authors show salt-concentration-dependent excitation of nanoscale motion at the tip of the C-terminal tail in the phosphomimic S339D/S340D mutant.

  7. data highlight sequences in PTHR that contribute to NHERF1 interaction and can be altered to prevent phosphorylation-mediated inhibition

  8. NHERF1 acts with PMCA2 (zeige ATP2B2 Proteine) to regulate HER2 (zeige ERBB2 Proteine) signaling and membrane retention in breast cancers

  9. COOH-terminal sequences mediate enhanced NHERF1 interaction and facilitate the localization of CFTR (zeige CFTR Proteine).

  10. Na/H exchanger regulatory factor 1 (NHERF1) expression Is downregulated in cisplatin-resistant HeLa cells.

Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) Protein Überblick

Protein Überblick

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

Alternative names and synonyms associated with Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1)

  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (SLC9A3R1)
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (SLC9A3R1)
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (Slc9a3r1)
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (Slc9a3r1)
  • EBP-50 Protein
  • EBP50 Protein
  • NHE-RF Protein
  • NHERF Protein
  • NHERF-1 Protein
  • NHERF1 Protein
  • NPHLOP2 Protein
  • SLC9A3R1 Protein

Bezeichner auf Proteinebene für SLC9A3R1

Na(+)/H(+) exchange regulatory cofactor NHE-RF1 , Na+/H+ exchange regulatory co-factor , ezrin-radixin-moesin binding phosphoprotein-50 , ezrin-radixin-moesin-binding phosphoprotein 50 , regulatory cofactor of Na(+)/H(+) exchanger , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1 , solute carrier family 9 isoform A3 regulatory factor 1 , EBP50 , NHERF-1 , sodium-hydrogen exchanger regulatory factor 1 , solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 , solute carrier family 9 sodium/hydrogen exchanger member 3 regulator 1 , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1 , ERM-binding phosphoprotein , Na(+)/H(+) exchange regulatory cofactor NHE-RF , solute carrier family 9 isoform 3 regulatory factor 1

GENE ID SPEZIES
9368 Homo sapiens
422108 Gallus gallus
454865 Pan troglodytes
483299 Canis lupus familiaris
703933 Macaca mulatta
780527 Ovis aries
100009196 Oryctolagus cuniculus
100233201 Sus scrofa
26941 Mus musculus
59114 Rattus norvegicus
505242 Bos taurus
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