Chromogranin A Protein (CHGA) (AA 19-457) (His tag)

Produktnummer ABIN667739

Dieses Recombinant Chromogranin A-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Chromogranin A Protein (CHGA) (AA 19-457) (His tag) (ABIN667739)

Target: Chromogranin A (CHGA)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 80 %

Produktdetails

Proteineigenschaft: AA 19-457

Aufreinigungstag / Konjugat: Dieses Chromogranin A Protein ist gelabelt mit His tag.

Sequenz: LPVNSPMNK GDTEVMKCIV EVISDTLSKP SPMPVSQECF ETLRGDERIL SILRHQNLLK ELQDLALQGA KERAHQQKKH SGFEDELSEV LENQSSQAEL KEAVEEPSSK DVMEKREDSK EAEKSGEATD GARPQALPEP MQESKAEGNN QAPGEEEEEE EEATNTHPPA SLPSQKYPGP QAEGDSEGLS QGLVDREKGL SAEPGWQAKR EEEEEEEEEA EAGEEAVPEE EGPTVVLNPH PSLGYKEIRK GESRSEALAV DGAGKPGAEE AQDPEGKGEQ EHSQQKEEEE EMAVVPQGLF RGGKSGELEQ EEERLSKEWE DSKRWSKMDQ LAKELTAEKR LEGQEEEEDN RDSSMKLSFR ARAYGFRGPG PQLRRGWRPS SREDSLEAGL PLQVRGYPEE KKEEEGSANR RPEDQELESL SAIEAELEKV AHQLQALRRG

Produktmerkmale: Chromogranin-A , 19-457aa, Human, His-tagged, Recombinant, E.coli

Aufreinigung: > 80% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 7.5) containing 2 mM EDTA, 0.1 mM PMSF, 10 % glycerol

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Chromogranin A (CHGA)

Andere Bezeichnung: Chromogranin A/CHGA

Hintergrund: Chromogranin A is a member of the chromogranin/secretogranin (granins) family of neuroendocrine secretory proteins. Chromogranin A (CgA) represents the major soluble protein co-stored and co-released with catecholamines, within chromaffin cells secretory granules. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. It is considered a diagnostic and prognostic marker of several diseases, including a variety of tumours and cardiac heart failure. Recombinant human Chromogranin A, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Molekulargewicht: 51.2 kDa (460aa) (Molecular weight on SDS-PAGE will appear higher)

NCBI Accession: NP_001266

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling