RAP1A Protein (AA 1-181) (His tag)

Produktnummer ABIN667792

Produktdetails

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-181

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RAP1A Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: RAP1A, 1-181aa, Human, His tag, E.coli

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 5mM DTT, 200mM NaCl

Lagerung: 4 °C

Antigendetails

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Andere Bezeichnung: RAP1A (RAP1A Produkte)

Synonyme: KREV-1 Protein, KREV1 Protein, RAP1 Protein, SMGP21 Protein, AI848598 Protein, G-22K Protein, Krev-1 Protein, Rap1 Protein, RAP-1A Protein, rap 1A Protein, wu:fc66g06 Protein, zgc:86676 Protein, krev-1 Protein, krev1 Protein, rap1 Protein, RAP1A, member of RAS oncogene family Protein, RAS-related protein 1a Protein, RAP1A, member of RAS oncogene family a Protein, RAP1A, member of RAS oncogene family L homeolog Protein, RAP1A Protein, Rap1a Protein, rap1aa Protein, rap1a.L Protein

Hintergrund: Ras-related protein Rap-1A (RAP1A) belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. This Protein Induces morphological reversion of a cell line transformed by a Ras oncogene and Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Recombinant human RAP1A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: KREV1, G-22K, C21KG, Ras-related protein Rap-1A, G 22K, GTP binding protein smg p21A, KREV 1, OTTHUMP00000013741, RAP 1A, RAP1, RAP1A member of RAS oncogene family , Ras related protein Krev 1, Ras related protein Rap 1A, RAS related protein RAP1A, SMGP21. NCBI no.: NP_001010935

Molekulargewicht: 22.8kDa (201aa) confirmed by MALDI-TOF

Pathways: T-Zell Rezeptor Signalweg, Neurotrophin Signalübertragung, Signaling of Hepatocyte Growth Factor Receptor