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Grancalcin Protein (AA 1-217) (His tag)

GCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN7279305
  • Target Alle Grancalcin (GCA) Proteine anzeigen
    Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-217
    Spezies
    • 9
    • 2
    Human
    Quelle
    • 8
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses Grancalcin Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    GCA, 1-217aa, Human, His tag, E.coli
    Reinheit
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product GCA Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/ml (determined by BCA assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl
    Lagerung
    4 °C
  • Target
    Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
    Andere Bezeichnung
    GCA (GCA Produkte)
    Synonyme
    Grancalcin Protein, 5133401E04Rik Protein, AI573844 Protein, GCL Protein, zgc:92027 Protein, grancalcin Protein, Grancalcin Protein, zgc:92027 Protein, GCA Protein, gran Protein, LOC100280890 Protein, Gca Protein
    Hintergrund
    GCA, also known as Grancalcin, is calcium-binding protein that is especially abundant in human neutrophils. It belongs to the penta EF-hand (PEF) subfamily of EF-hand proteins, which also comprises calpain, sorcin, peflin, and ALG-2. This protein undergoes important conformational changes upon binding of calcium, which subsequently exposes hydrophobic amino acid residues, which direct the protein to hydrophobic surfaces. It interacts with L-plastin, a protein known to have actin bundling activity, which suggests that GCA may play a role in the regulation of neutrophils adhesion. Recombinant human GCA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Grancalcin, GCL. NCBI no.: NP_036330
    Molekulargewicht
    26.1 kDa (237aa), confirmed by MALDI-TOF
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