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IL16 Protein

IL16 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935480
  • Target Alle IL16 Proteine anzeigen
    IL16 (Interleukin 16 (IL16))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 15
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Quelle
    • 25
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    SAASASAASD VSVESTAEAT VCTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETVQPG DEILQLGGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QSKETTAAGD S
    Produktmerkmale
    Purified recombinant Human IL16 protein
    Expression System: E.coli
    Bioactivity: Determined by its ability ot chemoattract human CD4+ T-lymphoytes using a concentration range of 50.0-100.0 ng/mL.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL16 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Liu, Mills, Dixon, Vennarini, Cunningham, Del Vecchio, Das, Glass: "IL-16 signaling specifically induces STAT6 activation through CD4." in: Cytokine, Vol. 38, Issue 3, pp. 145-50, (2007) (PubMed).

  • Target
    IL16 (Interleukin 16 (IL16))
    Andere Bezeichnung
    IL16 (IL16 Produkte)
    Synonyme
    IL16 Protein, LCF Protein, NIL16 Protein, PRIL16 Protein, prIL-16 Protein, mKIAA4048 Protein, IL-16 Protein, interleukin 16 Protein, IL16 Protein, Il16 Protein
    Hintergrund
    IL16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL16 exists predominantly as a noncovalently linked multimer, but that some IL16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL16 also induces expression of IL2 receptor (IL2R) and MHC class II molecules on CD4 + T cells. Human and Mouse IL16 show significant cross-species reactivity.
    Alternative Names: IL-16 protein, IL16, IL 16 protein, IL-16 protein, IL-16, Lymphocyte Chemoattractant Factor protein, Interleukin 16 protein, IL 16, LCF protein
    Molekulargewicht
    13.5 kDa
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