Interleukin 6 (IL6) (Active) Protein

Details zu Produkt Nr. ABIN780926, Anbieter: Anmelden zum Anzeigen
Proteinname
  • Il-6
  • ILg6
  • Ifnb2
  • BSF2
  • HGF
  • HSF
  • IFNB2
  • IL-6
  • CHIL-6
  • il6
  • interleukin 6
  • interleukin 6 (interferon, beta 2)
  • interleukin-6
  • Il6
  • IL6
  • LOC517016
  • il-6
Spezies
Maus
85
44
30
5
5
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Quelle
Escherichia coli (E. coli)
136
26
14
7
3
2
2
1
1
Protein-Typ
Recombinant
Biologische Aktivität
Active
Applikation
In vitro Assay (in vitro), In vivo Studies (in vivo), ELISA, Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Sequenz MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
Spezifität Recombinant mouse IL-6 is a non-glycosylated protein, containing 187 amino acids, with a molecular weight of 21.7 kDa.
Kreuzreaktivität Human, Ratte (Rattus)
Reinheit ≥ 95%
Sterilität Sterile filtered
Endotoxin-Niveau ≤ 1.00 LAL (EUs/ug)
Biological Activity Comment
  • Bioactivity Assay: 7TD1 cell proliferation
  • Bioactivity Acceptance Criteria ED50 (ng/ml): 1 ng/mL
  • Bioactivity Acceptance Criteria (Units/mg): 1 x 10^6 units/mg
Hintergrund Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune response upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions, is capable of promoting fever, and signals through the cell-surface type I cytokine receptor complex containing the IL-6Ra and gp130 chains. Human IL-6 is active on mouse and rat cells.

Alternate Names: IFN-β2, B-cell Differentiation Factor, BSF-2, HSF, MGI-2
Molekulargewicht Monomer: 21.9 MW Monomer/Total (kDa)
UniProt P08505
Pathways Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis
Applikationshinweise Optimal working dilution should be determined by the investigator.
Kommentare

Media Components: Luria Broth

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Sterile 10 mM HCI at 0.1 mg/mL
Buffer Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing : 0.1 % Trifluoroacetic Acid (TFA)
Konservierungsmittel Without preservative
Handhabung Centrifuge vial before opening.
Lagerung 4 °C/-20 °C/-80 °C
Informationen zur Lagerung 12 months from date of receipt when stored at -20°C to-80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.
Haltbarkeit 12 months
Bilder des Herstellers
 image for Interleukin 6 (IL6) (Active) protein (ABIN780926) Interleukin 6 (IL6) (Active) protein
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