BID Protein (AA 1-195)

Produktnummer ABIN668038

Produktdetails

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-195

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Produktmerkmale: BID, 1-195aa, Human, Recombinant, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20 mM Tris-HCl pH 8.0, 20% glycerol.

Lagerung: 4 °C

Antigendetails

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Andere Bezeichnung: BID (BID Produkte)

Synonyme: FP497 Protein, 2700049M22Rik Protein, AI875481 Protein, AU022477 Protein, BID Protein, bid Protein, si:ch211-238n5.6 Protein, fp497 Protein, xbid Protein, DKFZp469E066 Protein, BH3 interacting domain death agonist Protein, BH3 interacting domain death agonist S homeolog Protein, BID Protein, Bid Protein, bida Protein, bid.S Protein, bid Protein

Hintergrund: BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases. Recombinant BID protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: FP497, MGC15319, MGC42355, BH3 interacting domain death agonist isoform 2, BID, BH3 interacting domain death agonist isoform 2 Apoptotic death agonist, Apoptotic death agonist BID, BH3 interacting domain death agonist, HGNC:1050, BH3 interacting domain death agonist p11, BH3 interacting domain death agonist p13, BH3 interacting domain death agonist p15, BID isoform ES(1b), BID isoform L(2), Desmocollin type 4, Human BID coding sequence, OTTHUMP00000196197, p11 BID, p13 BID, p15 BID, p22 BID. NCBI no.: NP_001187

Molekulargewicht: 21.9 kDa (195 aa), confirmed by MALDI-TOF.

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity