RAB23 Protein (AA 1-234) (His tag)

Produktnummer ABIN667606

Produktdetails

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-234

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RAB23 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: RAB23, 1-234aa, Human, His tag E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 1mM DTT, 0.1mM PMSF

Lagerung: 4 °C

Antigendetails

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Andere Bezeichnung: RAB23 (RAB23 Produkte)

Synonyme: MGC82152 Protein, hspc137 Protein, zgc:110261 Protein, AW545388 Protein, opb Protein, opb2 Protein, HSPC137 Protein, Rab23-like Protein, RAB23, member RAS oncogene family S homeolog Protein, RAB23, member RAS oncogene family Protein, ras-related protein Rab-23 Protein, rab23.S Protein, RAB23 Protein, rab23 Protein, Rab23 Protein

Hintergrund: RAB23, also known as ras-related protein Rab23, is a member of the Rab family of proteins and localizes to the cytoplasmic side of the cell membrane. This protein is thought to to play a role in intracellular protein transportation and signal transduction mediated by small GTPases. RAB23 is an essential negative regulator of the Sonic hedgehog signaling pathway. Mutations in the gene encoding RAB23 may result in Carpenter syndrome a condition characterized by obesity, cardiac defects, polysyndactyly and craniosynostosis. Recombinant human RAB23 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Ras-related protein Rab-23, DKFZp781H0695, HSPC137, MGC8900. NCBI no.: NP_057361

Molekulargewicht: 28.5 kDa (254aa), confirmed by MALDI-TOF

Pathways: Tube Formation