Grancalcin Protein (AA 1-217) (His tag)
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- Target Alle Grancalcin (GCA) Proteine anzeigen
- Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-217
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Grancalcin Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Produktmerkmale
- GCA, 1-217aa, Human, His tag, E.coli
- Reinheit
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product GCA Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/ml (determined by BCA assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl
- Lagerung
- 4 °C
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- Target
- Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
- Andere Bezeichnung
- GCA (GCA Produkte)
- Synonyme
- Grancalcin Protein, 5133401E04Rik Protein, AI573844 Protein, GCL Protein, zgc:92027 Protein, grancalcin Protein, Grancalcin Protein, zgc:92027 Protein, GCA Protein, gran Protein, LOC100280890 Protein, Gca Protein
- Hintergrund
- GCA, also known as Grancalcin, is calcium-binding protein that is especially abundant in human neutrophils. It belongs to the penta EF-hand (PEF) subfamily of EF-hand proteins, which also comprises calpain, sorcin, peflin, and ALG-2. This protein undergoes important conformational changes upon binding of calcium, which subsequently exposes hydrophobic amino acid residues, which direct the protein to hydrophobic surfaces. It interacts with L-plastin, a protein known to have actin bundling activity, which suggests that GCA may play a role in the regulation of neutrophils adhesion. Recombinant human GCA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Grancalcin, GCL. NCBI no.: NP_036330
- Molekulargewicht
- 26.1 kDa (237aa), confirmed by MALDI-TOF
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